Interesting facts
Interesting Facts about 2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
This fascinating compound, with its unique structure, boasts several intriguing characteristics likely to capture the attention of chemists and students alike.
Key Features
- Pharmacological Significance: Many amides like this one are known to play crucial roles in medicinal chemistry. They often act as intermediates in the synthesis of pharmaceuticals and can possess biological activity.
- Functional Groups: The presence of a nitro group and a trifluoromethyl group is particularly noteworthy. The nitro group can impart electron-withdrawing properties, which can be pivotal in modifying the reactivity of the compound.
- Trifluoromethyl Influence: The trifluoromethyl group is recognized for its ability to enhance the lipophilicity and metabolic stability of compounds, often enhancing the overall pharmacokinetic profile.
Applications in Research
Researchers are increasingly exploring compounds of this nature for their potential in fields such as:
- Agricultural Chemistry: Compounds with similar structures have been scrutinized for their efficacy as herbicides or pesticides.
- Material Science: The unique properties conferred by fluorinated compounds open avenues in creating novel materials that require specific thermal and chemical resistance.
- Biochemistry: Such compounds may also serve as tools for probing biological processes or pathways owing to their structural complexity and reactivity.
Conclusion
Overall, 2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide exemplifies how chemical modifications can lead to a myriad of applications across different scientific disciplines. As we continue to delve deeper into the properties and possibilities of chemical compounds, this aromatic amide stands out as a valuable compound for further exploration.
Synonyms
flutamide
13311-84-7
Niftolide
Eulexin
Niftholide
niftolid
NFBA
2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
Sch 13521
Drogenil
Flutamida
Cebatrol, veterinary
Flutamidum
Flutamin
4'-Nitro-3'-trifluoromethylisobutyranilide
Sch-13521
Ham's F-12 medium
N-(4-NITRO-3-(TRIFLUOROMETHYL)PHENYL)ISOBUTYRAMIDE
Flutamidum [INN-Latin]
2-Methyl-N-(4-nitro-3-[trifluoromethyl]phenyl)propanamide
Flutamida [INN-Spanish]
Propanamide, 2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-
SCH13521
MFCD00072009
CCRIS 7246
NSC 215876
alpha,alpha,alpha-Trifluoro-2-methyl-4'-nitro-m-propionotoluidide
EINECS 236-341-9
NSC-215876
BRN 2157663
CHEBI:5132
Propanamide, 2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)-
DTXSID7032004
UNII-76W6J0943E
CHEMBL806
76W6J0943E
4-Nitro-3-(trifluoromethyl)isobutyranilide
2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propionamide
DTXCID9011121
Flutamide [USAN:USP:INN:BAN]
NCGC00015452-09
Eulexine
Chimax
4'-Nitro-3'-trifluoromethylisobutyramilide
Flutamidum (INN-Latin)
CAS-13311-84-7
m-Propionotoluidide, 2-methyl-4'-nitro-alpha,alpha,alpha-triflouro-
m-Propionotoluidide, alpha,alpha,alpha-trifluoro-2-methyl-4'-nitro-
Flutamida (INN-Spanish)
FLUTAMIDE (MART.)
FLUTAMIDE [MART.]
FLUTAMIDE (USP-RS)
FLUTAMIDE [USP-RS]
Flutamide USP25
FLUTAMIDE (EP IMPURITY)
FLUTAMIDE [EP IMPURITY]
FLUTAMIDE (EP MONOGRAPH)
FLUTAMIDE [EP MONOGRAPH]
FLUTAMIDE (USP MONOGRAPH)
FLUTAMIDE [USP MONOGRAPH]
Flutamide (USAN:USP:INN:BAN)
Prostandril
Odyne
.alpha.,.alpha.,.alpha.-Trifluoro-2-methyl-4'-nitro-m-propionotoluidide
SMR000058187
Eulexin (TN)
m-Propionotoluidide,.alpha.,.alpha.-trifluoro-
SR-01000075888
N-[4-Nitro-3-(trifluoromethyl)phenyl]isobutyramide
2-Methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)propanamide
Flutamid
.alpha.,.alpha.-Trifluoro-2-methyl-4'-nitro-m-propionotoluidide
m-Propionotoluidide,.alpha.,.alpha.-trifluoro-2-methyl-4'-nitro-
4'-Nitro-3'-(trifluoromethyl)isobutyranilide
Flutamide,(S)
Prestwick_228
Flutamide (Eulexin)
NK-601
Flutamide (Standard)
Spectrum_001210
CPD000058187
FLUTAMIDE [INN]
FLUTAMIDE [JAN]
FLUTAMIDE [MI]
FLUTAMIDE [USAN]
Prestwick0_000180
Prestwick1_000180
Prestwick2_000180
Prestwick3_000180
Spectrum2_001201
Spectrum3_001421
Spectrum4_000829
Spectrum5_001450
Lopac-F-9397
F0663
Flutamide (pubertal study)
F 9397
FLUTAMIDE [WHO-DD]
SCHEMBL3934
Lopac0_000557
BSPBio_000079
BSPBio_003122
KBioGR_001377
KBioSS_001690
MLS000069634
MLS001065596
MLS002548892
DivK1c_000459
SPECTRUM1500995
Flutamide - Bio-X trade mark
SPBio_000982
SPBio_002000
Flutamide (JP18/USP/INN)
BPBio1_000087
GTPL6943
FLUTAMIDE [ORANGE BOOK]
CHEMBL4759307
SCHEMBL12932289
HMS501G21
HY-B0022R
KBio1_000459
KBio2_001690
KBio2_004258
KBio2_006826
KBio3_002342
L02BB01
NINDS_000459
HMS1568D21
HMS1921O16
HMS2090I18
HMS2092O14
HMS2095D21
HMS2230P19
HMS3259I03
HMS3261P15
HMS3373C12
HMS3655G22
HMS3712D21
Pharmakon1600-01500995
BCP23006
HY-B0022
YIA13472
Tox21_110154
Tox21_202169
Tox21_300536
Tox21_500557
BDBM50131270
CCG-39105
NSC147834
NSC215876
NSC757817
s1908
AKOS001025465
AKOS015994751
AKOS025243203
m-Propionotoluidide, .alpha.,.alpha.,.alpha.-trifluoro-2-methyl-4'-nitro-
Tox21_110154_1
AB02835
DB00499
FF23510
KS-5091
LP00557
NC00451
NSC-147834
NSC-757817
SDCCGSBI-0050540.P004
IDI1_000459
NCGC00015452-01
NCGC00015452-02
NCGC00015452-03
NCGC00015452-04
NCGC00015452-05
NCGC00015452-06
NCGC00015452-07
NCGC00015452-08
NCGC00015452-10
NCGC00015452-11
NCGC00015452-12
NCGC00015452-13
NCGC00015452-14
NCGC00015452-15
NCGC00015452-16
NCGC00015452-19
NCGC00015452-20
NCGC00015452-32
NCGC00091460-01
NCGC00091460-02
NCGC00091460-03
NCGC00091460-04
NCGC00091460-05
NCGC00091460-06
NCGC00091460-07
NCGC00091460-08
NCGC00091460-09
NCGC00254495-01
NCGC00259718-01
NCGC00261242-01
AC-24192
BF166239
SY036411
SBI-0050540.P003
DB-042163
3'-Trifluoromethyl-4'-Nitro-Isobutyranilide
AB00052188
EU-0100557
NS00002675
SW196536-4
4''-nitro-3''-trifluoromethylisobutyranilide
A10796
C07653
D00586
EN300-119548
AB00052188-09
AB00052188_10
AB00052188_11
Q418669
SR-01000075888-1
SR-01000075888-6
SR-01000075888-7
SR-01000075888-9
BRD-K28307902-001-05-0
BRD-K28307902-001-20-9
BRD-K28307902-001-21-7
Flutamide, certified reference material, TraceCERT(R)
Z56755651
Flutamide, European Pharmacopoeia (EP) Reference Standard
N1-[4-nitro-3-(trifluoromethyl)phenyl]-2-methylpropanamide
2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide #
Flutamide, United States Pharmacopeia (USP) Reference Standard
alpha,alpha,alpha-trifluoro-2-methyl-4''-nitro-m-propionotoluidide
m-Propionotoluidide, 2-methyl-4'-nitro-.alpha.,.alpha.,.alpha.-trifluoro-
Flutamide for system suitability, European Pharmacopoeia (EP) Reference Standard
2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide;N-(Isopropylcarbonyl)-4-nitro-3-trifluoromethylaniline;4'-Nitro-3'-trifluo romethylisobutyranilide
236-341-9
37209-54-4
Solubility of 2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
The solubility of 2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide (C11H11F3N2O3) is influenced by various factors due to its unique chemical structure. Understanding its solubility is important for applications in pharmaceuticals and chemical manufacturing. Here are key points to consider:
In conclusion, the solubility of this compound can be categorized as moderately soluble in polar solvents while being more soluble in organic solvents. Therefore, conducting solubility tests in different media is advisable for accurate application and formulation analyses.