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Glycine

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Identification
Molecular formula
C2H5NO2
CAS number
56-40-6
IUPAC name
2-(methylamino)acetic acid
State
State

At room temperature, glycine is in a solid state.

Melting point (Celsius)
233.00
Melting point (Kelvin)
506.15
Boiling point (Celsius)
233.00
Boiling point (Kelvin)
506.15
General information
Molecular weight
75.07g/mol
Molar mass
75.0670g/mol
Density
1.5950g/cm3
Appearence

Glycine is a colorless crystalline solid. It is soluble in water and has a sweetish taste.

Comment on solubility

Solubility of 2-(Methylamino)acetic Acid (C2H5NO2)

2-(Methylamino)acetic acid, commonly known as sarcosine, exhibits noteworthy solubility characteristics that are essential for various applications in biochemical and pharmaceutical contexts.

Key Solubility Features:

  • Water Solubility: Sarcosine is highly soluble in water. This trait facilitates its use in biochemical studies and as a potential therapeutic agent, as it allows for ease of formulation and administration.
  • Polar Nature: The presence of both an amino group and a carboxylic acid group enhances the compound's polarity, further contributing to its solubility in polar solvents.
  • Temperature Dependency: Similar to many organic compounds, the solubility of sarcosine may increase with temperature, making hot water an effective solvent for dissolving this compound.
  • pH Influence: The solubility can also be affected by pH levels; at lower pH (acidic conditions), the amino group can become protonated, which might enhance solubility.

As a general statement regarding solubility, it can be asserted that compounds like 2-(methylamino)acetic acid possess the ability to dissolve effectively in aqueous environments due to their structure and functional groups. This characteristic makes them valuable in a variety of scientific and medical applications.

Interesting facts

Interesting Facts about 2-(Methylamino)acetic Acid

2-(Methylamino)acetic acid, often referred to as beta-methylaminoacetic acid or simply methylglycine, represents a unique compound that plays a significant role in various biological processes. Here are some fascinating points about this compound:

  • Biological Significance: This compound is classified as an amino acid, specifically a non-proteinogenic amino acid, which means it isn’t integrated into proteins but still performs critical biosynthetic roles.
  • Important Metabolite: Methylglycine is involved in the biochemical pathway of glycine and is part of the serine-glycine cycle, which is essential for the metabolism of proteins and nucleic acids.
  • Health Aspects: It has been related to methylation processes in the human body and may have implications in health conditions associated with impaired methylation, such as cardiovascular diseases and certain types of cancer.
  • Pharmaceutical Potential: Ongoing research suggests that methylglycine may exhibit neuroprotective properties, raising interest for potential therapeutic applications in neurology.
  • Sources: This compound is found naturally in various foods, especially in higher concentrations in animal products, making it an important aspect of nutritional science.

In the realm of organic chemistry, 2-(methylamino)acetic acid serves as a point of interest for scientists studying metabolic pathways, pharmaceuticals, and nutrition. As we continue to explore its roles, this compound may offer further insights into human health and disease mechanisms. In the words of one researcher, "Understanding compounds like methylglycine opens doors to unlocking the complexities of human biochemistry."

Synonyms
sarcosine
107-97-1
N-methylglycine
Sarcosinic acid
2-(methylamino)acetic acid
Methylglycine
Glycine, N-methyl-
N-Methylaminoacetic acid
Sarcosin
Methylaminoacetic acid
(Methylamino)acetic acid
(Methylamino)ethanoic acid
Sargosine hydrochloride
Acetic acid, (methylamino)-
N-Methyl glycine
N-methyl-Glycine
MFCD00004279
Methylamino-Acetic Acid
L-sarcosine
BRN 1699442
MeGly
AI3-15410
EINECS 203-538-6
N-Methyl-glycocoll
N-Methylaminoacetate
(methylamino)acetate
UNII-Z711V88R5F
(methylamino)-Acetate
(Methylamino)ethanoate
25951-24-0
SAR
CHEBI:15611
Methylaminoethanoic acid
CH3NHCH2COOH
Z711V88R5F
SARCOSINE [MI]
(methylamino)-Acetic acid
2-Methylaminoethanoic acid
SARCOSINE [WHO-DD]
CHEMBL304383
DTXSID1047025
sarcosinate
H-Sar-OH
N-Methylglycocoll
Cocoylsarcosine
sarcosine zwitterion
Magnesium Sarcosylate
(methylammonio)acetate
(methylazaniumyl)acetate
Cocobetaine
Cocoyl sarcosine
CHEBI:57433
SMR000857358
N-Cocoyl-N-methylglycine
arcosine
NMethylglycine
methyl-glycine
NMethylglycocoll
UNII-820Q60DZ0I
N Methylglycine
methylaminoacetate
NMethyl glycocoll
Glycine, Nmethyl
N-Cocoyl sarcosine
Sarcosine, BioXtra
EINECS 270-156-4
Sarcosine, 98%
Me-Gly-OH
MeNHCH2COOH
NSC 118114
NMethylaminoacetic acid
METHYL GLYCOCOLL
2Methylaminoethanoic acid
CH3NHCH2CO2H
SARCOSINE [INCI]
acetic acid, methylamino-
N-METHYL GLYCOCOLL
N-Cocoyl-N-methyl glycine
bmse000160
Acetic acid, (methylamino)
MLS001335909
MLS001335910
GTPL4713
DTXCID9027025
Sarcosine, >=99.0% (NT)
820Q60DZ0I
HMS2231J19
BCP34413
STR01554
AC7804
BBL009707
BDBM50017225
NSC118114
s4702
STL141072
AKOS000120139
CCG-266018
CS-W018511
DB12519
FS02744
NSC-118114
BP-12554
DA-57664
Sarcosine, crystallized, >=98.0% (T)
SY001630
HY-101037
M0332
NS00004104
EN300-20732
N-methylglycine;Methylglycine; Sarcosinic acid
C00213
Q414157
2-Methylaminoethanoic acid; N-Methylglycine; H-Sar-OH
BRD-K51263939-001-08-6
F0001-0147
Z104480276
484652ED-E55A-4308-8F42-0903E08DBAF4
N-Methylglycine;(Methylamino)acetic acid;Sarcosinic acid;N-Methylglycocoll
203-538-6