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Propranolol Hydrochloride

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Identification
Molecular formula
C15H22ClNO3
CAS number
4199-08-0
IUPAC name
2-(isopropylamino)-1-(4-nitrophenyl)ethanol;hydrochloride
State
State

At room temperature, propranolol hydrochloride exists as a solid. It is used primarily in the pharmaceutical industry and may be found as powder or as part of tablet formulations.

Melting point (Celsius)
163.00
Melting point (Kelvin)
436.15
Boiling point (Celsius)
370.00
Boiling point (Kelvin)
643.15
General information
Molecular weight
295.81g/mol
Molar mass
295.8060g/mol
Density
1.3075g/cm3
Appearence

Propranolol hydrochloride appears as a white or almost white crystalline powder. It is odorless and has a bitter taste. The compound is hygroscopic and should be stored carefully to maintain its powdery texture.

Comment on solubility

Solubility of 2-(isopropylamino)-1-(4-nitrophenyl)ethanol; hydrochloride

The solubility of 2-(isopropylamino)-1-(4-nitrophenyl)ethanol; hydrochloride, with the chemical formula C15H22ClNO3, is an important aspect to consider for its applications and handling. Here are some key points regarding its solubility:

  • Hydrochloride Salt Formation: Being a hydrochloride, this compound tends to be more soluble in water compared to its base form due to the presence of the Cl- ion.
  • Polar Nature: The molecule contains both polar and non-polar regions. The presence of the -NH2 group increases hydrophilicity, aiding solubility in polar solvents.
  • Solvent Dependence: It is usually more soluble in polar solvents, particularly water and alcohols, whereas solubility in non-polar solvents may be considerably lower.
  • Thermodynamic Factors: Solubility is influenced by temperature and pH levels; increasing temperature typically enhances solubility of such ionic compounds.

In conclusion, the solubility characteristics of this compound highlight its potential for utilization in aqueous environments. As a **hydrochloride salt**, it is designed for optimal solubility, making it favorable in various biochemical applications.

Interesting facts

Interesting Facts about 2-(Isopropylamino)-1-(4-nitrophenyl)ethanol; Hydrochloride

This fascinating compound belongs to a category of chemicals known for their diverse biological activities. Here are some compelling points of interest:

  • Pharmacological Relevance: 2-(Isopropylamino)-1-(4-nitrophenyl)ethanol; hydrochloride is recognized for its potential in medicinal chemistry. Compounds that are structurally similar often exhibit properties that can be harnessed for therapeutic applications.
  • Structure-Activity Relationship (SAR): The presence of the 4-nitrophenyl group is crucial. This nitro substitution can enhance the compound's ability to interact with biological targets, which makes it a subject of study for developing new drugs.
  • Biological Interaction: It is believed to interact with specific enzymes and receptors, influencing various biological pathways. This property is what makes it particularly valuable in pharmaceutical research.
  • Research Potential: Scientists often explore this compound within the frameworks of both molecular biology and drug design, investigating how modifications can lead to enhanced efficacy or reduced toxicity.

As a student or scientist, delving into the world of compounds like 2-(isopropylamino)-1-(4-nitrophenyl)ethanol; hydrochloride opens doors to numerous research opportunities. "The study of chemical compounds is not just about their structure, but also about the stories they tell in our bodies and the world around us," as many chemists would say. The continued exploration of such compounds is vital for the advancement of medicine and the understanding of biochemical processes.

Synonyms
Nifenalol hydrochloride
5704-60-9
Nifenalol HCl
1-(4-Nitrophenyl)-1-hydroxy-2-isopropylaminoethane hydrochloride
2-(Isopropylamino)-1-(p-nitrophenyl)ethanol hydrochloride
INPEA
Nifenalol (hydrochloride)
2KMT7J8EZC
74-10-2
5704-60-9 (HCl)
1-(4-nitrophenyl)-2-(propan-2-ylamino)ethanol;hydrochloride
(+-)-2-(Isopropylamino)-1-(p-nitrophenyl)ethanol hydrochloride
Nifenalol?
UNII-2KMT7J8EZC
INPEA HYDROCHLORIDE
ETHANOL, 2-(ISOPROPYLAMINO)-1-(p-NITROPHENYL)-, HYDROCHLORIDE
(+-)-INPEA hydrochloride
DL-INPEA HYDROCHLORIDE
SCHEMBL9118298
CHEMBL3250258
DTXSID90972520
GLXC-10046
(+/-)-INPEA HYDROCHLORIDE
EX-A1219
EINECS 227-194-1
NIFENALOL HYDROCHLORIDE [MI]
AKOS030228528
(+/-)-NIFENALOL HYDROCHLORIDE
NIFENALOL HYDROCHLORIDE [WHO-DD]
AC-36837
AS-79011
DA-66089
HY-100952
CS-0020620
A11571
EN300-23543183
1-p-nitrophenyl-2-isopropylamino-ethanol-hydrochloride
Q27254875
N-ISOPROPYL-P-NITROPHENYLETHANOLAMINE HYDROCHLORIDE
1-(4-NITROPHENYL)-1-HYDROXY-2-ISOPROPYLAMINOETHANE HCL
DL-N-ISOPROPYL-P-NITROPHENYLETHANOLAMINE HYDROCHLORIDE
1-(4-NITROPHENYL)-2-(ISOPROPYLAMINO)ETHANOL HYDROCHLORIDE
1-(4-nitrophenyl)-2-[(propan-2-yl)amino]ethan-1-ol hydrochloride
1-(P-NITROPHENYL)-2-(ISOPROPYLAMINO)ETHANOL HYDROCHLORIDE
DL-2-(ISOPROPYLAMINO)-1-(P-NITROPHENYL)ETHANOL HYDROCHLORIDE
(+/-)-1-(4-NITROPHENYL)-2-(ISOPROPYLAMINO)ETHANOL HYDROCHLORIDE
(+/-)-1-(4-NITROPHENYL)-2-ISOPROPYLAMINOETHANOL HYDROCHLORIDE
(1)-alpha-((Isopropylamino)methyl)-4-nitrobenzyl alcohol monohydrochloride
1-(4-Nitrophenyl)-2-[(propan-2-yl)amino]ethan-1-ol--hydrogen chloride (1/1)
BENZENEMETHANOL, .ALPHA.-(((1-METHYLETHYL)AMINO)METHYL)-4-NITRO-, MONOHYDROCHLORIDE
Benzenemethanol, alpha-(((1-methylethyl)amino)methyl)-4-nitro-, monohydrochloride, (+-)-
Benzyl alcohol, alpha-((isopropylamino)methyl)-p-nitro-, monohydrochloride, (+-)-
BENZENEMETHANOL, .ALPHA.-(((1-METHYLETHYL)AMINO)METHYL)-4-NITRO-, MONOHYDROCHLORIDE, (+/-)-
BENZYL ALCOHOL, .ALPHA.-((ISOPROPYLAMINO)METHYL)-P-NITRO-, MONOHYDROCHLORIDE, (+/-)-