1,2-Dipalmitoylphosphatidylcholine | Solubility of Things

Identification

Molecular formula

C₄₀H₈₀NO₈P

CAS number

63-89-8

IUPAC name

2,3-di(hexadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate

State

At room temperature, 1,2-Dipalmitoylphosphatidylcholine is in a solid state. It is not soluble in water but can dissolve in organic solvents such as chloroform and methanol.

Melting point (Celsius)

66.00

Melting point (Kelvin)

339.15

Boiling point (Celsius)

300.00

Boiling point (Kelvin)

573.15

General information

Molecular weight

734.04g/mol

Molar mass

734.0360g/mol

Density

0.9878g/cm³

Appearence

1,2-Dipalmitoylphosphatidylcholine is a white to off-white waxy solid or powder. It is generally available in a purified and crystallized form, appearing as fine crystals.

Comment on solubility

Solubility of 2,3-di(hexadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate

2,3-di(hexadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate, with the chemical formula C₄₀H₈₀NO₈P, exhibits unique solubility characteristics influenced by its structure. Here are some key points regarding its solubility:

Amphiphilic Nature: This compound possesses both hydrophilic and hydrophobic regions, as it contains a phosphate group (hydrophilic) and long hexadecanoyl chains (hydrophobic). This duality often leads to interesting solubility behaviors.
Solvent Compatibility: Due to the lengthy hydrophobic chains, 2,3-di(hexadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate is expected to be soluble in non-polar solvents, such as hexane, while showing limited solubility in polar solvents like water.
Temperature Effects: The solubility may also vary with temperature; increased temperatures can enhance solubility in organic solvents due to increased kinetic energy that promotes solute-solvent interactions.
Application-Driven Solubility: In biological or pharmaceutical settings, the solubility profile is crucial for its application, especially as a surfactant or drug delivery agent. In such contexts, the balance of hydrophilic and hydrophobic portions determines *effective dosage* and *bioavailability*.

Ultimately, understanding the solubility of 2,3-di(hexadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate not only aids in its application but also enriches our knowledge of similar amphiphilic compounds.

Interesting facts

Interesting Facts about 2,3-di(hexadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate

2,3-di(hexadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate is a fascinating compound that falls within the category of phospholipids, which are essential components of biological membranes. Here are some notable points about this compound:

Biological Importance: As a phospholipid derivative, this compound plays a crucial role in forming lipid bilayers, which serve as fundamental elements of cell membranes.
Amphiphilic Nature: Its structure features both hydrophilic (water-attracting) and hydrophobic (water-repelling) sections, which enable it to interact with both aqueous environments and hydrophobic lipid layers.
Applications in Drug Delivery: Due to its unique properties, this compound is being studied for use in drug delivery systems. Its amphiphilic nature helps encapsulate pharmaceutical compounds, improving their bioavailability.
Cosmetic Uses: The compound is also explored in the cosmetic industry for formulations aimed at enhancing skin hydration and texture.
Potential in Food Science: Its surfactant properties may be beneficial in food technology, particularly in stabilizing emulsions and enhancing flavor delivery.

As science progresses, understanding the nuances and applications of compounds like 2,3-di(hexadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate will pave the way for innovations in various fields—from healthcare to cosmetic formulations. This illustrates the continuing relevance of chemistry in tackling real-world problems.

Synonyms

2644-64-6

1,2-DIPALMITOYLPHOSPHATIDYLCHOLINE

1,2-Dipalmitoyl-rac-glycero-3-phosphocholine

DL-Dipalmitoylphosphatidylcholine

2797-68-4

DL-alpha-DPPC

1,2-DIHEXADECANOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE

DL-Dipalmitoyllecithin

DPPC (phosphatide)

Coatsome MC 6060

1,2-Dipalmitoyllecithin

DL-beta,gamma-Dipalmitoyl-alpha-lecithin

beta,gamma-Dipalmitoyllecithin

DL-Dipalmitoyl-alpha-lecithin

1,2-Dipalmitoyl-DL-phosphatidylcholine

2W15RT5V7V

DL-alpha-Phosphatidylcholine, dipalmitoyl

Dihexadecanoyl phosphatidylcholine

Dipalmitoyllecithin

DL-3-Dipalmitoylphosphatidylcholine

DPPC, DL

EINECS 220-153-9

EINECS 220-530-8

rac-1,2-Dipalmitoylglycerol-3-phosphorylcholine

1,2-Dihexadecanoyl phosphatidylcholine

rac-1,2-Dipalmitoylphosphatidylcholine

1,2-Dipalmitoylglycerophosphorylcholine

1,2-Dipalmitoyl-3-phosphatidyl choline

alpha,beta-Dipalmitoylphosphatidylcholine

Dipalmitoyl-DL-alpha-phosphatidylcholine

beta,gamma-Dipalmitoyl-DL-alpha-lecithin

1,2-Dipalmitoyl-alpha-phosphatidylcholine

1-Palmitoyl-2-palmitoylphosphatidylcholine

dl-1,2-Dipalmitoyl-3-phosphatidylcholine

(+-)-beta,gamma-Dipalmitoyl-alpha-lecithin

1,2-Dipalmitoylglycerol-3-phosphorylcholine

1,2-Dipalmitoyl-DL-alpha-phosphatidylcholine

beta,gamma-Dipalmitoyl-DL-phosphatidylcholine

Choline, phosphate, ester with 1,2-dipalmitin

DIPALMITOYL LECITHIN, DL-

2,3-di(hexadecanoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate

1,2-dipalmitoyl-phosphatidylcholine

1,2-Dihexadecanoyl-rac-glycerol-3-phosphrylcholine

beta,gamma-Dipalmitoyl-DL-alpha-phosphatidylcholine

DL-beta,gamma-Dipalmitoyl-alpha-phosphatidylcholine

alpha-Glycerophosphorylcholine, beta,gamma-palmitoyl-

beta,gamma-Dipalmitoyl-DL-alpha-glycerylphosphorylcholine

1,2 Dihexadecyl sn Glycerophosphocholine

DIPALMITOYLPHOSPHATIDYLCHOLINE, DL-

1,2-DIPALMITOYLPHOSPHATIDYLCHOLINE, DL-

DIPALMITOYLPHOSPHATIDYLCHOLINE, (+/-)-

3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-((1-oxohexadecyl)oxy)-, inner salt, 4-oxide

RAC-1,2-DIPALMITOYLGLYCERO-3-PHOSPHOCHOLINE

2,3-bis(palmitoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate

Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-palmitin

Dipalmitoylglycerophosphocholine

DL-Dipalmitoyl-.alpha.-lecithin

3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-((1-oxohexadecyl)oxy)-, hydroxide, inner salt, 4-oxide

3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]-, hydroxide, inner salt, 4-oxide

.beta.,.gamma.-Dipalmitoyllecithin

L-a-Dipalmitoyl lecithin

Dipalmitoyl-DL-.alpha.-phosphatidylcholine

.alpha.,.beta.-Dipalmitoylphosphatidylcholine

1,2-Dipalmitoyl-.alpha.-phosphatidylcholine

DPPC;L-beta,gamma-Dipalmitoyl-alpha-lecithin

UNII-2W15RT5V7V

.beta.,.gamma.-Dipalmitoyl-DL-.alpha.-lecithin

DL-.beta.,.gamma.-Dipalmitoyl-.alpha.-lecithin

.beta.,.gamma.-Dipalmitoyl-DL-phosphatidylcholine

Phosphatidylcholine, Dipalmitoyl

.alpha.-Glycerophosphorylcholine, .beta.,.gamma.-palmitoyl-

.beta.,.gamma.-Dipalmitoyl-DL-.alpha.-phosphatidylcholine

DL-.beta.,.gamma.-Dipalmitoyl-.alpha.-phosphatidylcholine

Dipalmitoyl DL-a-phosphatidylcholine

.beta.,.gamma.-Dipalmitoyl-DL-.alpha.-glycerylphosphorylcholine

1,2 Dipalmitoyl Glycerophosphocholine

1,2-Dipalmitoyl-Glycerophosphocholine

MFCD00066101

1,2Dipalmitoyllecithin

1,2-Dihexadecyl-sn-Glycerophosphocholine

2,3-bis(palmitoyloxy)propyl-2-(trimethylammonio)ethylphosphat

beta,gammaDipalmitoyllecithin

DL-,-Dipalmitoyl--lecithin

DL-alpha-Phosphatidylcholine

L-alpha-dipalmitoyl lecithin

SCHEMBL184776

DTXSID50910226

HMS3370B08

1,2Dipalmitoyl3phosphatidyl choline

BCP08131

BCP30980

BNA49533

1,2Dihexadecanoyl phosphatidylcholine

1,2Dipalmitoylalphaphosphatidylcholine

1,2Dipalmitoylglycerophosphorylcholine

1Palmitoyl2palmitoylphosphatidylcholine

AKOS037653252

alpha,betaDipalmitoylphosphatidylcholine

FD15885

GS-6140

HY-W718223

(4-Oxido-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium 4-oxide

1,2Dipalmitoylglycerol3phosphorylcholine

SY057411

DB-054573

Choline, phosphate, ester with 1,2dipalmitin

alphaGlycerophosphorylcholine, beta,gammapalmitoyl

Q2587934

1,2-dipalmitoyl-sn-glycero-3-phosphocholine-1,1,2,2-d4

1,2-Dipalmitoyl-rac-glycero-3-phosphocholine;DPPC (phosphatide)

2,3-Bis(hexadecanoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate

(2-{[2,3-bis(hexadecanoyloxy)propyl phosphono]oxy}ethyl)trimethylazanium

(4Oxido10oxo7palmitoyl3,5,9trioxa4phosphapentacosyl)trimethylammonium 4oxide

1,2-DIPALMITOYL-D62-SN-GLYCERO-3-PHOSPHOCHOLINE-1,1,2,2-D4-N,N,N-TRIMETHYL-D 9

Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2dipalmitin

220-153-9

3,5,9Trioxa4phosphapentacosan1aminium, 4hydroxyN,N,Ntrimethyl10oxo7((1oxohexadecyl)oxy), hydroxide, inner salt, 4oxide