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Pyruvic acid

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Identification
Molecular formula
C3H4O3
CAS number
127-17-3
IUPAC name
2-oxobutanoic acid
State
State

At room temperature, pyruvic acid is typically a liquid.

Melting point (Celsius)
11.80
Melting point (Kelvin)
284.95
Boiling point (Celsius)
165.00
Boiling point (Kelvin)
438.15
General information
Molecular weight
88.06g/mol
Molar mass
88.0610g/mol
Density
1.2500g/cm3
Appearence

Pyruvic acid is a colorless liquid with a sour, pungent odor. It is also hygroscopic, meaning it can absorb moisture from the air.

Comment on solubility

Solubility of 2-oxobutanoic acid (C3H4O3)

2-oxobutanoic acid, also known as ethyl pyruvate, exhibits interesting solubility characteristics that make it significant in various applications, particularly in the biochemical realm. Here's a closer look at its solubility profile:

  • Solvent Compatibility: 2-oxobutanoic acid is notably soluble in polar solvents such as water, which is largely due to its carboxylic acid functional group.
  • Hydrophilic Nature: The presence of the hydroxyl (-OH) and carbonyl (C=O) groups contributes to its strong intermolecular interactions with water, enhancing solubility.
  • Temperature Effects: Increasing temperature can further increase the solubility of 2-oxobutanoic acid in aqueous solutions, a behavior common among many organic acids.
  • pH Influence: The solubility can also be affected by the pH of the solution, as the acid dissociation can change depending on the surrounding environment, potentially increasing solubility in more alkaline conditions.

In summary, 2-oxobutanoic acid is highly soluble in water, showcasing its versatile nature in both chemical and biological systems. This property is pivotal for its functionality in various biochemical processes.

Interesting facts

Interesting Facts about 2-Oxobutanoic Acid

2-Oxobutanoic acid, also known as 4-oxobutanoic acid, is a fascinating compound in the realm of organic chemistry, with several intriguing aspects that highlight its significance:

  • Metabolic Intermediary: This compound is an essential intermediate in various metabolic pathways. It plays a crucial role in the synthesis of amino acids and the metabolism of carbohydrates.
  • Presence in Nature: 2-Oxobutanoic acid is not just a laboratory compound; it is naturally present in some biological systems, contributing to the complex chemical reactions that sustain life.
  • Research Applications: This acid has gained attention in medicinal chemistry due to its potential applications in drug design and biochemistry. Studies suggest it may influence pathways related to energy metabolism.
  • Versatile Reactions: As a keto acid, it can readily participate in various chemical reactions, such as decarboxylation and transamination, making it a valuable compound for synthetic organic chemistry.
  • Chemical Derivatives: 2-Oxobutanoic acid can serve as a precursor for numerous derivatives, which can be synthesized to study various biological processes or to create new therapeutic agents.

In summary, 2-oxobutanoic acid is much more than a simple organic compound; it is a vital part of biochemistry and holds potential for future innovations in medicine and chemical synthesis. Researchers continue to explore its capabilities, heralding exciting possibilities for the scientific community.

Synonyms
2-oxobutanoic acid
2-ketobutyric acid
600-18-0
2-oxobutyric acid
alpha-ketobutyric acid
BUTANOIC ACID, 2-OXO-
3-Methylpyruvic acid
Ketobutyrate
Propionylformic acid
2-oxobutyrate
2-Ketobutanoic acid
Butyric acid, 2-oxo-
Pyruvic acid, methyl-
Formic acid, propionyl-
alpha-Oxo-n-butyric acid
alpha-oxobutyric acid
2-Oxo-n-butyric acid
alpha-Ketobutric acid
3-methyl pyruvic acid
alpha-ketobutyrate
2-oxo-butyrate
.alpha.-Oxobutyric acid
FEMA No. 3723
.alpha.-Ketobutyric acid
a-Ketobutyric acid
alpha-Keto-n-butyric acid
2-oxo-Butyric acid
2-oxo-butanoic acid
.alpha.-Oxo-n-butyric acid
2-keto-butyrate
B92RB6HY1A
NSC 60533
.alpha.-Keto-n-butyric acid
alpha-Oxobutanoic acid
CHEBI:30831
.alpha.-Ketobutric acid
EINECS 209-986-9
MFCD00004164
NSC-60533
.ALPHA.-OXOBUTANOIC ACID
DTXSID9060524
Butyric acid, 2-oxo- (8CI)
Butanoic acid, 2-oxo- (9CI)
2-OXOBUTYRIC ACID [FHFI]
2-Ketobutanoate
2KT
UNII-B92RB6HY1A
oxobutyric acid
alphaOxobutyrate
a-Ketobutyrate
a-Oxobutyrate
propionyl-formate
2oxobutyric acid
3-Methylpyruvate
2-oxobutanoicacid
2oxobutanoic acid
2-Oxo-Butanoate
2Ketobutyric acid
a-Oxobutyric acid
a-Oxo-n-butyrate
a-keto-n-Butyrate
2-Oxo-n-butyrate
methyl pyruvic acid
3Methylpyruvic acid
methyl-Pyruvic acid
?-Ketobutyric Acid
.alpha.-Oxobutyrate
alphaOxonbutyric acid
Butyric acid, 2oxo
2-keto-butyric acid
propionyl-formic acid
alpha-Oxo-n-butyrate
Butanoic acid, 2oxo
Pyruvic acid, methyl
alpha-Keto-n-butyrate
a-Oxo-n-butyric acid
a-keto-n-Butyric acid
Formic acid, propionyl
2-Oxobutanoic acid #
4b5t
bmse000325
2-Ketobutyric acid, 97%
SCHEMBL24128
2-Oxobutanoic acid (Standard)
CHEMBL171246
DTXCID5042740
2-Oxobutyric acid, >=95%, FG
HY-W007926R
NSC60533
LMFA01060002
s6329
AKOS005207091
2-Oxobutyric acid, analytical standard
CS-W007926
DB04553
FK52480
HY-W007926
PB43133
AC-37023
DS-14641
PD006009
SY011034
2-Keto-N-butyric acid;Propionylformic acid
DB-000166
2-Oxobutyric acid, purum, >=97.0% (T)
NS00014701
O0364
C00109
O10846
Q209457
35DB7B81-3F44-4D6F-9E8B-C0F8B751D3AD
209-986-9