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Pyruvic acid

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Identification
Molecular formula
C3H4O3
CAS number
127-17-3
IUPAC name
2-oxopropanoic acid
State
State

Pyruvic acid is a liquid at room temperature, although it can also form crystals in its solid form.

Melting point (Celsius)
11.80
Melting point (Kelvin)
284.95
Boiling point (Celsius)
165.00
Boiling point (Kelvin)
438.15
General information
Molecular weight
88.06g/mol
Molar mass
88.0620g/mol
Density
1.2500g/cm3
Appearence

Clear, colorless liquid with a pungent smell. In its pure form, it is a liquid but can also form white crystals when in solid form.

Comment on solubility

Solubility of 2-oxopropanoic acid (C3H4O3)

2-oxopropanoic acid, also known as pyruvic acid, is notable for its solubility characteristics. This compound exhibits a good degree of solubility in various solvents, particularly in water, which is a key factor for many biochemical processes.

  • Solubility in Water: 2-oxopropanoic acid is highly soluble in water due to the following reasons:
    • The presence of a carboxyl group (-COOH) that can form hydrogen bonds with water molecules.
    • The polar nature of the compound helps facilitate dissolution in aqueous environments, making it readily absorbable in physiological conditions.
  • Solubility in Other Solvents: While primarily soluble in water, 2-oxopropanoic acid also shows solubility in:
    • Organic solvents like ethanol and acetone, which are commonly used in laboratory settings.
    • Moderate solubility in certain nonpolar solvents, but much less than in polar ones.

In conclusion, the solubility of 2-oxopropanoic acid in both water and various organic solvents underscores its significance in biological processes and synthetic applications. As highlighted, its solubility can be attributed to the effective interplay of its functional groups and the polarity of the molecule.

Interesting facts

Interesting Facts about 2-Oxopropanoic Acid

2-Oxopropanoic acid, also known as pyruvic acid, is a fascinating component in the realm of biochemistry, playing a pivotal role in various metabolic pathways. Here are some key points to consider:

  • Metabolic Significance: Pyruvic acid is primarily known for its role in the cellular respiration process. It serves as a crucial intermediate in the conversion of glucose to energy, specifically during glycolysis.
  • Precursor to Other Compounds: It is not just a passive player; 2-oxopropanoic acid acts as a precursor to several important biomolecules, including amino acids and fatty acids, making it vital for both energy production and biosynthesis.
  • Acid-Base Characteristics: The compound possesses both acidic and keto groups, allowing it to participate in various chemical reactions, including esterification and reduction, which are essential in organic chemistry.
  • Clinical Relevance: In clinical biochemistry, elevated levels of pyruvic acid can indicate certain metabolic disorders, making it an important marker in diagnostics.
  • Industrial Uses: Beyond its biological significance, 2-oxopropanoic acid finds applications in the food and pharmaceutical industries. It can be used as a food preservative and in the synthesis of various pharmaceuticals.

As an intriguing compound, 2-oxopropanoic acid exemplifies the intersection of biochemistry and organic chemistry, showcasing the complexity of life at a molecular level. Understanding its properties not only enriches our knowledge of metabolic processes but also informs various practical applications in diverse fields.

Synonyms
Pyruvic acid
2-Oxopropanoic acid
127-17-3
acetylformic acid
Pyroracemic acid
2-Oxopropionic acid
alpha-ketopropionic acid
Propanoic acid, 2-oxo-
2-Ketopropionic acid
2-Oxopropansaeure
2-Oxopropanoate
2-Oxopropionsaeure
alpha-Oxopropionsaeure
2-oxo-propionic acid
acide pyruvique
Pyruvic acid (natural)
a-Ketopropionic acid
CH3COCOOH
Brenztraubensaeure
FEMA No. 2970
alpha-keto propionic acid
NSC 179
AI3-11220
.alpha.-Ketopropionic acid
EINECS 204-824-3
UNII-8558G7RUTR
BRN 0506211
8558G7RUTR
DTXSID2021650
CHEBI:32816
Acid, Pyruvic
NSC-179
MFCD00002585
DTXCID801650
Propanoic acid, oxo-
4-03-00-01505 (Beilstein Handbook Reference)
2-oxo-Propanoic acid
CAS-127-17-3
Pyruvic acid (8CI)
Acetylformate
Pyroracemate
a-Ketopropionate
Brenztraubensaure
2-Oxopropionate
2-Oxopropansaure
2-oxopropionsaure
2-Oxopropanoicacid
alpha-Ketopropionate
alpha-Oxopropionsaure
nchembio867-comp8
2-oxo propanoic acid
Pyruvic acid, 95%
Pyruvic acid, 98%
4b5s
Pyruvic acid (Standard)
13C Labeled pyruvic acid
bmse000112
PYRUVIC ACID [MI]
Pyruvic acid-(1)(3)C
NCIOpen2_000039
PYRUVIC ACID [FHFI]
Pyruvic acid, p.a., 98%
PYRUVIC ACID [WHO-DD]
Pyruvic acid, >=97%, FG
GTPL4809
NSC179
CHEMBL1162144
BDBM19473
HY-Y0781R
Pyruvic acid, natural, >=80%
Propanoic acid, 2-oxo- (9CI)
HY-Y0781
ZDA12430
Tox21_202096
Tox21_303284
BBL027390
LMFA01060077
s3143
2-Oxopropanoic acid, Pyroracemic acid
AKOS000118803
CS-W020190
DB00119
FP47120
NCGC00165990-01
NCGC00165990-02
NCGC00257000-01
NCGC00259645-01
Pyruvic acid, technical, >=95.0% (T)
DB-221803
NS00013170
P0579
EN300-21306
C00022
Q213580
BRD-K86587225-236-02-5
B3CFF0AD-2F35-484C-B062-4AC88A1B2830
F2191-0254
Z104495240
a-Ketopropionic acid;2-Oxopropionic acid;Acetylformic acid
InChI=1/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6
Pyruvic acid, United States Pharmacopeia (USP) Reference Standard
204-824-3