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Didanosine

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Identification
Molecular formula
C10H12N4O3S
CAS number
69655-05-6
IUPAC name
2-(hydroxymethyl)-5-(6-sulfanylpurin-9-yl)tetrahydrofuran-3,4-diol
State
State

Didanosine is typically a solid at room temperature. It is processed in the form of tablets or powders for pharmaceutical use.

Melting point (Celsius)
185.00
Melting point (Kelvin)
458.20
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
236.24g/mol
Molar mass
236.2410g/mol
Density
1.5000g/cm3
Appearence

Didanosine typically appears as a white or almost white crystalline powder. It is highly soluble in water and slightly soluble in ethanol.

Comment on solubility

Solubility of 2-(hydroxymethyl)-5-(6-sulfanylpurin-9-yl)tetrahydrofuran-3,4-diol

The solubility of the compound 2-(hydroxymethyl)-5-(6-sulfanylpurin-9-yl)tetrahydrofuran-3,4-diol (C10H12N4O3S) exhibits intriguing characteristics that merits examination. Here are some key points about its solubility:

  • Solvent Dependence: The solubility is highly influenced by the choice of solvent. The presence of hydroxyl (-OH) groups suggests that this compound may dissolve well in polar solvents such as water.
  • pH Sensitivity: The solubility may vary with pH. Compounds with amine and sulfanyl groups could engage in protonation reactions, altering their solubility profile.
  • Temperature Effects: An increase in temperature typically enhances solubility for many organic compounds. Thus, solubility measurements at different temperatures could yield valuable insights.
  • Hydrophilic vs. Hydrophobic: The balance between the hydrophilic characteristics from the hydroxymethyl and the hydrophobic interactions from the purinyl moiety suggests a potential for moderate solubility.

In summary, while the precise solubility parameters may require empirical determination, the factors above are critical in understanding how 2-(hydroxymethyl)-5-(6-sulfanylpurin-9-yl)tetrahydrofuran-3,4-diol interacts with various solvents. Exploring these aspects can reveal potential applications in pharmaceuticals and biochemistry.

Interesting facts

Interesting Facts about 2-(Hydroxymethyl)-5-(6-sulfanylpurin-9-yl)tetrahydrofuran-3,4-diol

This compound is particularly noteworthy due to its structural complexity and biological significance. Here are some intriguing aspects of this compound:

  • Biological Role: The compound is related to various biological activities, particularly in the realm of medicinal chemistry where it could play a role as a pharmaceutical agent.
  • Sulfur Incorporation: The presence of a sulfanyl group highlights the importance of sulfur in biological molecules, often contributing to the activity of various drugs.
  • Synthesis Challenges: The synthesis of this compound may require intricate multi-step procedures, showcasing the creativity and problem-solving skills of organic chemists.
  • Structural Features: Its unique tetrahydrofuran ring and hydroxymethyl substituents are crucial for its potential interactions with biological targets, making its structure a topic of study in both drug design and organic synthesis.

Moreover, this compound emphasizes the fascinating intersection of theoretical chemistry and practical applications in pharmacology. As researchers continue to uncover the potential benefits of such compounds, their study could lead to vital innovations in treating various diseases.

In summary, 2-(hydroxymethyl)-5-(6-sulfanylpurin-9-yl)tetrahydrofuran-3,4-diol embodies the challenges and rewards faced by chemists, as they delve into the multifaceted world of chemical compounds that inform our understanding of the biological landscape.