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Thioglycolic acid

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Identification
Molecular formula
C2H4O2S
CAS number
68-11-1
IUPAC name
2-sulfanylacetic acid
State
State

At room temperature, thioglycolic acid is typically found as a liquid. It is known for its volatility and pungent odor.

Melting point (Celsius)
-16.50
Melting point (Kelvin)
256.65
Boiling point (Celsius)
96.00
Boiling point (Kelvin)
369.15
General information
Molecular weight
92.12g/mol
Molar mass
92.1190g/mol
Density
1.3250g/cm3
Appearence

Thioglycolic acid is a colorless liquid with a strong and unpleasant odor. It is usually found in its aqueous form and is highly corrosive. Due to its reactivity, it is often handled with care.

Comment on solubility

Solubility of 2-sulfanylacetic acid (C2H4O2S)

2-sulfanylacetic acid, commonly recognized for its thiol group, exhibits unique solubility properties that are important for various applications. Understanding the solubility of this compound is crucial, as it can influence reactivity, bioavailability, and its utilization in chemical synthesis. Here are some key points regarding the solubility of this compound:

  • Water Solubility: 2-sulfanylacetic acid is polar, primarily due to the presence of the carboxylic acid (-COOH) and thiol (-SH) functional groups. As a result, it is soluble in water, allowing it to engage in various aqueous reactions.
  • Organic Solvents: It generally shows moderate solubility in organic solvents, influenced by the solvent's polarity. Solvents like ethanol and methanol are particularly effective due to their ability to interact with the polar functionalities.
  • Impact of pH: The solubility dynamics can also depend on the pH of the solution. In acidic conditions, the carboxylic acid group remains protonated, while in basic conditions, it may ionize, potentially enhancing solubility.
  • Temperature Effects: Like many organic acids, solubility tends to increase with temperature, which may facilitate its use in various thermal reactions or processes.

In conclusion, 2-sulfanylacetic acid's solubility characteristics make it highly functional in both aqueous and organic environments, an essential factor for its applications in both laboratory and industrial settings. Knowing when and where it dissolves can unlock its full potential in chemical processes.

Interesting facts

Exploring 2-Sulfanylacetic Acid

2-Sulfanylacetic acid, often referred to as thioacetic acid, is an intriguing compound in the world of organic chemistry. As a carboxylic acid containing a thiol group, its unique structure opens doors to a range of fascinating applications and properties.

Key Features:

  • Functional Versatility: The compound includes both a carboxylic acid and a thiol functional group, making it a valuable precursor in the synthesis of various organic compounds.
  • Biological Relevance: It is studied for its potential biological activities and its role in the metabolism of certain sulfur-containing compounds in biological systems.
  • Synthetic Utility: 2-Sulfanylacetic acid can be utilized in the manufacture of pharmaceuticals, specializing in compounds with thioester linkages that are essential for biological functionality.

Due to its reactivity and the presence of sulfur, this compound is of particular interest in the field of medicinal chemistry. Researchers are investigating its potential as a bioactive molecule, appealing to those who are passionate about drug discovery and development.

Quote to Remember:

As a chemistry enthusiast said, “The beauty of chemistry lies in the small details that can lead to profound discoveries.” The case of 2-sulfanylacetic acid embodies this commitment to understanding and innovating within the realm of chemical compounds.

In summary, 2-sulfanylacetic acid is a compound that not only enriches the study of organic chemistry but also paves the way for countless applications in pharmaceuticals and beyond. Its rich chemical structure and potential for discovery make it a worthy subject for study.

Synonyms
mercaptoacetic acid
thioglycolic acid
68-11-1
Acetic acid, mercapto-
2-Mercaptoacetic acid
2-Thioglycolic acid
Sulfanylacetic acid
Thioglycollic acid
2-sulfanylacetic acid
Thiovanic acid
Mercaptoessigsaeure
Glycolic acid, thio-
Acide thioglycolique
Glycolic acid, 2-thio-
USAF CB-35
Acetic acid, 2-mercapto-
Kyselina thioglykolova
Thioglykolsaeure
Kyselina merkaptooctova
alpha-Mercaptoacetic acid
Merkaptoessigsaeure
mercapto acetic acid
mercapto-acetic acid
Mercaptoethanoic acid
NSC 1894
Acide thioglycolique [French]
Kyselina thioglykolova [Czech]
CCRIS 4873
Kyselina merkaptooctova [Czech]
HSDB 2702
NSC-1894
.alpha.-Mercaptoacetic acid
EINECS 200-677-4
UN1940
UNII-7857H94KHM
BRN 0506166
DTXSID8026141
CHEBI:30065
AI3-24151
7857H94KHM
MFCD00004876
Thioglycolic Acid (~90%)
THIOGLYCOLIC ACID [MI]
CHEMBL116455
DTXCID406141
EC 200-677-4
MERCAPTOACETIC ACID [HSDB]
THIOGLYCOLIC ACID [WHO-DD]
THIOGLYCOLLIC ACID [MART.]
4-03-00-00600 (Beilstein Handbook Reference)
thioglycolicacid
Acide thioglycolique (French)
Kyselina thioglykolova (Czech)
Kyselina merkaptooctova (Czech)
THIOGLYCOLLIC ACID (MART.)
CAS-68-11-1
mercaptoactic acid
2Thioglycolic acid
2-mercaptoaceticacid
2mercaptoacetic acid
Glycolic acid, thio
Acetic acid, mercapto
Sulfanylacetic acid #
Glycolic acid, 2thio
mercaptoacetic acid (thioglycolic acid)
HSCH2COOH
2-mercaptoethanoic acid
Ethanethiol-2-acid-1
THIOGYCOLLIC ACID
HSCH2CO2H
WLN: SH1VQ
SULFHYDRYLACETIC ACID
Thioglycolic acid (ACGIH)
Thioglycolic acid, >=97%
Thioglycolic acid, >=98%
Thioglycolic acid, >=99%
THIOGLYCOLIC ACID [INCI]
Thioglycolic acid, LR, ~80%
CWERGRDVMFNCDR-UHFFFAOYSA-
NSC1894
STR00166
Tox21_201717
Tox21_303306
ALPHA-ACETIC ACID, MERCAPTO-
BDBM50336509
MSK000892
STL264219
AKOS000118940
DB15429
FT47141
Thioglycolic acid, for synthesis, 97%
UN 1940
NCGC00249103-01
NCGC00257153-01
NCGC00259266-01
NCI60_001579
1ST000892
DB-002789
Thioglycolic acid [UN1940] [Corrosive]
M0052
NS00003173
EN300-19250
C02086
E78850
Q414738
InChI=1/C2H4O2S/c3-2(4)1-5/h5H,1H2,(H,3,4)
200-677-4