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Tetrahydroxybutylfuran

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Identification
Molecular formula
C5H10O4
CAS number
488-81-3
IUPAC name
2-(hydroxymethyl)tetrahydrofuran-3,4-diol
State
State

At room temperature, tetrahydroxybutylfuran is a solid that can readily dissolve in water due to its polar nature, attributed to the presence of multiple hydroxyl (OH) groups.

Melting point (Celsius)
105.00
Melting point (Kelvin)
378.00
Boiling point (Celsius)
284.00
Boiling point (Kelvin)
557.00
General information
Molecular weight
136.13g/mol
Molar mass
136.1330g/mol
Density
1.5730g/cm3
Appearence

Tetrahydroxybutylfuran is a crystalline solid with a white appearance. It is known to be hygroscopic, meaning it can absorb moisture from the environment. Its fine crystals give it a somewhat powdery texture.

Comment on solubility

Solubility of 2-(hydroxymethyl)tetrahydrofuran-3,4-diol

The solubility of 2-(hydroxymethyl)tetrahydrofuran-3,4-diol, with the molecular formula C5H10O4, can be described as largely dependent on its structural characteristics. Being a polyol, it contains several hydroxyl (-OH) groups that significantly influence its solubility properties.

Here are some key points regarding its solubility:

  • Highly Soluble in Water: Due to the presence of multiple hydroxyl groups, this compound is generally soluble in water, making it a valuable ingredient in various aqueous formulations.
  • Versatile Solvent Interaction: The hydrogen bonding capacity of the hydroxyl groups allows for favorable interactions with polar solvents, enhancing its solubility in polar organic solvents.
  • Lower Solubility in Non-Polar Solvents: Conversely, the presence of hydroxyl groups reduces solubility in non-polar solvents, which is a characteristic common in polar compounds.

It's essential to note that the solubility behavior might vary based on factors such as temperature and pH. The ability of this compound to dissolve effectively in polar environments underscores its potential applicability in various chemical and pharmaceutical contexts. As with many water-soluble compounds, environmental factors play a critical role in defining how and where they can be used.

Interesting facts

Interesting Facts about 2-(hydroxymethyl)tetrahydrofuran-3,4-diol

2-(hydroxymethyl)tetrahydrofuran-3,4-diol is a fascinating compound with significant implications in various fields of science and industry. Here are some intriguing points about this compound:

  • Structure and Functionality: This compound features a tetrahydrofuran ring, which is a versatile building block in organic chemistry. The presence of hydroxymethyl groups enhances its reactivity, making it a valuable intermediate in synthesis.
  • Role in Synthesis: Its structure allows it to serve as a precursor for the development of biologically active compounds, including pharmaceuticals and agrochemicals. The unique arrangement of hydroxyl groups can lead to interesting reactions, such as molecular transformations and polymerizations.
  • Potential in Green Chemistry: Due to its renewable nature and derived from biomass sources, 2-(hydroxymethyl)tetrahydrofuran-3,4-diol aligns with the principles of green chemistry. It can be utilized in the formulation of environmentally friendly products and materials.
  • Applications in Biotechnology: This compound has emerged as a candidate for various applications in biotechnology, including its use in drug delivery systems and as a stabilizing agent for protein formulations.
  • Structural Analogues: The study of 2-(hydroxymethyl)tetrahydrofuran-3,4-diol can also extend to its analogues, offering insights into structure-activity relationships (SAR) that are crucial for drug design and development.

In summary, 2-(hydroxymethyl)tetrahydrofuran-3,4-diol is not just another compound; it represents a crossroads of chemistry, biology, and sustainability. As we delve deeper into its properties and potential applications, we may unlock new avenues for innovation in drug discovery and material science.

Synonyms
1,4-anhydro-l-ribitol
51607-76-2
1-Deoxy-D-ribose
nt-pentose-ring
MFCD27923011
2-(hydroxymethyl)oxolane-3,4-diol
NSC126586
SCHEMBL1425304
AKOS032947997
NSC-126586
2-methylol-3,4-dihydroxytetrahydrofuran
SY055527