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2-Phenylcyclopropylamine

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Identification
Molecular formula
C9H11N
CAS number
930-68-7
IUPAC name
2-phenylcyclopropanamine
State
State

At room temperature, 2-Phenylcyclopropylamine is in a liquid state. Being a small amine, it is volatile, allowing it to easily transition between liquid and gaseous states under standard atmospheric pressure.

Melting point (Celsius)
15.00
Melting point (Kelvin)
288.15
Boiling point (Celsius)
141.00
Boiling point (Kelvin)
414.15
General information
Molecular weight
133.20g/mol
Molar mass
133.1960g/mol
Density
1.0188g/cm3
Appearence

2-Phenylcyclopropylamine is a colorless liquid. It may also appear as a colorless to pale yellow liquid depending on the purity and the conditions in which it is stored. Due to its structure, it may release an amine-like odor.

Comment on solubility

Solubility of 2-phenylcyclopropanamine (C9H11N)

2-phenylcyclopropanamine, with the molecular formula C9H11N, demonstrates unique solubility characteristics primarily influenced by its chemical structure. Being an amine, it may exhibit polar characteristics that can enhance its solubility in certain solvents.

Key Points About Solubility:

  • Solvent Interaction: This compound is likely to be soluble in polar solvents such as water or alcohols to a certain extent due to the presence of the amine group that can engage in hydrogen bonding.
  • Limited Solubility: However, the large phenyl ring can impede complete solubility in water, suggesting that it won't dissolve as easily as smaller or less bulky amines.
  • Hydrophobic Effects: The cyclopropane and phenyl portions contribute hydrophobic character, which may also limit solubility in purely polar solvents.

In summary, while 2-phenylcyclopropanamine may show some degree of solubility in polar solvents, its overall solubility will be moderate due to competing hydrophobic interactions from its aromatic structure.

Interesting facts

Interesting Facts about 2-Phenylcyclopropanamine

2-Phenylcyclopropanamine is an intriguing compound in the field of organic chemistry, and it has sparked significant interest due to its unique structure and potential applications. Here are some interesting points to consider:

  • Structural Significance: The cyclopropane ring is a three-membered carbon ring, which brings unique strain and reactivity. This strain can lead to interesting chemical properties when compared to similar structures without the ring.
  • Biological Importance: Compounds containing amine functional groups, such as 2-phenylcyclopropanamine, are often studied for their pharmacological properties. They have been investigated for potential uses as antidepressants and stimulants.
  • Derivative Potential: The presence of both a phenyl group and a cyclopropane moiety allows for numerous derivatives to be synthesized. This opens avenues for exploration in medicinal chemistry, where slight modifications to the structure can lead to vastly different biological activities.
  • Studied in Synthesis: The compound has been used as a model in synthetic organic chemistry to develop new methodologies for compound synthesis, particularly in the realm of amine chemistry.

As noted by researchers, "The unique elements of 2-phenylcyclopropanamine enable scientists to explore and understand complex interactions in organic synthesis and biological systems."
This makes it a versatile compound for those engaged in chemistry.

In conclusion, 2-phenylcyclopropanamine not only serves as an excellent example of structural diversity in chemical compounds but also represents a potential lead structure for further research and applications in various scientific fields. Its unique properties continue to inspire advancements in both academic and applied chemistry.

Synonyms
2-phenylcyclopropan-1-amine
tranylcypromine
54-97-7
2-Phenylcyclopropanamine
dl-Tranylcypromine
2-phenylcyclopropylamine
Parnate
2-Phenylcyclopropane-1-amine
Transamine
trans-2-Phenylcyclopropylamine
Racemic Tranylcypromine
Jatrosom
CHEMBL313833
Cyclopropylamine, trans-2-phenyl-
Cyclopropanamine, 2-phenyl-, trans-
2-Phenyl-cyclopropylamine
Cyclopropanamine, 2-phenyl-
(1s,2r)-2-phenylcyclopropylamine
(1S,2R)-2-Phenyl-cyclopropylamine
Parnate (Salt/Mix)
(rel)-Tranylcypromine
SKF-trans-385
(.+/-.)-Tranylcypromine
NSC80664
(1R,2S)-2-phenyl-cyclopropylamine
MFCD00865363
MFCD01735853
NSC-80664
(+/-)-trans-2-phenylcyclopropylamine
(.+/-.)-trans-2-Phenylcyclopropamine
(.+/-.)-trans-2-Phenylcyclopropylamine
(1R*,2S*)-2-phenylcyclopropan-1-amine
MFCD04114536
Tranylcypromine,(+)
Tranylcypromine,(-)
Spectrum_001598
(+/-)-Tranylcypromine
Spectrum3_001068
Spectrum4_001219
Spectrum5_001829
2-PCPA
2- Amino-cyclopropylbenzene
Lopac0_001013
SCHEMBL40651
KBioGR_001658
KBioSS_002078
GTPL5281
KBio2_002078
KBio2_004646
KBio2_007214
KBio3_001876
DTXSID30859306
CHEBI:131512
US8609708, 6 Tranylcypromine
Cyclopropanamine, trans-(.+-.)-
Cyclopropylamine, trans-(.+-.)-
EAA54834
BDBM50113851
CCG-40399
US8609708, 6 Tranyl- cypromine
AKOS005217104
2-Phenyl-Cyclopropylamine Hydrochloride
DB00752
SB33883
SB36881
SB36882
SB40902
SDCCGSBI-0050986.P002
Cyclopropanamine,2-phenyl-, (1S,2R)-
NCGC00015848-02
NCGC00015848-03
NCGC00015848-04
NCGC00162316-01
BS-13286
SY037504
SY268491
DB-338679
CS-0091206
EN300-54719
AB01007711-01
Q420885
CYCLOPROPANAMINE,2-PHENYL-, (1R,2S)-REL-
F2173-0870