Interesting facts
Interesting Facts about 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide is a compound that garners attention due to its intriguing structure and potential applications. Here are some noteworthy points regarding this chemical:
- Structural Characteristics: The compound features a dichloroacetamide backbone, highlighting the incorporation of two chlorine atoms which significantly influence its reactivity and biological activity.
- Chiral Center: The presence of a chiral center in the molecule not only makes it optically active but may also lead to stereospecific interactions with biological receptors.
- Biological Relevance: Compounds similar to this structure have been studied for their potential as therapeutic agents and may play a role in inhibiting specific biological pathways or processes.
- 4-Nitrophenyl Group: The inclusion of a 4-nitrophenyl moiety adds substantial electronic effects to the compound, influencing its overall chemical behavior and making it a candidate for further research in fields such as medicinal chemistry.
- Functional Groups: The hydroxymethyl and hydroxy groups present in its structure are crucial for its reactivity. They can participate in hydrogen bonding, which might affect solubility and interaction with biomolecules.
As stated by chemist and author Linus Pauling, "The science of chemistry is the study of the properties of matter and how matter changes." In exploring compounds like this, we expand our understanding of how structural variations can lead to diverse properties and functions. The investigation of this compound could contribute to advancements in pharmaceutical development, highlighting the bridge between theoretical chemistry and practical applications.
Synonyms
chloramphenicol
56-75-7
Chloromycetin
Chlornitromycin
Levomycetin
Chloroamphenicol
Globenicol
Halomycetin
Levomicetina
Oleomycetin
Alficetyn
Chloramex
Chlorocid
Chlorocol
Fenicol
Chloramficin
Chloramfilin
Enteromycetin
Amphicol
Aquamycetin
Chloroptic
Cloramicol
D-Chloramphenicol
Detreomycin
Econochlor
Juvamycetin
Novomycetin
Sificetina
Mychel
Chloramphenicolum
Amphenicol
Austracil
Austracol
Biophenicol
Chemicetin
Chemicetina
Chlomycol
Chloramsaar
Chlorasol
Chloricol
Chlorocaps
Chlorocide
Chloronitrin
Chlorovules
Cidocetine
Ciplamycetin
Cloramficin
Cloramidina
Cloromisan
Clorosintex
Comycetin
Cylphenicol
Detreomycine
Doctamicina
Embacetin
Erbaplast
Farmicetina
Hortfenicol
Intramycetin
Ismicetina
Isophenicol
Kemicetina
Kemicetine
Laevomycetinum
Leukomyan
Leukomycin
Levomitsetin
Loromisin
Mastiphen
Mediamycetine
Micloretin
Micochlorine
Micoclorina
Microcetina
Novophenicol
Ophthochlor
Rivomycin
Stanomycetin
Synthomycetin
Ambofen
Amseclor
Anacetin
Biocetin
Catilan
Chlomin
Clorocyn
Desphen
Emetren
Ertilen
Glorous
Isicetin
Kamaver
Klorita
Enicol
Isopto fenicol
Chlora-tabs
Chlorocidin C
Chloroject L
Normimycin V
Klorocid S
Mychel-Vet
Chloramfenikol
Cloramfenicol
Novochlorocap
Pentamycetin
Sintomicetina
Chloromax
Medichol
Oftalent
Otachron
Pantovernil
Quemicetina
Romphenil
Ronphenil
Septicol
Mycinol
Opclor
Otophen
Paraxin
Chloro-25 vetag
Sintomicetine R
Sno-Phenicol
Chlorocid S
Chlorocidin C tetran
Cloroamfenicolo
Chlorofair
Optomycin
D-(-)-Chloramphenicol
Chloromycetny
Cloranfenicol
Tifomycine
Treomicetina
Unimycetin
Tevcocin
Veticol
Viceton
Dextromycetin
Synthomycetine
CAF (pharmaceutical)
D-(-)-threo-Chloramphenicol
Chloramphenicol crystalline
Chloramphenicol, d-
I 337A
Synthomycine
Tiromycetin
Leukamycin
Loromisan
Tifomycin
NCI-C55709
D-threo-Chloramphenicol
NSC 3069
Tega-Cetin
U-6062
2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
Cloramfenicol [INN-Spanish]
Chloramphenicolum [INN-Latin]
CCRIS 3922
D-(-)-threo-1-p-Nitrophenyl-2-dichloroacetylamino-1,3-propanediol
CHEBI:17698
HSDB 3027
Chloramphenicol-[ring-3,5-3H]
NSC3069
2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
NSC-3069
D(-)-threo-Chloramphenicol
CAF
EINECS 200-287-4
Cloramfen
BRN 2225532
D-(-)-2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenylethyl)acetamide
Chloramphenicol (Chloromycetin)
Ak-chlor
125440-98-4
D-(-)-threo-1-p-Nitrophenyl-2-dichloracetamido-1,3-propanediol
DTXSID7020265
UNII-66974FR9Q1
AI3-25003
Acetamide, 2,2-dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-, (R-(R*,R*))-
MFCD00078159
66974FR9Q1
D-(-)-threo-2-Dichloroacetamido-1-p-nitrophenyl-1,3-propanediol
D-(-)-threo-1-(4-Nitrophenyl)-2-dichloroacetamido-1,3-propanediol
D-threo-(1R,2R)-1-p-Nitrophenyl-2-dichloroacetamido-1,3-propanediol
DTXCID90265
Cloramfenicolo
Kloramfenikol
Syntomycin
D-threo-N-(1,1'-Dihydroxy-1-p-nitrophenylisopropyl)dichloroacetamide
4-13-00-02742 (Beilstein Handbook Reference)
Chloramphenicol [USP:INN:BAN:JAN]
Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [R-(R*,R*)]-
NCGC00091011-05
OPHTHOCORT COMPONENT CHLORAMPHENICOL
D(-)-threo-2-Dichloroacetamido-1-p-nitrophenyl-1,3-propanediol
CHLOROMYXIN COMPONENT CHLORAMPHENICOL
D-threo-N-Dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propanediol
Chloramfenikol [Czech]
Chloramphenicol 10 microg/mL in Acetonitrile
Chloromycetny [Polish]
Cloramfenicolo [DCIT]
2,2-Dichloro-N-((1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl)acetamide
C11H12Cl2N2O5
Chlorbiotic (Veterinary)
Chloramphenicol 100 microg/mL in Ethyl acetate
Acetamide, 2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)-, D-(-)-threo-
Cloroamfenicolo [Italian]
D-threo-(-)-2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide
Cloramfenicol (INN-Spanish)
Elase-Chloromycetin
Gloveticol
Mycochlorin
Ocuphenicol
Sintomicetin
Tyfomycine
Chlorocin
Halcetin
Levocin
Levoplast
Levosin
Levovetin
Myclocin
Soluthor
Acetamide, 2,2-dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-, (theta-(theta,theta))-
ELASE-CHLOROMYCETIN COMPONENT CHLORAMPHENICOL
CHLORAMPHENICOL (IARC)
CHLORAMPHENICOL [IARC]
Chloramphenicolum (INN-Latin)
Chloroptic S.O.P.
CHLORAMPHENICOL (MART.)
CHLORAMPHENICOL [MART.]
CHLORAMPHENICOL (USP-RS)
CHLORAMPHENICOL [USP-RS]
Ophtochlor
Tevcosin
Opelor
D-(-)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol
D-threo-1-(p-Nitrophenyl)-2-(dichloroacetylamino)-1,3-propanediol
(-)-chloramphenicol
CHLORAMPHENICOL (EP MONOGRAPH)
Chloramphenicol (USP:INN:BAN:JAN)
CHLORAMPHENICOL [EP MONOGRAPH]
CHLORAMPHENICOL (USP MONOGRAPH)
CHLORAMPHENICOL [USP MONOGRAPH]
2,2-DICHLORO-N-((1R,2R)-2-HYDROXY-1-(HYDROXYMETHYL)-2-(4-NITROPHENYL)ETHYL)ACETAMIDE
2,2-Dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)-2-propyl]acetamide
Acetamide, 2,2-dichloro-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-
Econochlor (TN)
Amphicol (TN)
Ophthocort (Salt/Mix)
ACETAMIDE, 2,2-DICHLORO-N-[(1R,2R)-2-HYDROXY-1-(HYDROXYMETHYL)-2-(4-NITROPHENYL)ETHYL]-
SMR000471851
Chloromyxin (Salt/Mix)
Chloromycetin (TN)
SR-01000761450
Elase-Chloromycetin (Salt/Mix)
chioramphenicol
Petnamycetin
Chloramphenicol & VRC3375
Chloramphenicole
Chloro mycetin
Chloro vules
Cloro sintex
Hort fenicol
Viceton Tablets
Chlor asol
Anacetin Tablets
Medichol Tablets
Norimycin V
Mychel-Vet Tabs
CAS-56-75-7
NCGC00094620-01
Thiamphenicol,(S)
D-(-)-threo-2,2-Dichloro-N-(.beta.-hydroxy-.alpha.-(hydroxymethyl))-p-nitrophenethylacetamide
D-(-)-threo-2,2-Dichloro-N-[.beta.-hydroxy-.alpha.-(hydroxymethyl)]-p-nitrophenethylacetamide
Chloramphenicol,(S)
Mychel-Vet Injection
2,2-Dichloro-N-
Chloramphenicol Capsules
Prestwick3_000031
Chloramphenicol (Standard)
CHEMBL130
Epitope ID:114066
Pork muscle-Chloramphenicol
CHLORAMPHENICOL [MI]
SCHEMBL16111
BSPBio_000121
CHLORAMPHENICOL [INN]
CHLORAMPHENICOL [JAN]
WLN: WNR DYQY1QMVYGG
MLS001055372
MLS001066397
MLS001332385
MLS001332386
MLS002222155
BIDD:GT0145
CHLORAMPHENICOL [HSDB]
DivK1c_000544
CHLORAMPHENICOL [VANDF]
BPBio1_000135
Mychel-Vet Capsules (50 mg)
CHLORAMPHENICOLUM [HPUS]
CHLORAMPHENICOL [WHO-DD]
CHLORAMPHENICOL [WHO-IP]
D-(-)-threo-1-(p-Nitrophenyl)-2-(dichloroacetylamino)-1,3-propanediol
D-(-)-threo-N-Dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propanediol
BDBM23447
Chloramphenicol, gamma-irradiated
Chloromycetin Ophthalmic Ointment
GTPL10901
HMS501L06
HY-B0239R
KBio1_000544
MSK7001
NINDS_000544
754 - Chloramphenicol in seafood
Chloramphenicol (JP18/USP/INN)
HMS2090M15
HMS2095G03
HMS2269N06
HMS3712G03
Chloramphenicol, >=98% (HPLC)
2787-09-9
Acetamide, 2,2-dichloro-N-(.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenethyl)-, D-(-)-threo-
Acetamide, 2,2-dichloro-N-[.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenethyl]-, D-threo-(-)-
BCP12150
D-(-)-threo-2,2-Dichloro-N-(.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenyl-ethyl)acetamide
HY-B0239
RKL10087
CHLORAMPHENICOL [GREEN BOOK]
Tox21_111306
Tox21_400061
CHLORAMPHENICOL [ORANGE BOOK]
s1677
AKOS005111001
Chloramphenicol for peak identification
Porcine muscle-Chloramphenicol (blank)
AC09460
CCG-220031
DB00446
CHLORAMPHENICOLUM [WHO-IP LATIN]
IDI1_000544
SMP1_000065
NCGC00091011-01
NCGC00091011-02
NCGC00091011-03
NCGC00091011-04
NCGC00091011-06
NCGC00091011-08
NCGC00091011-09
NCGC00091011-20
AS-14683
NCI60_002620
Chloramphenicol, puriss., 98.0-102.0%
AB00374860
C2255
Chloramphenicol, tested according to Ph.Eur.
NS00000500
SW198497-2
CHLORAMPHENICOL COMPONENT OF OPHTHOCORT
C00918
CHLORAMPHENICOL COMPONENT OF CHLOROMYXIN
D00104
AB00374860-13
AB00374860-14
AB00374860_15
Chloramphenicol, meets USP testing specifications
Q274515
Chloramphenicol, VETRANAL(TM), analytical standard
SR-01000761450-2
SR-01000761450-3
SR-01000761450-5
BRD-K08111712-001-02-7
BRD-K08111712-001-14-2
BRD-K08111712-001-16-7
CHLORAMPHENICOL COMPONENT OF ELASE-CHLOROMYCETIN
CHLOROPTIC-P S.O.P. COMPONENT CHLORAMPHENICOL
Z2065671241
Chloramphenicol, BioReagent, suitable for plant cell culture
Chloramphenicol, certified reference material, TraceCERT(R)
CHLOROMYCETIN HYDROCORTISONE COMPONENT CHLORAMPHENICOL
724 - Chloramphenicol, Florfenicol, Thiamphenicol in chicken
Chloramphenicol, British Pharmacopoeia (BP) Reference Standard
Chloramphenicol, European Pharmacopoeia (EP) Reference Standard
Chloramphenicol 1% Ophthalmic, Vetrocloricin Ophthalmic Ointment
Chloramphenicol, United States Pharmacopeia (USP) Reference Standard
Acetamide,2-dichloro-N-[.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenethyl]
Chloramphenicol, Biotechnology Performance Certified, suitable for plant cell culture
Chloromycetin Tablets 100 mg, Chloromycetin Tablets 250 mg, Chloromycetin Tablets 500 mg
d(-)-threo-2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxy methyl))- p-nitrophenethylacetamide
D-(-)-2,2-Dichloro-N-(.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenyl-ethyl)acetamide
D-threo-2,2-Dichloro-N-[beta-hydroxy-alpha-(hydroxymethyl)-4-nitrophenethyl]acetamide
2,2-Dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-(hydroxy(oxido)amino)phenyl)ethyl)acetamide, (1R, 2R)-
200-287-4
Acetamide, 2,2-dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-, (R*,R*)-(+-)-
Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4- nitrophenyl)ethyl]-, [R-(R*,R*)]-
Acetamide,2-dichloro-N-[.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenethyl]-, D-threo-(-)-
Acetamide,2-dichloro-N-[.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenethyl]-,D-(-)-threo-
Acetamide,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [R-(R*,R*)]-
Chloromycetin;2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophen yl)ethyl]acetamide;D-(-)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1 ,3-propanediol
D-(-)-threo-2,2-Dichloro-N-[beta-hydroxy-alpha-(hydroxymethyl)-beta-(4-nitrophenyl)ethyl]acetamide
D-(-)-threo-alpha, alpha-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide
D-THREO-(-)-2,2-DICHLORO-N-(.BETA.-HYDROXY-.ALPHA.-(HYDROXYMETHYL)-P-NITROPHENETHYL)ACETAMIDE
DL-Chloramphenicol; Acetamide, 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, rel-; Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, (R*,R*)-(+/-)-; Acetamide, 2,2-dichloro-N-[ss-hydroxy-a-(hydroxymethyl)-p-nitrophe
Solubility of 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
The solubility of 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide (C14H16Cl2N2O4) can be influenced by a variety of factors. Understanding the solubility characteristics is essential for applications in pharmaceuticals and chemical processes.
Factors Affecting Solubility:
In summary, although the exact solubility of 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide will depend on the specific solvent and conditions used, its structural features suggest a level of moderate solubility in polar solvents. Emphasizing these properties can be crucial for developing formulations and understanding the behavior of this compound in different environments.