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Berberine

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Identification
Molecular formula
C20H18NO4
CAS number
2086-83-1
IUPAC name
2,3-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium
State
State

At room temperature, berberine is found in a solid state, specifically as a crystalline powder.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
336.36g/mol
Molar mass
336.3590g/mol
Density
1.2300g/cm3
Appearence

Berberine typically appears as a yellow crystalline powder. It is bright and intense in color, which has historically made it useful as a dye.

Comment on solubility

Solubility of 2,3-Dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium (C20H18NO4)

The solubility of 2,3-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium, with the chemical formula C20H18NO4, can be quite intriguing due to its complex structure. Here are some important points to consider regarding its solubility:

  • Solvent Dependence: This compound is likely to display differing solubility profiles depending on the solvent used. Polar solvents may enhance solubility due to potential interactions with functional groups.
  • Hydrophobic Character: The presence of multiple methoxy groups suggests a certain level of hydrophobic characteristics, potentially leading to limited solubility in water, while favoring organic solvents.
  • Temperature Influence: As with many organic compounds, increasing temperature could positively affect solubility, enabling better dissolution in suitable solvents.
  • pH Sensitivity: Given the presence of nitrogen in the structure, the solubility might also alter with changes in pH, indicating a possible protonation site that could impact its solubility in aqueous solutions.

In conclusion, while the solubility behavior of 2,3-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium is complex and dependent on various factors, it often displays selective solubility in non-polar organic solvents, rendering it less soluble in highly polar environments like water.

Interesting facts

Interesting Facts about 2,3-Dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium

This intriguing compound, known as 2,3-Dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium, belongs to a diverse class of heterocyclic compounds that have captured the attention of chemists and researchers alike. Here are some remarkable insights:

  • Complex Structure: The structure exhibits a dense network of fused rings, showcasing a fascinating architecture that is characteristic of many natural products.
  • Potential Biological Activity: Compounds of this type may exhibit interesting biological properties, including antibacterial, antifungal, and antiviral activities, making them of great interest in medicinal chemistry.
  • Fluorescent Properties: Research has suggested that similar compounds often display fluorescence, which can be valuable in various applications including biological imaging and sensing technologies.
  • Research Applications: The unique properties of this compound make it suitable for research applications in fields like photochemistry and materials science.
  • Structure-Activity Relationship Studies: The various substituents present in this compound allow chemists to explore structure-activity relationships, providing insights into how different modifications can impact biological efficacy.

In summary, 2,3-Dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium is a compound rich in complexity and potential, exemplifying the fascinating interplay of chemistry and biology. For scientists, it represents not just a chemical structure to study, but also a window into the possibilities that arise from the diverse world of organic compounds.

Synonyms
Nitidine
6872-57-7
nitidine cation
(1,3)Benzodioxolo(5,6-c)phenanthridinium, 2,3-dimethoxy-12-methyl-
2,3-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium
NSC 146397
NITIDIN
CHEBI:7578
NITIDINE ION
UNII-933301178Z
NCIMech_000542
Neuro_000081
[1,3]Benzodioxolo[5,6-c]phenanthridinium, 2,3-dimethoxy-12-methyl-
DTXSID60218846
933301178Z
[1,3]Dioxolo[4',5':4,5]benzo[1,2-c]phenanthridinium,2,3-dimethoxy-12-methyl-
2,3-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium
AC1L1IB4
2,3-Dimethoxy-12-methyl(1,3)benzodioxolo(5,6-c)phenanthridin-12-ium
2,3-dimethoxy-12-methyl-(1,3)benzodioxolo(5,6-c)phenanthridin-12-ium
CHEMBL176008
SCHEMBL8014101
DTXCID10141337
BDBM50017566
CCG-35985
AKOS015904022
NCGC00482764-03
AC-34413
NCI60_000995
C09595
E80662
Q15425772
[1,3]Benzodioxolo[5,6-c]phenanthridinium,2,3-dimethoxy-12-methyl-
2,3-Dimethoxy-12-methyl-9H-phenanthridino[4',3'-2,1]benzo[4,5-d]1,3-dioxolane