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2-Phenylisothiazolo[5,4-b]pyridin-3-one

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Identification
Molecular formula
C12H8N2OS
CAS number
29140-48-5
IUPAC name
2-phenylisothiazolo[5,4-b]pyridin-3-one
State
State

At room temperature, 2-Phenylisothiazolo[5,4-b]pyridin-3-one is a solid. It is stable under normal conditions and does not readily sublime or decompose. The compound is typically kept in a dry and cool place to maintain its stability.

Melting point (Celsius)
231.00
Melting point (Kelvin)
504.15
Boiling point (Celsius)
508.00
Boiling point (Kelvin)
781.15
General information
Molecular weight
240.28g/mol
Molar mass
240.2750g/mol
Density
1.3200g/cm3
Appearence

2-Phenylisothiazolo[5,4-b]pyridin-3-one commonly appears as a solid crystalline substance. The crystals are usually pale yellow or off-white in color, which can vary slightly depending on the specific batch or any impurities present.

Comment on solubility

Solubility of 2-phenylisothiazolo[5,4-b]pyridin-3-one

The solubility of 2-phenylisothiazolo[5,4-b]pyridin-3-one (C12H8N2OS) can be intriguing to analyze due to its unique chemical structure. Generally, the solubility of a compound in a particular solvent is influenced by various factors, including:

  • Polarity: The presence of polar functional groups can enhance solubility in polar solvents.
  • Hydrogen bonding: Compounds capable of forming hydrogen bonds tend to dissolve better in solvents that can also participate in hydrogen bonding.
  • Molecular weight: Higher molecular weights may correlate with lower solubility, although exceptions exist.
  • Temperature: Solubility often increases with temperature, which can significantly impact solute-solvent interactions.

In the case of 2-phenylisothiazolo[5,4-b]pyridin-3-one, its hybrid structure comprising both aromatic and heterocyclic components suggests moderate solubility characteristics. You may encounter the following behaviors:

  • Poor solubility in water due to its hydrophobic aromatic groups.
  • Better solubility in organic solvents such as dichloromethane or dimethyl sulfoxide (DMSO).
  • Potentially affected solubility with pH changes, suggesting interactions with protic solvents.

Ultimately, understanding the solubility of 2-phenylisothiazolo[5,4-b]pyridin-3-one is vital for its applications in various chemical processes and formulations. As with many compounds, measuring specific solubility parameters in relevant solvents can yield valuable insights into its behavior in real-world applications.

Interesting facts

Interesting Facts about 2-phenylisothiazolo[5,4-b]pyridin-3-one

2-phenylisothiazolo[5,4-b]pyridin-3-one is a fascinating compound that exhibits unique chemical properties and potential applications. Here are some key insights:

  • Structural Composition: This compound consists of a pyridine ring fused with an isothiazole moiety, which contributes to its distinctive chemical behavior. The presence of the phenyl group enhances its stability and versatility in chemical reactions.
  • Biological Activity: 2-phenylisothiazolo[5,4-b]pyridin-3-one has garnered interest for its potential biological activities, including antimicrobial and anti-inflammatory properties. Researchers are exploring its possibilities in medicinal chemistry, targeting various health issues.
  • Applications in Organic Synthesis: This compound serves as an important building block in organic synthesis, often used to create more complex chemical structures. Its unique functional groups facilitate diverse chemical reactions, making it a valuable tool for chemists.
  • Research and Development: Scientists are actively investigating its applications in pharmaceuticals, material science, and agrochemicals. The ongoing research aims to uncover new uses and enhance its efficacy.
  • Potential for Innovation: As a compound with innovative structures, 2-phenylisothiazolo[5,4-b]pyridin-3-one may lead to the design of new therapeutic agents or advanced materials. The prospects for novel discoveries in the field of chemistry are endless.

In conclusion, 2-phenylisothiazolo[5,4-b]pyridin-3-one is not just a compound with a complex name; it represents a convergence of chemistry and potential application in various fields. As researchers continue to explore its properties, it might very well play a role in shaping future advancements in multiple scientific arenas.

Synonyms
xg076
TCMDC-125874
104857-27-4
2-Phenyl-isothiazolo[5,4-b]pyridin-3-one
CHEMBL316658
DTXSID10274477
Isothiazolo[5,4-b]pyridin-3(2H)-one, 2-phenyl-
2-phenylisothiazolo[5,4-b]pyridin-3(2H)-one
cid_5703
SCHEMBL26964521
DTXCID80225956
KUC103883N
BDBM50037078
KSC-6-109
2-(Phenyl)-isothiazolo[5,4-b]pyridin-3(2H)-one