Interesting facts
Interesting Facts about 2-Methyl-3-(o-tolyl)quinazolin-4-one
2-Methyl-3-(o-tolyl)quinazolin-4-one is a fascinating compound that belongs to the quinazolinone family, which is recognized for its wide range of biological and pharmacological activities. Here are some compelling aspects of this compound:
- Biological Significance: Compounds in the quinazolinone series have been studied for their potential in medicinal chemistry, illustrating properties such as anticancer, antimicrobial, and anti-inflammatory effects. This positions 2-methyl-3-(o-tolyl)quinazolin-4-one as a promising candidate in drug development.
- Synthetic Versatility: The presence of both methyl and tolyl groups in its structure not only enhances its reactivity but also allows for various synthetic pathways to create derivatives. This can be advantageous in optimizing its bioactivity.
- Structure-Activity Relationship (SAR): Research on 2-methyl-3-(o-tolyl)quinazolin-4-one provides insights into how structural modifications can influence its pharmacological properties, offering a rich field for exploration.
- Fluorescent Properties: Some quinazolinone derivatives exhibit notable fluorescence, which can be utilized in biological assays and imaging techniques, enhancing their applicability in research settings.
- Research Opportunities: Due to its structural characteristics, this compound is an intriguing subject for studies aimed at understanding its mechanism of action, optimization methods, and interactions with biological targets.
As this compound continues to inspire scientific exploration, it reinforces the critical intersection between organic chemistry and pharmaceutical development, illustrating the potential of small molecules in the ongoing quest for therapeutic agents.
“The beauty of chemistry lies in the endless possibilities for discovery.”
Synonyms
METHAQUALONE
Metolquizolone
Quaalude
72-44-6
Methaqualoneinone
Metaqualon
Ortonal
Metakvalon
Methaqualon
Tuazolone
Cateudyl
Melsomin
Tuazole
Aqual
Dormigoa
Dormogen
Dormutil
Dorsedin
Fadormir
Holodorm
Mollinox
Mozambin
Nobedorm
Noctilene
Optinoxan
Orthonal
Parminal
Rouqualone
Sindesvel
Somberol
Somnomed
Hyminal
Hypocol
Hyptor
Ipnofil
Melsed
Motolon
Roulone
Soverin
Torinal
Omnyl
Sonal
Sopor
Hyptor base
Normi-Nox
Methased
Citexal
Mequin
Revonal
Melsedin base
Pro-dorm
Dormigoa-Schlafmittel
MAOA
Methachalonum
Rorer 148
Rorer 714
Somnafac
3,4-Dihydro-2-methyl-4-oxo-3-o-tolylquinazoline
Nethaqualone
Metachalon
Metacualona
Methyl-o-tolylquinazolone
2-Methyl-3-(2-methylphenyl)-4(3H)-quinazolinone
2-Methyl-3-o-tolyl-4-quinazolone
2-Methyl-3-tolyl-4-oxybensdiazine
CN 38703
QZ 2
2-Methyl-3-o-tolyl-4(3H)-quinazolinone
CI-705
Metaqualone
Methaqualonum
TR-495
Hypcol
2-Methyl-3-(2-tolyl)quinazol-4-one
RIC 272
R-148
2-Methyl-3-o-tolyl-4(3H)-chinazolone
4(3H)-Quinazolinone, 2-methyl-3-(2-methylphenyl)-
QZ-2
2-Methyl-3-(2-methylphenyl)-4-quinazolinone
2-Methyl-3-(o-tolyl)-3,4-dihydro-4-quinazolinone
HSDB 3120
UNII-7ZKH8MQW6T
2-Methyl-3-o-tolyl-4(3H)-chinazolinon
7ZKH8MQW6T
EINECS 200-780-4
4(3H)-Quinazolinone, 2-methyl-3-o-tolyl-
NSC 111388
NSC-111388
NSC-126877
NSC-631628
BRN 0211874
CHEBI:6821
DTXSID7023279
MTQ
TR 495
CN-38703
DTXCID403279
Methaqualone-d5
5-24-03-00132 (Beilstein Handbook Reference)
2-methyl-3-(2-methylphenyl)quinazolin-4(3H)-one
CI 705
NSC126877
NSC631628
2-methyl-3-(o-tolyl)quinazolin-4-one
Metachalon [Czech]
NSC-111388-
NCGC00245236-02
METHAQUALONE (MART.)
METHAQUALONE [MART.]
Metacualona [INN-Spanish]
Methaqualonum [INN-Latin]
(2-Methyl-3-(o-tolyl)-3,4-dihydro-4-(quinazolinone)
METHAQUALONE (EP IMPURITY)
METHAQUALONE [EP IMPURITY]
Tuazol
CAS-72-44-6
WLN: T66 BVN ENJ CR B1& D1
2-Methyl-3-o-tolyl-4(3H)-chinazolinon [German]
Reposil
DEA No. 2565
Methaqualone [USAN:USP:INN:BAN]
1184966-71-9
A1ADG
METHAQUALONE [MI]
2-Methyl-3-(o-tolyl)quinazolin-4(3H)-one
(.+/-.)-Methaqualone
METHAQUALONE [INN]
METHAQUALONE [JAN]
METHAQUALONE [HSDB]
METHAQUALONE [USAN]
METHAQUALONE [VANDF]
SCHEMBL43892
MLS000678342
METHAQUALONE [WHO-DD]
CHEMBL282052
N05CM01
RIC-272
Methaqualone, 1mg/ml in Methanol
4(3H)-Quinazolinone, 2-methyl-3-(2-methylphenyl)-, (-)-
HMS2626L18
Methaqualone 0.1 mg/ml in Methanol
Methaqualone 1.0 mg/ml in Methanol
Tox21_112502
Tox21_112869
2-Methyl-3-o-tolylquinazolin-4-one
NSC111388
STL386501
AKOS000509786
DB04833
NCGC00245236-01
SMR000285241
2-methyl-3-(o-tolyl)-3H-quinazolin-4-one
NS00006468
4(3H)-Quinazolinone, 2-methyl-3-o--tolyl-
C07560
D00557
2-methyl-3-(o-tolyl)-quinazoline-4 (3H)-one
Q423912
200-780-4
MQL
Solubility of 2-methyl-3-(o-tolyl)quinazolin-4-one (C16H14N2O)
The solubility of 2-methyl-3-(o-tolyl)quinazolin-4-one is an intriguing topic, primarily due to its unique structural characteristics. This compound is moderately soluble in various organic solvents but exhibits limited solubility in water. The solubility can be influenced by several factors including:
It is worth noting that solubility data can vary with impurities or the presence of other chemical entities. Detailed investigation into solubility provides insights into the possible applications of this compound in pharmaceuticals and materials science. As stated by researchers, "Understanding solubility is crucial for the effective use of chemical compounds in various scenarios."