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Tricresyl phosphate

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Identification
Molecular formula
C21H21O4P
CAS number
1330-78-5
IUPAC name
2,2,2-trichloro-1-dimethoxyphosphoryl-ethanol
State
State

At room temperature, tricresyl phosphate is in a liquid state. Its appearance is typically that of a colorless to pale yellow liquid, often described as being clear and somewhat oily.

Melting point (Celsius)
-40.00
Melting point (Kelvin)
233.15
Boiling point (Celsius)
407.00
Boiling point (Kelvin)
680.15
General information
Molecular weight
368.49g/mol
Molar mass
368.4930g/mol
Density
1.4250g/cm3
Appearence

Tricresyl phosphate appears as a pale yellow, viscous liquid. It is typically clear and may appear somewhat oily in texture.

Comment on solubility

Solubility of 2,2,2-Trichloro-1-dimethoxyphosphoryl-ethanol

The solubility of 2,2,2-trichloro-1-dimethoxyphosphoryl-ethanol (C21H21O4P) is influenced by several factors due to its unique structural characteristics. Overall, this compound exhibits moderate solubility in various solvents. Here are some key considerations regarding its solubility:

  • Polar vs. Non-Polar Solvent Behavior: The presence of the dimethoxy and phosphoryl groups in the molecule makes it relatively polar, suggesting that it will be more soluble in polar solvents such as water or alcohols.
  • Hydrophobic Interactions: Despite the polar aspects, the trichloro substitution adds some hydrophobic character to the compound, which may reduce its solubility in purely polar solvents.
  • Temperature Influence: Like many organic compounds, solubility of this compound can vary with temperature; typically, higher temperatures promote enhanced dissolution rates.

In summary, while 2,2,2-trichloro-1-dimethoxyphosphoryl-ethanol has some degree of solubility, its overall behavior will depend on the solvent choice and environmental conditions. The balance between its polar and non-polar regions plays a significant role in dictating its solubility profile, making it a compound of interest in solubility studies.

Interesting facts

Interesting Facts about 2,2,2-Trichloro-1-dimethoxyphosphoryl-ethanol

2,2,2-Trichloro-1-dimethoxyphosphoryl-ethanol is a fascinating chemical compound that falls under the category of organophosphorus compounds. Here are some appealing insights:

  • Versatile Chemical Backbone: This compound contains a phosphorus atom bound to chlorine and methoxy groups, making it significant in the realm of chemistry due to its versatility in different chemical reactions.
  • Role in Synthesis: It is often used as an intermediate in organic synthesis, particularly in the development of agrochemicals and pharmaceuticals. Its unique structure allows it to participate in various chemical transformations.
  • Biological Activity: The presence of chlorine and phosphorus atoms highlights its potential biological activity, which has sparked interest among chemists and biologists alike for its possible applications in drug development.
  • Environmental Considerations: Due to its organophosphorus nature, there are important environmental considerations regarding its use and disposal. Chemists study its behavior in the environment to minimize detrimental effects.
  • Spectroscopy Delight: This compound’s structure lends itself well to analysis via various spectroscopic methods, including NMR and IR spectroscopy, which allow scientists to observe its molecular dynamics and interactions.

The complexity and utility of 2,2,2-trichloro-1-dimethoxyphosphoryl-ethanol make it a subject of study that bridges multiple fields, showcasing the interconnectedness of chemistry, biology, and environmental science. As one researcher noted, "Understanding such compounds reveals the intricate dance of atoms that facilitates life and technology."

Synonyms
TRICHLORFON
Metrifonate
Chlorophos
52-68-6
Metriphonate
Trichlorphon
Methyl chlorophos
Trichlorofon
Chloroxyphos
Bilarcil
Chlorofos
Chloroftalm
Dylox
DETF
Chlorophthalm
Fliegenteller
Trichlorophon
Agroforotox
Dipterex
Diptevur
Ditrifon
Foschlor
Hypodermacid
Khloroftalm
Metrifonatum
Phoschlor
Polfoschlor
Ritsifon
Volfartol
Anthon
Bovinox
Briten
Briton
Cekufon
Combot
Forotox
Loisol
Masoten
Mazoten
Neguvon
Proxol
Ricifon
Soldep
Sotipox
Trinex
Votexit
Wotexit
Danex
Dyrex
Dyvon
Tugon
Trichlorphon FN
(+-)-Trichlorfon
Equino-Aid
Foschlor R
Chlorophosciclosom
Flibol E
Bayer L 1359
DEP (pesticide)
Foschlorem
Metrifonato
Trichloorfon
Chlorak
Clorofos
Denkaphon
Dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate
Dimetox
Dioxaphos
Dipterex 50
Phoschlor R50
Metriphonatum
Chlorfos
Chlorphos
Ciclosom
Leivasom
Britten
Depthon
Dipterex WP 80
Foschlor R-50
Combot equine
Dicontal Fort
Tugon fly bait
Dipterex SL
Ditriphon 50
Tugon stable spray
Foschlor 25
Aerol 1
WEC 50
Trichlorophone
BAY-a 9826
Bayer L 13/59
Dipterax
Metifonate
Trichlorfon [USAN]
Triclorfon
Satox 20WSC
Aerol 1 (pesticide)
Caswell No. 385
NCI-C54831
Vermicide bayer 2349
BAY 15922
ENT 19,763
Bayer 15922
OMS 800
BAY-L 1359
1-Hydroxy-2,2,2-trichloroethylphosphonic acid dimethyl ester
CCRIS 1289
HSDB 881
Neguron
Onefon
Phosphonic acid, (2,2,2-trichloro-1-hydroxyethyl)-, dimethyl ester
UNII-DBF2DG4G2K
Bayer-L-1359
DBF2DG4G2K
Metrifonatum [INN-Latin]
Metrifonato [INN-Spanish]
NSC 8923
NSC-8923
(+)-Trichlorfon
(-)-Trichlorfon
EINECS 200-149-3
EPA Pesticide Chemical Code 057901
Foschlor R 50
Metrifonate [INN]
Dimethyltrichlorohydroxyethyl phosphonate
BRN 1709434
CHEBI:6908
WEC-50
Dimethyl 2,2,2-trichloro-1-hydroxyethylphosphonate
DTXSID0021389
Metrifonate, (+)-
Metrifonate, (-)-
AI3-19763
Dimethyl (1-hydroxy-2,2,2-trichloroethyl)phosphonate
O,O-Dimethyl-1-oxy-2,2,2-trichloroethyl phosphonate
O,O-Dimethyl (1-hydroxy-2,2,2-trichloroethyl)phosphonate
O,O-Dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate
(2,2,2-Trichloro-1-hydroxyethyl)phosphonic acid dimethyl ester
ENT-19,763
O,O-Dimethyl-(1-hydroxy-2,2,2-trichloraethyl)phosphosaeure ester
Phosphonic acid, (1-hydroxy-2,2,2-trichloroethyl)-, dimethyl ester
1MVY4KU98F
37VCQ9C0OG
Dimethyl 1-hydroxy-2,2,2-trichloroethyl phosphonate
Dimethyl(2,2,2-trichloro-1-hydroxyethyl)phosphonate
O,O-Dimethyl (1-oxy-2,2,2-trichloroethyl)phosphonate
O,O-Dimethyl-(1-hydroxy-2,2,2-trichlorathyl)-phosphat
O,O-Dimethyl-1-hydroxy-2,2,2-trichloroethylphosphonate
O,O-Dimetil-(2,2,2-tricloro-1-idrossi-etil)-fosfonato
MLS000069726
1-Hydroxy-2,2,2-trichloro-ethyle phosphonate de dimethyle
CHEMBL167150
Dimethoxy-2,2,2-trichloro-1-hydroxy-ethyl phosphine oxide
Dimethoxy-2,2,2-trichloro-1-hydroxy-ethyl-phosphine oxide
DTXCID701389
O,O-Dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosponate
O,O-Dimethyl-(2,2,2-trichloor-1-hydroxy-ethyl)-fosfonaat
O,O-Dimethyl-(2,2,2-trichlor-1-hydroxy-aethyl)phosphonat
2,2,2-trichloro-1-dimethoxyphosphorylethanol
(2,2,2-Trichloro-1-hydroxyethyl)-phosphonic acid dimethyl ester
O,O Dimetil 2,2,2-trichloro 1 hidroxietil fosfonato (Portugese)
Trichlorfon (USAN)
NCGC00018237-03
SMR000058176
Dimethyl (trichlorohydroxyethyl)phosphonate
O,O-Dimethyl-(1-hydroxy-2,2,2-trichloraethyl)phosphonsaeure ester
Metrifonatum (INN-Latin)
TRICHLORFON (IARC)
TRICHLORFON [IARC]
Metrifonato (INN-Spanish)
METRIFONATE (MART.)
METRIFONATE [MART.]
TRICHLORFON (USP-RS)
TRICHLORFON [USP-RS]
26373-97-7
56042-27-4
Dimethyl 1-hydroxy-2,2,2-trichloroethylphosphonate
Foschlorem [Polish]
Trichlorphon [ISO]
Trichloorfon [Dutch]
Trichlorfon [German]
METRIFONATE (EP IMPURITY)
METRIFONATE [EP IMPURITY]
trichlorphene
METRIFONATE (USP IMPURITY)
METRIFONATE [USP IMPURITY]
METRIFONATE (USP MONOGRAPH)
METRIFONATE [USP MONOGRAPH]
DIMETHYL (P)-(2,2,2-TRICHLORO-1-HYDROXYETHYL)PHOSPHONATE
DIMETHYL (RS)-2,2,2-TRICHLORO-1-HYDROXYETHYLPHOSPHONATE
Trichlorfon [BSI:ISO]
Phosphonic acid, (2,2,2-trichloro-1-hydroxyethyl)-, dimethyl ester, (+)-
Phosphonic acid, (2,2,2-trichloro-1-hydroxyethyl)-, dimethyl ester, (-)-
Phosphonic acid, P-(2,2,2-trichloro-1-hydroxyethyl)-, dimethyl ester, (+)-
Phosphonic acid, P-(2,2,2-trichloro-1-hydroxyethyl)-, dimethyl ester, (-)-
Foschlor R-50 (VAN)
56042-26-3
Clorofos [Russian]
Chlorophose
Foschlorine
Ditrofon
Ertefon
Memobay
Zeltivar
ProMem
Metrifonate; Dimethyl (RS)-(2,2,2-trichloro-1-hydroxyethyl)phosphonate; Trichlorfon
CAS-52-68-6
Dylox-metasystox-R
Phoschlor R.50
Prestwick_599
Totalene (Salt/Mix)
(+/-)-Trichlorfon
EQUINO-ACID
TRI CHLORFON
NEGUVON A
starbld0043468
Opera_ID_345
Bayer 2349
Metrifonate (USP/INN)
TRICHLORFON [MI]
1-Hydroxy-2,2,2-trichloro-ethyle phosphonate de dimethyle [French]
O,O-Dimethyl-(1-hydroxy-2,2,2-trichlorathyl)-phosphat [German]
O,O-Dimethyl-(2,2,2-trichloor-1-hydroxy-ethyl)-fosfonaat [Dutch]
O,O-Dimethyl-(2,2,2-trichlor-1-hydroxy-aethyl)phosphonat [German]
O,O-Dimetil-(2,2,2-tricloro-1-idrossi-etil)-fosfonato [Italian]
Prestwick0_000051
Prestwick1_000051
Prestwick2_000051
Prestwick3_000051
DYLOX-METASYSTOX R
TRICHLORFON [ISO]
(.+/-.)-Trichlorfon
TRICHLORFON [HSDB]
UNII-1MVY4KU98F
UNII-37VCQ9C0OG
O,O-Dimethyl-(1-hydroxy-2,2,2-trichloraethyl)phosphonsaeure ester [German]
cid_5853
Bay-a-9826
Dyrex Bolus, Dyrex Granules
SCHEMBL15972
BSPBio_000201
METRIFONATE [WHO-DD]
METRIFONATE [WHO-IP]
SPBio_002122
WLN: GXGGYQPO&O1&O1
BPBio1_000223
O,2,2-trichlorathyl)-phosphat
O,2,2-trichloroethyl)phosphate
TRICHLORFON [GREEN BOOK]
BAYER 13/59
NSC8923
P02BB01
HMS1568K03
HMS2095K03
Pharmakon1600-01505765
HY-B1220
METRIFONATUM [WHO-IP LATIN]
P-(2,2,2-Trichloro-1-hydroxyethyl)phosphonic acid dimethyl ester
Tox21_110843
Tox21_201607
Tox21_300860
BDBM50286920
MFCD00055272
NSC759241
Phosphonic acid, (2,2,2-trichloro-1-hydroxyethyl)-,dimethyl ester
AKOS001499170
AKOS022032084
Tox21_110843_1
CCG-213546
CS-4845
DB11473
NSC-759241
O,2,2-trichlorohydroxyethyl)phosphonate
USEPA/OPP Pesticide Code: 057901
2,2,2-Trichloroethyl dimethyl phosphate
NCGC00018237-02
NCGC00018237-04
NCGC00018237-06
NCGC00018237-07
NCGC00018237-09
NCGC00089822-02
NCGC00089822-03
NCGC00254763-01
NCGC00259156-01
O,2,2-trichloraethyl)phosphosaeure ester
DA-55441
FT159085
O,2,2-tricloro-1-idrossi-etil)-fosfonato
SBI-0206912.P001
Trichlorfon 100 microg/mL in Acetonitrile
0,2,2-trichloro-1-hydroxyethyl)phosphonate
O,2,2-trichloro-1-hydroxyethyl)phosphonate
NS00010188
O,2,2-trichloor-1-hydroxy-ethyl)-fosfonaat
O,2,2-trichlor-1-hydroxy-aethyl)phosphonat
C07971
D00805
F21293
Trichlorfon, PESTANAL(R), analytical standard
Q422991
SR-01000000181
Dimethyl (1-hydroxy-2,2-trichloroethyl)phosphonate
Dimethyl (2,2,2-trichlorohydroxyethyl) phosphonate
Dimethyl (2,2-trichloro-1-hydroxyethyl)phosphonate
SR-01000000181-2
(2,2,2-Trichloro-1-hydroxyethyl) dimethylphosphonate
[(2,2-Trichloro-1-hydroxyethyl) dimethylphosphonate]
BRD-A22101059-001-13-0
BRD-A22101059-001-14-8
O,O-Dimethyl (2,2,2-trichlorohydroxyethyl)phosphonate
O,O-dimethyl 1-oxy-2,2,2-trichloroethyl phosphonate
Phosphonic acid,2,2-trichloroethyl)-, dimethyl ester
trichloro-alpha-hydroxyethyl phosphonic dimethyl ester
((2,2,2-Trichloro-1-hydroxyethyl) dimethylphosphonate)
1-Hydroxy-2,2-trichloro-ethyle phosphonate de dimethyle
Dimethoxy-(2,2-trichloro-1-hydroxyethyl)phosphine oxide
O,O-Dimethyl (1-hydroxy-2,2,2-trichloroethyl)phosphate
o,o-dimethyl-2,2,2-trichloro-1-hydroxyethyl phosphonate
(2,2-Trichloro-1-hydroxy)phosphonic acid, dimethyl ester
(2,2-Trichloro-1-hydroxyethyl)phosphonate, dimethyl ester
Dimethoxy-(2,2,2-trichloro-1-hydroxyethyl)phosphine oxide
DIMETHYL-1-HYDROXY-2,2,2-TRICHLOROETHYL PHOSPHONATE
Metrifonate, European Pharmacopoeia (EP) Reference Standard
O,O-Dimethyl(2,2,2-tri-chloro-1-hydroxyethyl)phosphonate
O,O-Dimethyl-(1-hydroxy-2,2,2-trichloro)ethyl phosphate
O,O-Dimethyl-(2,2,2-trichloro-1-idrossi-etil)-fosfonato
(1-Hydroxy-2,2-trichloroethyl)phosphonic acid, dimethyl ester
(2,2,2-Trichloro-1-hydroxyethyl)phosphonate, dimethyl ester
(2,2-Trichloro-1-hydroxyethyl)phosphonic acid dimethyl ester
1-Hydroxy-2,2,2-trichloroethylphosphonate-O,O-dimethyl ester
DIMETHOXY-2,2,2-TRICHLORO-1-HYDROXYETHYLPHOSPHINE OXIDE
O,O-dimethyl 1 (2,2,2-trichloro-1-hydroxyethyl)-phosphonate
PHOSPHONIC ACID, (2,2,2-TRICHLORO-1-HYDROXYETHYL)-,DI
Phosphonic acid,2,2-trichloro-1-hydroxyethyl)-, dimethyl ester
(1-Hydroxy-2,2,2-trichloroethyl)phosphonic acid, dimethyl ester
2,2,2-TRICHLORO-1-HYDROXYETHYL-PHOSPHONATE, DIMETHYL ESTER
2,2-TRICHLORO-1-HYDROXYETHYL)PHOSPHONIC ACID, DIMETHYL ESTER
O,O-DIMETHYL(1-HYDROXY-2,2,2-TRICHLOROETHYL)PHOSPHONATE
Trichlorfon, United States Pharmacopeia (USP) Reference Standard
(2,2,2-TRICHLORO-1-HYDROXYETHYL)PHOSPHONIC ACID, DIMETHYL ESTER
Metrifonate;(2,2,2-Trichloro-1-hydroxyethyl)phosphonic acid dimethyl ester
Phosphonic acid, P-(2,2,2-trichloro-1-hydroxyethyl)-, dimethyl ester
InChI=1/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H
200-149-3