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2-methyl-1,2-bis(3-pyridyl)propan-1-one

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Identification
Molecular formula
C14H14N2O
CAS number
13171-25-0
IUPAC name
2-methyl-1,2-bis(3-pyridyl)propan-1-one
State
State

At room temperature, this compound is typically a solid. It is relatively stable under standard storage conditions, although it should be handled with care to avoid exposure to moisture and light which can induce degradation.

Melting point (Celsius)
157.00
Melting point (Kelvin)
430.15
Boiling point (Celsius)
376.50
Boiling point (Kelvin)
649.65
General information
Molecular weight
220.28g/mol
Molar mass
220.2820g/mol
Density
1.2730g/cm3
Appearence

The compound typically appears as a crystalline solid with a white to off-white color. It may form larger aggregates or powdered form depending on the synthesis method used.

Comment on solubility

Solubility of 2-methyl-1,2-bis(3-pyridyl)propan-1-one

The compound 2-methyl-1,2-bis(3-pyridyl)propan-1-one, with the chemical formula C14H14N2O, showcases interesting solubility characteristics that can be quite beneficial in various applications. Here are several key points regarding its solubility:

  • Solvent Compatibility: This compound generally exhibits good solubility in polar organic solvents such as methanol, ethanol, and acetone. This is primarily due to the presence of the carbonyl group, which enhances dipole interactions.
  • Limited Water Solubility: Despite the presence of nitrogen atoms in its structure, which could contribute to hydrogen bonding, 2-methyl-1,2-bis(3-pyridyl)propan-1-one has limited solubility in water. This is likely attributed to its relatively hydrophobic hydrocarbon framework.
  • Temperature Dependence: The solubility of this compound can vary with temperature; typically, higher temperatures increase solubility in organic solvents, making it essential to consider thermal conditions during dissolution.
  • pH Influence: In some cases, altering the pH of the solution can enhance solubility by modifying the ionization states of the nitrogen atoms in the pyridine rings, particularly in basic conditions.

In summary, while 2-methyl-1,2-bis(3-pyridyl)propan-1-one demonstrates favorable solubility in certain organic solvents, its limited water solubility poses challenges for applications needing aqueous environments. Understanding these solubility aspects can significantly influence its utilization in pharmaceutical and chemical synthesis sectors.

Interesting facts

Interesting Facts about 2-methyl-1,2-bis(3-pyridyl)propan-1-one

2-methyl-1,2-bis(3-pyridyl)propan-1-one, often referred to in scientific circles as a fascinating compound due to its unique structural characteristics and potential applications. Here are some intriguing aspects of this compound:

  • Molecular Structure: This compound features a complex structure that includes two pyridine rings. The presence of these heterocyclic aromatic rings contributes to its chemical reactivity and stability.
  • Biological Activity: Compounds like 2-methyl-1,2-bis(3-pyridyl)propan-1-one have been studied for their potential therapeutic properties, especially in the fields of pharmacology and medicinal chemistry. Researchers are actively exploring its role as a potential anti-cancer agent.
  • Synthesis: The synthesis of this compound can involve various methods, including multistep organic synthesis, which highlights the creativity and precision of modern chemistry techniques.
  • Applications: Beyond its biological applications, compounds with similar structures are often used in agrochemicals and pesticides, showcasing the versatility and importance of such chemistries in different industries.
  • Interesting Reactions: Its reactivity with different nucleophiles and electrophiles can lead to a variety of complex chemical reactions, making it a compound of interest for organic chemists.

In conclusion, 2-methyl-1,2-bis(3-pyridyl)propan-1-one not only represents an intriguing case study in organic chemistry but also opens new avenues for research into its practical applications in health and industry. As scientists continue to investigate its properties, who knows what new discoveries lie ahead?

Synonyms
metyrapone
54-36-4
2-Methyl-1,2-di-3-pyridyl-1-propanone
Metopirone
Methopyrapone
Metopiron
Methapyrapone
Methopirapone
Methopyrinine
Methopyrone
Metopyrone
Metyrapon
Methbipyranone
Mepyrapone
Metirapona
Metroprione
Metapirone
Metyraponum
Metapyron
2-methyl-1,2-dipyridin-3-ylpropan-1-one
1-Propanone, 2-methyl-1,2-di-3-pyridinyl-
Su 4885
Metyraponum [INN-Latin]
2-methyl-1,2-di(pyridin-3-yl)propan-1-one
Metirapona [INN-Spanish]
2-Methyl-1,2-di-3-pyridinyl-1-propanone
2-Methyl-1,2-bis(3-pyridyl)-1-propanone
NSC 25265
HSDB 2500
1,2-Di-3-pyridyl-2-methyl-1-propanone
UNII-ZS9KD92H6V
1-Propanone, 2-methyl-1,2-di-3-pyridyl-
EINECS 200-206-2
ZS9KD92H6V
NSC-25265
DTXSID1023314
CHEBI:44241
1-Propanone, 1,2-di-3-pyridyl-2-methyl-
2-methyl-1,2-bis(pyridin-3-yl)propan-1-one
CHEMBL934
DTXCID803314
2-methyl-1,2-dipyridin-3-yl-propan-1-one
NSC25265
Metyrapone [USAN:USP:INN:BAN:JAN]
CAS-54-36-4
NCGC00016242-01
Metyraponum (INN-Latin)
Metirapona (INN-Spanish)
METYRAPONE (MART.)
METYRAPONE [MART.]
METYRAPONE (USP-RS)
METYRAPONE [USP-RS]
MYT
METYRAPONE (USP MONOGRAPH)
METYRAPONE [USP MONOGRAPH]
Metyrapone (USAN:USP:INN:BAN:JAN)
SMR000059134
METOPIRONE (TN)
MFCD00006397
Metyrapone (Standard)
METYRAPONE [MI]
METYRAPONE [INN]
METYRAPONE [JAN]
Prestwick0_000904
Prestwick1_000904
Prestwick2_000904
Prestwick3_000904
METYRAPONE [HSDB]
METYRAPONE [USAN]
METYRAPONE [VANDF]
METYRAPONE [WHO-DD]
BIDD:PXR0082
BSPBio_000748
MLS001066377
MLS001335881
MLS001335882
SCHEMBL637432
SPBio_002947
1-Propanone,2-di-3-pyridyl-
BPBio1_000824
GTPL5224
Metyrapone (JP18/USP/INN)
METYRAPONE [ORANGE BOOK]
1-Propanone,2-di-3-pyridinyl-
HY-B1232R
V04CD01
HMS1570F10
HMS2094I07
HMS2097F10
HMS2235E16
HMS3259O05
HMS3371B16
HMS3714F10
HMS3742E21
HMS3869K13
Pharmakon1600-01506014
BCP19099
EX-A1403
HY-B1232
Tox21_110323
BDBM50028166
NSC760076
s5416
AKOS015919707
Metyrapone, >=98% (HPLC), solid
Tox21_110323_1
CCG-213598
CS-4879
DB01011
NC00462
NSC-760076
NCGC00016242-02
NCGC00016242-03
NCGC00016242-05
NCGC00161837-01
AS-56195
DB-052546
AB00513955
EU-0009322
NS00010555
Su-4885; Su 4885; Su4885
2-Methyl-1,2-di(3-pyridinyl)-1-propanone #
C07205
D00410
D70339
2-Methyl-1,2-di-3-pyridyl-1-propanone, 96%
AB00513955_07
EN300-18532278
Q821641
SR-01000765398
1-PROPANONE, 2-METHYL-1,2-DI-3-PYRIDINYL
SR-01000765398-2
BRD-K46862739-001-03-6
BRD-K46862739-001-13-5
BRD-K46862739-001-14-3
Z2289798161
Metyrapone, United States Pharmacopeia (USP) Reference Standard
200-206-2