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Paclitaxel

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Identification
Molecular formula
C47H51NO14
CAS number
33069-62-4
IUPAC name
21-hydroxy-10-isopropyl-11,19-dimethyl-9,26-dioxa-3,15,28-triazatricyclo[23.2.1.03,7]octacosa-1(27),6,12,17,19,25(28)-hexaene-2,8,14,23-tetrone
State
State

Paclitaxel is generally found in a solid state at room temperature, appearing as a crystalline powder.

Melting point (Celsius)
213.00
Melting point (Kelvin)
486.00
Boiling point (Celsius)
239.00
Boiling point (Kelvin)
512.00
General information
Molecular weight
853.91g/mol
Molar mass
853.9060g/mol
Density
1.4500g/cm3
Appearence

Paclitaxel appears as a white to off-white crystalline powder. It is practically insoluble in water, but soluble in a variety of organic solvents including methanol, ethanol, chloroform, and acetone.

Comment on solubility

Solubility of 21-hydroxy-10-isopropyl-11,19-dimethyl-9,26-dioxa-3,15,28-triazatricyclo[23.2.1.03,7]octacosa-1(27),6,12,17,19,25(28)-hexaene-2,8,14,23-tetrone (C47H51NO14)

The solubility of this complex organic compound is influenced by a variety of factors, including its molecular structure and polarity. Here are some key considerations regarding its solubility:

  • Polarity: Due to the presence of multiple functional groups and heteroatoms such as nitrogen and oxygen, the compound may exhibit polar characteristics, enhancing its interaction with polar solvents like water.
  • Hydrophobic Interactions: The significant hydrocarbon portion of the molecule suggests hydrophobic characteristics, which may limit solubility in polar solvents.
  • Solvent Choice: It is likely to have improved solubility in organic solvents such as dimethyl sulfoxide (DMSO), ethanol, or acetone, where its structure allows better solvation.
  • Temperature Dependency: Solubility can vary significantly with temperature; thus, solubility tests should include a temperature range to determine effective solubility conditions.

In summary, the solubility of C47H51NO14 is a complex interplay of its chemical structure and the solvent environment. As emphasized in the study of solubility, “Like dissolves like,” which means polar compounds typically dissolve in polar solvents, while nonpolar compounds prefer nonpolar solvents. Therefore, researchers should carefully evaluate the appropriate conditions for dissolving this compound for practical applications.

Interesting facts

Interesting Facts about 21-Hydroxy-10-isopropyl-11,19-dimethyl-9,26-dioxa-3,15,28-triazatricyclo[23.2.1.03,7]octacosa-1(27),6,12,17,19,25(28)-hexaene-2,8,14,23-tetrone

This complex compound, with its intricate structure, belongs to a class of organic molecules characterized by unique properties and potential applications. Here are some intriguing aspects of this fascinating compound:

  • Structural Complexity: The name alone reveals its intricate architecture, featuring multiple functional groups and a distinct arrangement of atoms, making it a subject of study for chemists who enjoy unraveling complex molecular designs.
  • Potential Biological Activity: Compounds with similar structural motifs have been investigated for therapeutic properties. It’s crucial to explore whether this specific compound displays any biological activity, potentially serving as a lead compound for drug development.
  • Applications in Material Science: The unique arrangement of atoms and functional groups might allow for interesting interactions with other materials, leading to potential applications in nanotechnology or the creation of novel materials.
  • Challenging Synthesis: The synthesis of such complex molecules presents significant challenges. Understanding the synthetic pathways can enhance the training and skillset of both budding chemists and experienced researchers.
  • Chemical Behavior: Its multiple functional groups suggest it may exhibit versatile reactivity, which can be fascinating for exploring reaction mechanisms and the development of new synthetic methods.

As noted by numerous researchers, “The exploration of complex organic compounds not only enhances our understanding of chemistry but also holds the potential for groundbreaking discoveries.” The study of this compound emphasizes the importance of chemical diversity in advancing both scientific knowledge and practical applications.

In conclusion, 21-hydroxy-10-isopropyl-11,19-dimethyl-9,26-dioxa-3,15,28-triazatricyclo[23.2.1.03,7]octacosa-1(27),6,12,17,19,25(28)-hexaene-2,8,14,23-tetrone serves as an exemplary model for exploring the complex interactions and extensive possibilities of organic chemistry.

Synonyms
virginiamycin m1
Pristinamycin IIA;Ostreogrycin A
Pristinamycin IIA
21411-53-0
BCP31523
DB-045572
Q7245902
Ostreogrycin A;Virginiamycin M1;Streptogramin A;Mikamycin A
21-hydroxy-11,19-dimethyl-10-propan-2-yl-9,26-dioxa-3,15,28-triazatricyclo[23.2.1.03,7]octacosa-1(27),6,12,17,19,25(28)-hexaene-2,8,14,23-tetrone