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Procaine

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Identification
Molecular formula
C13H20N2O2
CAS number
59-46-1
IUPAC name
[2-methyl-2-(propylamino)propyl] benzoate
State
State

Procaine is a solid at room temperature. It is often used or administered in its hydrochloride form, which is also a solid but more soluble in water, allowing for medical use in solutions.

Melting point (Celsius)
61.00
Melting point (Kelvin)
334.15
Boiling point (Celsius)
411.50
Boiling point (Kelvin)
684.65
General information
Molecular weight
236.32g/mol
Molar mass
236.3150g/mol
Density
1.1000g/cm3
Appearence

Procaine typically appears as a white, crystalline powder. It is often processed into its hydrochloride form, known as procaine hydrochloride, which is more commonly used. This compound is odorless and has a very faint, sour taste.

Comment on solubility

Solubility of [2-methyl-2-(propylamino)propyl] benzoate

The solubility of [2-methyl-2-(propylamino)propyl] benzoate (C13H20N2O2) can be quite intriguing due to its unique structure. This compound is characterized by the presence of both a hydrophobic aromatic group (the benzoate part) and a hydrophilic amine group. Consequently, the solubility properties can exhibit variability based on environmental conditions.

Factors Influencing Solubility:

  • Polarity: The presence of polar amine groups typically increases solubility in polar solvents such as water, while the hydrophobic aromatic region may favor solubility in non-polar solvents.
  • Temperature: Generally, solubility of solids in liquids increases with increasing temperature, which may enhance the solubility of this compound in suitable solvents.
  • pH of the Solution: The ionization of the amine group can depend on the pH, altering its solubility characteristics. In acidic conditions, it is more likely to be protonated, potentially increasing its solubility in water.
  • Solvent Selection: It is important to choose an appropriate solvent; for example, organic solvents might solubilize this compound more effectively due to the non-polar nature of the benzoate moiety.

In summary, the solubility of [2-methyl-2-(propylamino)propyl] benzoate is influenced by a combination of its molecular structure and external conditions. It is essential to consider these factors when investigating its solubility characteristics in various solvents.

Interesting facts

Interesting Facts about [2-methyl-2-(propylamino)propyl] benzoate

[2-methyl-2-(propylamino)propyl] benzoate is an intriguing compound with a variety of applications, primarily in the field of organic chemistry and pharmaceuticals. Here are some fascinating insights:

  • Structural Insights: The compound features an aromatic benzoate backbone, which is attached to a branched alkyl chain containing a propylamino group. This unique structure contributes to its diverse properties and functionalities.
  • Pharmaceutical Relevance: Compounds like [2-methyl-2-(propylamino)propyl] benzoate are often studied for their potential *therapeutic effects,* especially in the formulation of certain medications. This structural complexity can impact how drugs interact with biological systems.
  • Synthetic Pathways: The synthesis of this compound can be achieved through various methods, including chemical modifications of simpler precursors. Understanding these pathways is crucial for manufacturing in both academic and industrial settings.
  • Analytical Techniques: Chemists often employ techniques such as NMR (Nuclear Magnetic Resonance) and IR (Infrared Spectroscopy) to analyze the structure and purity of [2-methyl-2-(propylamino)propyl] benzoate. These methods allow for detailed insights into the molecular characteristics.
  • Potential Applications: Beyond pharmaceuticals, this compound may have applications in *agriculture* as a pesticide or herbicide, or even in the manufacturing of fragrances due to its aromatic nature.

As a student of chemistry, one can appreciate how such compounds illustrate the beauty of molecular complexity and the importance of interdisciplinary applications. Each intriguing feature and potential application underscores the essential role of chemical compounds in advancing both science and technology.

Synonyms
MEPRYLCAINE
Oracaine
Epirocaine
Epirocain
495-70-5
Meprylcaine [INN]
Meprilcaino
Meprylcainum
[2-methyl-2-(propylamino)propyl] benzoate
Meprylcainum [INN-Latin]
Meprilcaino [INN-Spanish]
meprilcaina
UNII-82YT7WU9PW
82YT7WU9PW
2-Methyl-2-(propylamino)-1-propanol benzoate
BRN 2581683
MEPRYLCAINE [MI]
Benzoesaeure-(2-methyl-2-propylaminopropylester)
1-Propanol, 2-methyl-2-(propylamino)-, benzoate
MEPRYLCAINE [WHO-DD]
DTXSID70197810
4-09-00-00565 (Beilstein Handbook Reference)
2-Methyl-2-(propylamino)-1-propanol benzoate (ester)
1-Propanol, 2-methyl-2-(propylamino)-, benzoate (ester)
Oracaine (TN)
2-METHYL-2-PROPYLAMINOPROPYL BENZOATE
Meprylcainum (INN-Latin)
Meprilcaino (INN-Spanish)
1-PROPANOL-2-METHYL-2-(PROPYLAMINO)-, BENZOATE (ESTER)
.BETA.-(N-PROPYLAMINO)-.BETA.,.BETA.-DIMETHYLETHYL BENZOATE
NCGC00016551-01
CAS-956-03-6
Prestwick0_001064
Prestwick1_001064
Prestwick2_001064
Prestwick3_001064
SCHEMBL24631
BSPBio_001048
SPBio_002964
BPBio1_001154
CHEMBL127810
CHEBI:93147
DTXCID30120301
BDBM50225703
NCGC00016551-02
2-Methyl-2-(propylamino)propyl benzoate #
AB00514705
NS00096963
AB00514705_06
Q6817839
benzoic acid [2-methyl-2-(propylamino)propyl] ester
BRD-K65417056-003-03-6
BRD-K65417056-003-10-1
1-Propanol, 2-methyl-2-(propylamino)-, benzoate (7CI)
BETA-(N-PROPYLAMINO)-BETA,BETA-DIMETHYLETHYL BENZOATE