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Ephedrine

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Identification
Molecular formula
C10H15NO
CAS number
299-42-3
IUPAC name
2-(methylamino)-1-phenyl-ethanol
State
State

At room temperature, ephedrine is typically a solid, presented as crystalline powder. It is stable under standard conditions but should be stored carefully to prevent decomposition or reaction with moisture and other chemicals.

Melting point (Celsius)
34.00
Melting point (Kelvin)
307.00
Boiling point (Celsius)
255.00
Boiling point (Kelvin)
528.00
General information
Molecular weight
165.24g/mol
Molar mass
165.2370g/mol
Density
1.1160g/cm3
Appearence

Ephedrine typically appears as a white, crystalline powder. It may also occur as colorless crystals. Being a stable compound, it maintains its appearance under standard conditions. However, its appearance may change if it is synthesized or mixed with other substances for pharmaceutical preparations.

Comment on solubility

Solubility of 2-(methylamino)-1-phenyl-ethanol (C10H15NO)

The solubility of 2-(methylamino)-1-phenyl-ethanol, a compound characterized by its unique structure, can be influenced by various factors. Understanding its solubility properties is crucial in different applications, including pharmaceuticals and organic chemistry. Here are some key points regarding its solubility:

  • Polar Nature: Due to the presence of both amine and hydroxyl functional groups, this compound exhibits polar characteristics which can enhance its solubility in polar solvents like water.
  • Solvent Interaction: The interaction between the solute and solvent is vital; for instance, in water, hydrogen bonding can facilitate the dissolution of this compound.
  • Temperature Dependency: Like many compounds, solubility often increases with temperature; hence, obtaining the solubility data at various temperatures is valuable.
  • pH Influence: The solubility may vary with pH changes. The presence of the amine group allows it to behave as a weak base, which can lead to different solubility levels in acidic versus basic environments.

In summary, while the exact solubility of 2-(methylamino)-1-phenyl-ethanol in specific solvents may need to be experimentally determined, its polar functional groups suggest that it will have significant solubility in polar solvents. As the saying goes, “like dissolves like,” indicating that this compound will likely interact favorably with other polar molecules.

Interesting facts

Interesting Facts about 2-(Methylamino)-1-phenyl-ethanol

2-(Methylamino)-1-phenyl-ethanol, often abbreviated as MAPE, is a fascinating compound with a broad range of applications, particularly in the field of pharmacology and organic chemistry. Here are some intriguing aspects of MAEP:

  • Biochemical Relevance: This compound is structurally related to various stimulant drugs. It is of interest for its potential impacts on neurotransmitter systems, particularly in relation to dopamine and norepinephrine, which are critical in mood regulation and cognitive function.
  • Synthetic Utility: MAEP serves as a viable intermediate in the synthesis of other organic compounds. Its unique structure allows it to participate in reactions that transform it into more complex molecules, making it valuable in synthetic organic chemistry.
  • Prodrug Consideration: Due to its ability to cross the blood-brain barrier, there is ongoing research into its effectiveness as a prodrug, which means it could be converted within the body into an active pharmacological agent.
  • Chemical Stability: The stability of this compound in various environments makes it a subject of study for drug formulation. Understanding how it behaves under different conditions is crucial for its practical applications.

In the words of a prominent chemist, “The exploration of compounds like MAEP is at the frontier of medicinal chemistry, where the smallest changes can lead to breakthroughs in treatment.” This highlights the importance of studying and understanding the molecular intricacies of compounds in the quest for innovative therapies.

Areas of Research

Research continues to evolve in several key areas:

  • Development of new therapeutic agents inspired by its structure.
  • Investigations into its pharmacokinetics and pharmacodynamics.
  • Studies on its effects in potential neurological applications.

Overall, 2-(Methylamino)-1-phenyl-ethanol exemplifies how a single compound can hold the key to numerous scientific advances, making it a vital topic within chemistry and related disciplines.

Synonyms
2-(Methylamino)-1-phenylethanol
6589-55-5
N-methylphenylethanolamine
2-(methylamino)-1-phenylethan-1-ol
68579-60-2
(+-)-Halostachine
Halostachine
2-Methylamino-1-phenyl-ethanol
dl-alpha-(Methylaminomethyl)benzyl alcohol
2-Methylamino-1-phenylethanol
alpha-(Methylaminomethyl)benzyl alcohol
(+-)-alpha-((Methylamino)methyl)benzenemethanol
(+/-)-halostachine
Ethanol, 2-(methylamino)-1-phenyl-
WIN 5529-2
dl-Halostachine
alpha-((Methylamino)methyl)benzyl alcohol
Benzyl alcohol, alpha-((methylamino)methyl)-, dl-
EINECS 229-525-5
BRN 1072841
CHEBI:16913
dl-1-Phenyl-1-oxy-2-(methylamino)-aethan [German]
Benzenemethanol, alpha-((methylamino)methyl)-, (+-)-
MFCD00004506
U7B63FX8CH
dl-1-Phenyl-1-oxy-2-(methylamino)-aethan
4-13-00-01802 (Beilstein Handbook Reference)
BENZYL ALCOHOL, alpha-((METHYLAMINO)METHYL)-
alpha-[(Methylamino)methyl]benzyl alcohol
alpha-[(Methylamino)methyl]-benzyl alcohol
Benzenemethanol, .alpha.-[(methylamino)methyl]-
alpha-((Methylamino)methyl)-benzyl alcohol
benzene, (1-hydroxy-2-methylamino)ethyl-
UNII-U7B63FX8CH
BENZENEMETHANOL, .ALPHA.-((METHYLAMINO)METHYL)-
Dl-alpha-(methylaminomethyl)benzylalcohol
MPEOA
bmse000396
SCHEMBL210960
CHEMBL1241267
DTXSID90988242
HALOSTACHINE, (+/-)-
a-(Methylaminomethyl)benzyl alcohol
AAA49542
ALBB-031903
BCP22653
GAA58955
(2-hydroxy-2-phenylethyl)methylamine
+/--(Methylaminomethyl)benzyl alcohol
AKOS005207037
SB38173
alpha -(Methylaminomethyl)benzyl alcohol
alpha-(methylaminomethyl)-benzyl alcohol
alpha-[(methylamino)methyl]benzenemethanol
SY078893
TS-02000
1-PHENYL-2-(N-METHYLAMINO)ETHANOL
DB-356253
.alpha.-((Methylamino)methyl)benzyl alcohol
CS-0204443
METHYL(2-HYDROXY-2-PHENYLETHYL)AMINE
NS00046990
alpha-((methylamino)methyl)-dl-Benzyl alcohol
alpha-(Methylaminomethyl)benzyl alcohol, 99%
C03711
G77268
N-METHYL-.BETA.-HYDROXYLPHENYLETHYLAMINE
.ALPHA.-(METHYLAMINOMETHYL)BENZYL ALCOHOL
Benzyl alcohol, .alpha.-((methylamino)methyl)-
EN300-1251177
BRD-A79058669-001-01-1
Q27102132