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Aminomethylene acetonitrile

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Identification
Molecular formula
C3H4N2
CAS number
15583-52-1
IUPAC name
2-(methyleneamino)acetonitrile
State
State

Aminomethylene acetonitrile is generally a liquid at room temperature.

Melting point (Celsius)
-29.00
Melting point (Kelvin)
244.15
Boiling point (Celsius)
81.00
Boiling point (Kelvin)
354.15
General information
Molecular weight
68.08g/mol
Molar mass
68.0840g/mol
Density
0.8987g/cm3
Appearence

Aminomethylene acetonitrile is typically observed as a clear, colorless to slightly yellow liquid. It can appear as either a homogenous liquid at room temperature or may form into crystalline structures under certain conditions. The characteristic odor is typically sharp and pungent.

Comment on solubility

Solubility of 2-(Methyleneamino)acetonitrile

2-(Methyleneamino)acetonitrile, with the chemical formula C3H6N2, exhibits interesting solubility characteristics that are influenced by its molecular structure.

This compound is generally considered to be:

  • Soluble in polar solvents: Its amine and nitrile functional groups allow significant interaction with polar solvents, making it readily soluble in water and alcohols.
  • Less soluble in non-polar solvents: Due to its polar nature, solubility in non-polar solvents like hexane is minimal.

Understanding the solubility of this compound is crucial for its use in various applications and reactions. As cited, “the solubility behavior of organic compounds is often dictated by their functional groups.” This highlights the importance of considering both the molecular interactions and the environmental conditions when determining how 2-(methyleneamino)acetonitrile interacts with different solvents.

In conclusion, the solubility of 2-(methyleneamino)acetonitrile can be summarized as:

  1. Highly soluble in water and other polar solvents.
  2. Poorly soluble in non-polar solvents.

Such behavior can be vital in fields such as pharmaceuticals, where solubility plays a critical role in drug formulation and delivery.

Interesting facts

Interesting Facts about 2-(Methyleneamino)acetonitrile

2-(Methyleneamino)acetonitrile is a fascinating compound that plays a significant role in various fields of chemistry, particularly in synthetic and pharmaceutical chemistry. Here are some intriguing aspects of this compound:

  • Diverse Applications: This compound is often utilized as an intermediate in the synthesis of important pharmaceuticals and agrochemicals.
  • Functional Group Context: The presence of both the methylene and nitrile functional groups allows for interesting reactivity, which can be exploited for further chemical transformations.
  • Potential for Biological Activity: There is considerable interest in compounds that contain methyleneamino moieties due to their potential biological activities, making them an area of research in medicinal chemistry.
  • Synthetic Pathways: Chemists can create 2-(methyleneamino)acetonitrile through a variety of synthetic pathways, which often involve the use of readily available starting materials, showcasing creativity and innovation in organic synthesis.

In the realm of chemical research, 2-(methyleneamino)acetonitrile serves as a critical building block. Its ability to serve as a precursor for more complex structures illustrates the intricate scaffolding of organic synthesis. As scientists delve deeper into its properties and potential applications, this compound exemplifies the vital interplay between functional groups and biological relevance in modern chemical endeavors.

As one researcher aptly put it, "Understanding the reactivity of compounds like 2-(methyleneamino)acetonitrile not only enhances our synthetic toolkit but also expands the horizons of what's possible in drug discovery."

Synonyms
109-82-0
Methyleneaminoacetonitrile
2-(methyleneamino)acetonitrile
MAAN
(methyleneamino)acetonitrile
Acetonitrile, (methyleneamino)-
2-(methylideneamino)acetonitrile
Methyleniminoacetonitrile
N-Methyleneglycinonitrile
GLYCINONITRILE, N-METHYLENE-
(Methylenamino)acetonitrile
USAF DO-5
alpha-Hydroformamine cyanide
Methylene aminoacetonitrile
N-Methylene glycinonitrile
Methyleneiminoacetonitrile
UNII-VUC4O8Q6RO
VUC4O8Q6RO
EINECS 203-709-5
NSC 128385
BRN 1848155
AI3-17751
NSC-3486
NSC-57883
NSC-128385
DTXSID0059378
N-METHYLENE-GLYCINONITRILE
2-(METHYLENEAMINO)ACETONITRILE [MI]
WLN: NC1NU1
(methylideneamino)acetonitrile
.alpha.-Hydroformamine cyanide
Methyleneglycinonitrile
MFCD00001889
Methylenaminoacetonitril
DTXCID9033131
NSC3486
Acetonitrile, 2-(methyleneamino)-
NSC57883
BBL027363
NSC128385
STL373466
AKOS009157437
M0212
NS00023529
EN300-42036
Q27292022
Z425450894