Interesting facts
Interesting Facts About 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one
This compound, known as 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one, is a fascinating member of the class of compounds known as amino ketones. Its complex structure and unique properties make it an intriguing subject of study in both organic chemistry and pharmacology. Here are some noteworthy highlights:
- Pharmaceutical Potential: This compound exhibits interesting biological activities, making it a candidate for drug development. Researchers are particularly interested in its interactions with neurological receptors, contributing to potential therapeutic applications.
- Synthetic Pathways: The synthesis of this compound showcases various organic reactions, including nucleophilic substitutions and reductive amination. Understanding these pathways is essential for chemists looking to design similar compounds.
- Functional Groups: The presence of a chlorophenyl moiety and a tert-butylamino group significantly influences the compound's reactivity and solubility. This makes it an essential topic in studies emphasizing structure-activity relationships (SAR).
- Structure-Activity Relationships: Investigating how modifications to either the phenyl or the tert-butyl groups affect biological activity can provide valuable insights into receptor binding and pharmacodynamics.
- Environmental Impact: As with many organic compounds, the environmental stability and possible degradation pathways are important considerations, particularly for industrial applications.
In summary, 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one is a compelling compound with multifaceted implications in scientific research. The ongoing exploration of its properties and effects has the potential to unlock new discoveries in medicinal chemistry and beyond. As the scientific community advances, compounds like this one will continue to offer valuable avenues for innovation and study.
Synonyms
bupropion
Amfebutamone
34911-55-2
2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one
Amfebutamon
Wellbutrin
34841-39-9
amfebutamonum
Amfebutamona
Elontril
(+-)-Bupropion
Wellbatrin
Amfebutamonum [INN-Latin]
Zyban
Amfebutamona [INN-Spanish]
AMFEBUTAMONE HCl
Bupropion SR
bupropione
alpha-(tert-butylamino)-m-chloropropiophenone
UNII-01ZG3TPX31
Bupropion (INN)
BRN 2101062
01ZG3TPX31
CHEBI:3219
Bupropion slow release
(+-)-1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone
Bupropion extended release
CHEMBL894
NSC-758686
DTXSID7022706
HSDB 6988
(+-)-2-(tert-Butylamino)-3'-chlorpropiophenon
(+-)-2-(tert-Butylamino)-3'-chloropropiophenone
NSC 758686
BUPROPION [INN]
1-Propanone, 1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-
Bupropion [INN:BAN]
BUPROPION (MART.)
BUPROPION [MART.]
1-Propanone, 1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-, (+-)-
Amfebutamonum (INN-Latin)
Amfebutamona (INN-Spanish)
(+/-)-2-(tert-butylamino)-3'-chloropropiophenone
1-(3-Chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone
1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]propan-1-one
1-Propanone, 1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]-
1-PROPANONE, 1-(3-CHLOROPHENYL)-2-((1,1-DIMETHYLETHYL)AMINO)-(+/-)-
Bupropion (R)-Isomer
Bupropion (USAN)
bupropionum
Zyban (Salt/Mix)
Amfebutamonum (Latin)
1-propanone, 1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-,(+-)-
Budeprion (Salt/Mix)
Amfebutamone(Bupropion)
Spectrum_001663
Wellbutrin (Salt/Mix)
SpecPlus_000954
BUPROPION [MI]
(.+/-.)-Bupropion
2-(Tert-Butylamino)-3'-chloropropiophenone
Prestwick0_000249
Prestwick1_000249
Prestwick2_000249
Prestwick3_000249
Spectrum2_001659
Spectrum3_000644
Spectrum4_000614
Spectrum5_001406
BUPROPION [VANDF]
BUPROPION [WHO-DD]
Lopac0_000166
SCHEMBL38777
BSPBio_000038
BSPBio_002247
KBioGR_001168
KBioSS_002143
MLS001424015
DivK1c_007050
SPBio_001817
SPBio_002257
BPBio1_000042
DTXCID002706
GTPL7135
KBio1_001994
KBio2_002143
KBio2_004711
KBio2_007279
KBio3_001467
N06AX12
HMS2051G10
HMS2089G14
HMS2232P04
HMS3369P11
HMS3393G10
BCP24193
AC-197
BBL029065
BDBM50048392
STL373006
AKOS015961770
BUPROPION COMPONENT OF CONTRAVE
CCG-100858
CCG-204261
DB01156
NC00108
SDCCGSBI-0050154.P004
MRF-0000143
NCGC00015122-03
NCGC00015122-04
NCGC00015122-06
NCGC00015122-07
NCGC00015122-09
NCGC00015122-14
NCGC00015122-20
NCGC00089751-02
NCI60_002714
SMR000472526
SBI-0050154.P003
DB-048697
AB00053756
m-chloro-alpha-(tert-butylamino)propiophenone
NS00000397
.alpha.-(tert-Butylamino)-m-chloropropiophenone
C06860
D07591
Propiophenone, 2-(tert-butylamino)-3'-chloro-
AB00053756-16
AB00053756-18
AB00053756-19
AB00053756_20
AB00053756_21
EN300-1707781
2-tert-Butylamino-1-(3-chlorophenyl)propan-1-one
L000725
Q834280
(.+/-.)-2-(tert-Butylamino)-3'-chloropropiophenone
BRD-A05186015-003-05-7
BRD-A05186015-003-09-9
BRD-A05186015-003-19-8
BRD-A05186015-003-20-6
2-(tert-Butylamino)-1-(3-chlorophenyl)-1-propanone #
1-Propanone, 1-(3-chlorophenyl)-2-[(1, 1-dimethylethyl)amino]-
1-Propanone, 1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-, (.+/-.)-
Solubility of 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one
The solubility of 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one (C13H18ClNO) in various solvents presents a fascinating consideration due to its structural components. Here are some key points regarding its solubility:
As a rule of thumb, one can expect that compounds with such structural characteristics will exhibit solubility trends influenced by both their functional groups and steric hindrance characteristics. In summary, while this compound shows reasonable solubility in select polar and non-polar solvents, the specific context of use and conditions must be considered for optimal results.