Bispidine | Solubility of Things

Identification

Molecular formula

C₁₀H₁₈N₂O₂

CAS number

6837-77-2

IUPAC name

2,2-bis(hydroxymethyl)-1,4-dimethyl-piperidin-3-one

State

At room temperature, bispidine is in a solid state, most commonly forming as a crystalline powder.

Melting point (Celsius)

91.00

Melting point (Kelvin)

364.15

Boiling point (Celsius)

170.00

Boiling point (Kelvin)

443.15

General information

Molecular weight

172.24g/mol

Molar mass

172.2380g/mol

Density

1.1500g/cm³

Appearence

Bispidine is typically a white or off-white crystalline solid.

Comment on solubility

Solubility of 2,2-bis(hydroxymethyl)-1,4-dimethyl-piperidin-3-one

The solubility of 2,2-bis(hydroxymethyl)-1,4-dimethyl-piperidin-3-one, with the chemical formula C₁₀H₁₈N₂O₂, is influenced by several factors that can enhance or hinder its ability to dissolve in various solvents. Here are some key aspects to consider:

Polarity: The presence of hydroxymethyl groups in the molecule imparts significant polarity, suggesting a favorable interaction with polar solvents like water.
Saturation: The molecule's structure, being relatively large and branched, may lead to decreased solubility in non-polar environments.
Hydrogen Bonding: The -OH groups will facilitate hydrogen bonding with water molecules, further promoting solubility in aqueous conditions.
Temperature's Role: Stability and solubility can be dependent on temperature; an increase often leads to enhanced solvation.

It is noteworthy that "like dissolves like", therefore:

This compound is more likely to dissolve in polar solvents.
It may show limited solubility in non-polar solvents.

Understanding these factors can provide valuable insights into the behavior of 2,2-bis(hydroxymethyl)-1,4-dimethyl-piperidin-3-one in different chemical environments.

Interesting facts

Interesting Facts about 2,2-bis(hydroxymethyl)-1,4-dimethyl-piperidin-3-one

The compound 2,2-bis(hydroxymethyl)-1,4-dimethyl-piperidin-3-one is a fascinating member of the piperidine family, a class of cyclic amines that often exhibit interesting biological activity. Here are some points that highlight the significance and versatility of this compound:

Versatile Synthetic Intermediate: This compound serves as an essential building block in organic synthesis, particularly in the creation of pharmaceuticals and agrochemicals. Its structure allows for various chemical modifications, making it a key player in drug development.
Biological Applications: Due to its unique functional groups, compounds similar to 2,2-bis(hydroxymethyl)-1,4-dimethyl-piperidin-3-one often exhibit significant bioactivity. Research continues to explore how variations of this compound can be utilized for medicinal purposes.
Hydroxymethyl Groups: The presence of hydroxymethyl groups in this compound enhances its solubility in various solvents and can influence its reactivity, making it an interesting subject for chemists studying reaction mechanisms.
Piperidine Ring System: The piperidine ring is known for its presence in numerous natural products and drugs. Understanding how modifications to the piperidine structure, like those seen in this compound, can affect biological interactions is a key area of research.
Research Interest: Ongoing studies are being conducted to fully elucidate the properties of this compound. Scientists are keen to understand its potential roles in both synthetic chemistry and biological systems.

In summary, 2,2-bis(hydroxymethyl)-1,4-dimethyl-piperidin-3-one exemplifies how structural characteristics can influence chemical behavior and application. Its rich potential not only highlights the importance of understanding molecular structure but also encourages further exploration in both academic and industrial settings.