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Phenelzine hydrochloride

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Identification
Molecular formula
C8H12N2·HCl
CAS number
51-71-8
IUPAC name
2-phenylpropylhydrazine;hydrochloride
State
State

At room temperature, Phenelzine hydrochloride is typically found in a solid state as a powder. It is stable under normal conditions used in laboratories and pharmaceutical preparations.

Melting point (Celsius)
133.00
Melting point (Kelvin)
406.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
172.23g/mol
Molar mass
172.2330g/mol
Density
1.0710g/cm3
Appearence

Phenelzine hydrochloride typically appears as a white or off-white crystalline powder. It is usually odorless and can be quite hygroscopic, absorbing moisture from the air, hence it should be stored in a well-sealed container to maintain its stability.

Comment on solubility

Solubility of 2-phenylpropylhydrazine Hydrochloride

The solubility of 2-phenylpropylhydrazine hydrochloride (C8H12N2·HCl) is quite significant in certain solvents, making it an intriguing compound from a chemical standpoint. Its behavior in solution can be described as follows:

  • Water Solubility: 2-phenylpropylhydrazine hydrochloride is generally readily soluble in water, which is typical for many hydrochloride salts due to their ionic nature.
  • Solvent Compatibility: In addition to water, it also shows enhanced solubility in polar solvents such as methanol and ethanol.
  • pH Influence: The solubility can be affected by pH; it is often more soluble in acidic solutions compared to neutral or basic environments.
  • Temperature Effects: Increasing the temperature can further improve solubility, allowing for greater amounts to be dissolved.

It's important to note that factors such as ionic strength and the presence of other solutes can also impact the solubility profile of this compound. Overall, 2-phenylpropylhydrazine hydrochloride exhibits a favorable solubility in various conditions, making it a useful candidate for applications in chemical synthesis and research.

Interesting facts

Interesting Facts about 2-Phenylpropylhydrazine Hydrochloride

2-Phenylpropylhydrazine hydrochloride is a fascinating compound, particularly in the realms of medicinal chemistry and pharmacology. Below are some engaging insights about this intriguing substance:

  • Historical Significance: This compound is known for its role in the development of certain anti-cancer drugs. Its hydrazine moiety is a key feature in several biologically active compounds.
  • Biological Activity: As a hydrazine derivative, 2-phenylpropylhydrazine has been explored for its potential as a monoamine oxidase inhibitor (MAOI). This property has implications in treating mood disorders.
  • Research Applications: Scientists often utilize this compound in biochemical assays to study the mechanisms of neurotransmitter metabolism and its effects on the central nervous system.
  • Synthesis: The synthesis of this compound is of particular interest in organic chemistry, involving the reaction of hydrazine derivatives with appropriate ketones or aldehydes, showcasing key concepts in organic reaction mechanisms.
  • Safety Considerations: As with many hydrazines, safety precautions are essential when handling 2-phenylpropylhydrazine hydrochloride, given its potential reactivity and health concerns associated with long-term exposure.

In conclusion, 2-phenylpropylhydrazine hydrochloride is more than just a chemical entity; it embodies a rich intersection of history, biology, and chemistry. Its implications in therapeutic applications make it a compound of great interest for both research and practical uses in medicinal chemistry.

Synonyms
Catroniazid
Catroniacid
Pheniprazine HCl
Fenizin hydrochloride
Phenizine hydrochloride
Cavodil
CCRIS 1417
Catral
Chlorowodorek feniprazyne
5B3OM8452C
Chlorowodorek feniprazyne [Polish]
Phenylisopropylhydrazine hydrochloride
JB 516
NSC 17766
UNII-5B3OM8452C
Hydrazine, (2-phenylpropyl)-, hydrochloride (1:1)
(1-Methyl-2-phenylethyl)hydrazineium chloride
(1-Methyl-2-phenylethyl)-hydrazinium chloride
2-phenylpropylhydrazine;hydrochloride
1743-28-8
(1-Methyl-2-phenylethyl)hydrazine monohydrochloride
Hydrazine, (1-methyl-2-phenylethyl)-, monohydrochloride
HYDRAZINE, (alpha-METHYLPHENETHYL)-, MONOHYDROCHLORIDE
JB-516
PHENIPRAZINE DL-FORM HYDROCHLORIDE [MI]
SCHEMBL11531581
PHENIPRAZINE DL-FORM HYDROCHLORIDE
Q27261771
Hydrazine, (1-methyl-2-phenylethyl)-, monohydrochloride (9CI)