Skip to main content

Phenelzine

ADVERTISEMENT
Identification
Molecular formula
C8H12N2
CAS number
51-71-8
IUPAC name
2-phenylethylhydrazine
State
State

At room temperature, phenelzine is a solid. It is usually handled and stored in the form of a dry powder or compressed into tablets for pharmaceutical use.

Melting point (Celsius)
94.00
Melting point (Kelvin)
367.15
Boiling point (Celsius)
214.00
Boiling point (Kelvin)
487.15
General information
Molecular weight
136.19g/mol
Molar mass
136.1910g/mol
Density
1.1240g/cm3
Appearence

Phenelzine typically appears as a white to off-white crystalline powder. It may also come in tablet form for pharmaceutical applications. The powder is stable when kept dry and at room temperature, but it should be protected from light and moisture to maintain its stability and efficacy.

Comment on solubility

Solubility of 2-Phenylethylhydrazine

2-Phenylethylhydrazine (C8H12N2) exhibits unique solubility characteristics that are important for its applications in various fields. Understanding its solubility can provide valuable insight into its behavior in different environments and formulations.

Key Points on Solubility:

  • Polar vs. Non-Polar Solubility: 2-Phenylethylhydrazine is largely non-polar due to its hydrophobic aromatic ring. This characteristic leads to it being more soluble in non-polar solvents such as hexane and toluene.
  • Limited Solubility in Water: The molecule's hydrophobic properties limit its solubility in water, making it relatively insoluble in aqueous environments. This is typical for compounds with significant aromatic character.
  • Solvent Interactions: When interacting with solvents, 2-phenylethylhydrazine may form hydrogen bonds, albeit weakly, depending on the nature of the solvent. This can influence its overall solubility and reactivity.
  • Temperature Dependence: Like many organic compounds, solubility can be temperature-dependent. An increase in temperature often leads to enhanced solubility in organic solvents.

In summary, the solubility of 2-phenylethylhydrazine is dictated by its chemical structure, which primarily influences its interactions with various solvents. While it demonstrates affinity for non-polar environments, it is limited by its hydrophobic nature when attempting to solubilize in polar solvents like water.

Interesting facts

Interesting Facts About 2-Phenylethylhydrazine

2-Phenylethylhydrazine is a fascinating organic compound that has captured the interest of chemists and researchers alike. Here are some noteworthy points that highlight its unique characteristics and applications:

  • Chemical Structure: This compound features a hydrazine functional group, which is notable for its reactivity. The incorporation of the phenyl group significantly influences its chemical behavior, making it a key subject in studies related to hydrazine derivatives.
  • Pharmaceutical Relevance: 2-Phenylethylhydrazine has applications in the pharmaceutical industry, particularly in the synthesis of various biologically active compounds. Its derivatives have shown potential in treating conditions such as depression and anxiety.
  • Research Implications: The compound has been investigated in research focusing on neurobiology. Studies suggest its potential in enhancing dopaminergic activity, making it an interesting candidate for further exploration in addiction therapy.
  • Historical Context: This compound plays a role in the history of chemical research. Its derivatives have been employed in numerous experiments that have contributed to the broader understanding of hydrazine and its role in organic chemistry.
  • Potential Risks: While 2-phenylethylhydrazine has beneficial properties, it’s important to note the potential toxicity associated with hydrazine compounds. Researchers must handle it with care due to its reactive nature and potential health risks.

In summary, 2-phenylethylhydrazine is not just a simple organic compound; it embodies a rich interplay of chemistry and biology. Its diverse applications and implications make it a compound worth studying. As one chemist aptly stated, "Understanding simple compounds can lead to breakthroughs in complex systems." This reinforces the idea that the world of chemistry is interconnected, with each compound offering new insights and possibilities.

Synonyms
Phenelzine
51-71-8
2-Phenylethylhydrazine
Phenethylhydrazine
Nardil
Hydrazine, (2-phenylethyl)-
Fenelzyne
Fenelzyna
beta-Phenylethylhydrazine
Phenelzinum
Fenelzin
Fenelzina
2-Phenethylhydrazine
1-Hydrazino-2-phenylethane
Phenethyl-hydrazine
Phenalzine
(2-phenylethyl)hydrazine
Fenelzina [INN-Spanish]
Phenelzinum [INN-Latin]
HYDRAZINE, PHENETHYL-
W 1544-A
phenethyl hydrazine
W1544
EINECS 200-117-9
UNII-O408N561GF
BRN 0742354
HSDB 8127
O408N561GF
CHEMBL1089
CHEBI:8060
DTXSID2041094
4-15-00-01269 (Beilstein Handbook Reference)
Fenelzyna [Polish]
Fenelzyne [Polish]
Fenelzina (INN-Spanish)
Phenelzinum (INN-Latin)
Phenelzine [INN:BAN]
Phenylethylhydrazine
Phenelzine (BAN)
2 Phenethylhydrazine
beta Phenylethylhydrazine
Nardil (Salt/Mix)
Phenelzinum (Latin)
Phenelzine Free Base
Spectrum_000851
PHENELZINE [MI]
PHENELZINE [INN]
Prestwick0_000170
Prestwick1_000170
Prestwick2_000170
Prestwick3_000170
Spectrum2_001009
Spectrum3_000677
Spectrum4_000475
Spectrum5_000990
Lopac-P-6777
1-(2-phenethyl)hydrazine
PHENELZINE [VANDF]
CBChromo1_000176
.beta.-Phenylethylhydrazine
1-(2-Phenylethyl)hydrazine
PHENELZINE [WHO-DD]
Lopac0_000971
SCHEMBL34335
BSPBio_000039
BSPBio_002373
KBioGR_000950
KBioGR_002265
KBioSS_001331
KBioSS_002266
DivK1c_000062
SPBio_001137
SPBio_001960
1-(2-Phenylethyl)hydrazine #
BPBio1_000043
GTPL7266
DTXCID0021094
KBio1_000062
KBio2_001331
KBio2_002265
KBio2_003899
KBio2_004833
KBio2_006467
KBio2_007401
KBio3_001593
KBio3_002745
cMAP_000003
NINDS_000062
HMS3259L04
HY-B1018
BDBM50105417
MFCD00047825
AKOS000131105
CCG-205051
CS-4532
DB00780
FP13942
NC00692
SDCCGSBI-0050944.P005
IDI1_000062
NCGC00015830-01
NCGC00015830-03
NCGC00015830-04
NCGC00015830-05
NCGC00015830-07
NCGC00015830-13
NCGC00162301-01
AS-77074
SBI-0050944.P004
DB-052010
AB00053520
NS00098766
EN300-58071
C07430
D08349
F74244
W-1544
AB00053520_12
Q1747559
BRD-K87024524-065-05-2
BRD-K87024524-065-17-7
BRD-K87024524-065-18-5
14847-47-3
200-117-9