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Pseudoephedrine hydrochloride

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Identification
Molecular formula
C10H15NO·HCl
CAS number
464-00-6
IUPAC name
2-(methylamino)-1-phenyl-propan-1-ol;hydrochloride
State
State

At room temperature, pseudoephedrine hydrochloride is in a solid state, appearing typically as a white crystalline powder.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.15
Boiling point (Celsius)
200.00
Boiling point (Kelvin)
473.15
General information
Molecular weight
201.71g/mol
Molar mass
201.7080g/mol
Density
1.0567g/cm3
Appearence

Crystal Form: Pseudoephedrine hydrochloride typically appears as a white crystalline powder or colorless crystals. It is known for its characteristic bitter taste.

Solubility: It is soluble in water and practically insoluble in chloroform and ether. The appearance of its aqueous solutions is clear and usually colorless.

Comment on solubility

Solubility of 2-(methylamino)-1-phenyl-propan-1-ol;hydrochloride

The solubility of 2-(methylamino)-1-phenyl-propan-1-ol;hydrochloride is an important aspect to consider, especially in pharmacological applications. As a hydrochloride salt, this compound typically exhibits improved solubility in water compared to its free base form. Here are some key points about its solubility:

  • Water Solubility: Hydrochloride salts are generally more soluble in aqueous solutions, which enhances the bioavailability of the compound.
  • Organic Solvents: The compound may possess varying degrees of solubility in organic solvents; however, polar solvents like methanol and ethanol are likely to dissolve it effectively.
  • pH Dependence: The solubility may also be influenced by the pH of the solution, as its basic nature can interact with acidic conditions.

In summary, the 2-(methylamino)-1-phenyl-propan-1-ol;hydrochloride is anticipated to be highly soluble in water, facilitating its use in various formulations. This property is essential for effective therapeutic outcomes, as a soluble compound can more readily enter biological systems.

Interesting facts

Interesting Facts about 2-(Methylamino)-1-phenyl-propan-1-ol Hydrochloride

2-(Methylamino)-1-phenyl-propan-1-ol hydrochloride, commonly referred to in the scientific community due to its unique structure and properties, is a compound that has garnered attention for its various applications. Here are some notable features of this intriguing substance:

  • Pharmaceutical Relevance: This compound is primarily researched for its potential roles in the pharmaceutical industry. It can serve as an intermediate in the synthesis of various medicinal products.
  • CNS Activity: Compounds with similar structures are often studied for their central nervous system (CNS) activity, leading to investigations into their socio-psychological effects.
  • Reactivity: The presence of the methylamino group makes this compound an interesting candidate for various organic reactions, expanding the horizons for new synthesis strategies.
  • Stereochemistry: As a chiral molecule, 2-(methylamino)-1-phenyl-propan-1-ol hydrochloride can exhibit different biological activities depending on its stereochemistry, leading researchers to explore enantiomeric effects.

Moreover, the hydrochloride form enhances its solubility and stability, making it easier to work with in laboratory settings. The versatility of this compound reflects the ongoing innovations in organic chemistry and drug development.

From a student’s perspective, understanding this compound’s synthesis and its potential applications can be a fascinating exploration into the complexities of organic synthesis and medicinal chemistry. As one prominent chemist once stated, "Every compound tells a story, the question is, are you listening?"

Synonyms
Racephedrine hydrochloride
NIOSH/DO9540000
NSC-757308
56979-55-6
DO95400000
(+/-)-Eperisone hydrochloride
l-beta-Phenyl-beta-hydroxyisopropylmethylamine hydrochloride
(-)-alpha-(1-(Methylamino)ethyl)benzyl alcohol hydrochloride
Benzyl alcohol, alpha-(1-(methylamino)ethyl)-, hydrochloride, (-)-
dl-Pseudoephedrine hydrochloride
dl-Pseudoephedrine HCl
Ephedrine dl-form hydrochloride
Ephedrine hydrochloride, racemic
rac-Ephedrine Hydrochloride
SCHEMBL22823
SPECTRUM1500525
L-(-)-Ephedrine hydrochloride
CHEMBL3989464
BALXUFOVQVENIU-UHFFFAOYSA-N
HMS1920N22
Pharmakon1600-01500525
BCP24659
JLA66525
KLA97974
CCG-39247
NSC757308
AKOS015895235
FE01525
Benzenemethanol, alpha-(1-(methylamino)ethyl)-, hydrochloride, (R*,R*)-(+-)-
NCGC00094775-01
NCGC00094775-02
DB-042250
PSEUDOEPHEDRINE, (-)- HYDROCHLORIDE
(1R,2R)-2-(methylamino)-1-phenylpropan-1-ol hydrochloride
(1r,2s)-2-methylamino-1-phenyl-1-propanol hydrochloride
(1R,2R)-(-)-Pseudoephedrine-d3 hydrochloride (N-methyl-d3)
Benzenemethanol, .alpha.-[(1R)-1-(methylamino)ethyl]-, hydrochloride, (.alpha.S)-