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Methylglyoxal

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Identification
Molecular formula
C3H4O2
CAS number
78-98-8
IUPAC name
2-oxopropanal
State
State

At room temperature, methylglyoxal exists as a liquid. It is known for being miscible with water, meaning it can mix with water in any proportion without separating.

Melting point (Celsius)
-16.00
Melting point (Kelvin)
257.15
Boiling point (Celsius)
72.00
Boiling point (Kelvin)
345.15
General information
Molecular weight
72.06g/mol
Molar mass
72.0640g/mol
Density
1.0594g/cm3
Appearence

Methylglyoxal is a colorless liquid. It is hygroscopic, which means it readily absorbs moisture from the air. Upon exposure to air, it may take on a yellowish hue due to the formation of polymers or other degradation products. Its appearance can also include a pungent odor.

Comment on solubility

Solubility of 2-Oxopropanal

2-Oxopropanal, also known by its IUPAC name propionaldehyde, is a versatile compound with unique solubility properties. It has a chemical formula of C3H4O2 and is a small, polar molecule which enhances its solubility in various solvents.

Key Solubility Characteristics:

  • Water Solubility: 2-Oxopropanal is highly soluble in water due to its polar carbonyl functional group, facilitating hydrogen bonding with water molecules.
  • Organic Solvents: This compound is also soluble in many organic solvents such as ethanol and ether, owing to its relatively low molecular weight and hydrophilic properties.
  • pH Sensitivity: The solubility can be influenced by the pH of the solution, which may affect the ionization of the carbonyl group, thus impacting its overall solubility profile.

In conclusion, the solubility of 2-Oxopropanal makes it an important compound for various applications, especially in the chemical and pharmaceutical industries, where it can easily be incorporated in aqueous or organic environments for synthesis and reactions.

Interesting facts

Interesting Facts about 2-Oxopropanal

2-Oxopropanal, also known as acetylacetaldehyde, is a fascinating compound with several unique features that make it an interesting subject of study in organic chemistry.

Key Properties and Uses

  • Role in Metabolism: 2-Oxopropanal is an intermediate in several biochemical pathways, particularly in the metabolism of carbohydrates and lipids.
  • Precursor to Other Compounds: This compound can serve as a starting material for the synthesis of various biologically active molecules, including pharmaceuticals and agrochemicals.
  • Flavoring Agent: Its slightly sweet aroma has led to its use in the food industry as a flavoring agent, enhancing the sensory profile of various food products.
  • Research Interest: 2-Oxopropanal has garnered attention in scientific studies due to its potential role in studies related to environmental chemistry and industrial applications.

Chemical Behavior

As a carbonyl compound, 2-oxopropanal exhibits interesting reactivity, particularly in:

  • Nucleophilic Reactions: The carbonyl group makes it a prime target for nucleophiles, allowing it to participate in a variety of chemical reactions.
  • Condensation Reactions: It can undergo condensation to form more complex molecules, which is a valuable route in synthetic organic chemistry.

Future Directions in Research

Researchers are exploring novel applications of 2-oxopropanal in fields such as:

  • Green Chemistry: Its sustainable synthesis and utility in eco-friendly processes are under investigation.
  • Medicinal Chemistry: The potential for developing new medications by modifying 2-oxopropanal's structure is a rapidly evolving area of research.

In summary, 2-oxopropanal is not just a simple compound; its biochemical roles and versatility in synthetic chemistry render it an intriguing subject that continues to engage the curiosity of scientists and students alike.

Synonyms
methylglyoxal
pyruvaldehyde
2-Oxopropanal
pyruvic aldehyde
78-98-8
acetylformaldehyde
Acetylformyl
Propanal, 2-oxo-
2-Ketopropionaldehyde
METHYL GLYOXAL
Propanedione
Propanolone
2-Oxopropionaldehyde
Pyroracemic aldehyde
alpha-Ketopropionaldehyde
1-Ketopropionaldehyde
Glyoxal, methyl
Propionaldehyde, 2-keto
Propionaldehyde, 2-oxo-
1,2-Propanedione
Acetalformaldehyde
FEMA No. 2969
2-oxo-Propionaldehyde
CH3COCHO
acetyl formaldehyde
.alpha.-Ketopropionaldehyde
alpha-Ketopropionic aldehyde
NSC 79019
pyruvicaldehyde
CCRIS 1741
methyl-glyoxal
NSC 626580
CHEBI:17158
2-oxo-propanal
MFCD00006960
NSC-79019
METHYLGLYOXAL [MI]
722KLD7415
NSC-626580
METHYLGLYOXAL [IARC]
PYRUVALDEHYDE [FHFI]
METHYLGLYOXAL [WHO-DD]
2-oxopropanal, 40% in water
DTXSID0021628
NSC626580
NSC-337790
Pyruvoyl Group
METHYLGLYOXAL (IARC)
oxopropanal
Pyruvaldehyde (35% w/w aqueous)
Aldehyde, Pyruvic
51252-84-7
EINECS 201-164-8
NSC 337790
BRN 0906750
2Oxopropanal
Ethanol Ketone
UNII-722KLD7415
HSDB 7510
Propanal, 2oxo
Ketopropionaldehyde
2Oxopropionaldehyde
1Ketopropionaldehyde
2Ketopropionaldehyde
Propionaldehyde, 2oxo
Pyruvaldehyde (8CI)
alphaKetopropionaldehyde
2-keto Propionaldehyde
Propionaldehyde, 2keto
alphaKetopropionic aldehyde
Epitope ID:143620
WLN: VHV1
EC 201-164-8
4-01-00-03631 (Beilstein Handbook Reference)
Propanal, 2-oxo- (9CI)
Pyruvic aldehyde Methylglyoxal
METHYL GLYOXAL [HSDB]
Pyruvaldehyde, 40% in water
CHEMBL170721
DTXCID101628
GTPL6303
NSC79019
STR03080
Tox21_303931
NSC133492
NSC133493
Pyruvaldehyde, 35% aqueous solution
Pyruvaldehyde, 40% aqueous solution
AKOS000119318
AB00820
DB03587
FP33211
HY-W020014
NSC-133492
NSC-133493
CAS-78-98-8
Pyruvaldehyde (35per cent w/w aqueous)
NCGC00356972-01
BP-20618
CS-0031856
NS00005494
EN300-21293
C00546
Q903881
194597AC-5BFC-42EA-B6C8-DA2E5FAA13AF
F0001-2060
Z104495190
Pyruvic aldehyde - Technical grade, 35-45% w/w aqueous solution
201-164-8