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7-Hydroxycoumarin

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Identification
Molecular formula
C9H6O3
CAS number
531-59-9
IUPAC name
2-hydroxychromen-7-one
State
State

At room temperature, 7-Hydroxycoumarin is in a solid-state. It is usually handled in powder or crystalline form for various laboratory and industrial applications. It has notable UV fluorescence, which can be observed under specific conditions.

Melting point (Celsius)
228.00
Melting point (Kelvin)
501.15
Boiling point (Celsius)
374.00
Boiling point (Kelvin)
647.15
General information
Molecular weight
178.15g/mol
Molar mass
178.1530g/mol
Density
1.3060g/cm3
Appearence

7-Hydroxycoumarin typically appears as a pale yellow or light cream crystalline solid. It can also sometimes appear in a white powder form. The compound is known for its fluorescent properties, which makes it widely used in biochemical applications.

Comment on solubility

Solubility of 2-hydroxychromen-7-one (C9H6O3)

The solubility of 2-hydroxychromen-7-one is an important characteristic that influences its behavior in various chemical environments. This compound, being a flavone derivative, generally exhibits certain solubility traits:

  • Polarity: 2-hydroxychromen-7-one contains both aromatic and hydroxyl functional groups, which affects its polarity. The hydroxyl group contributes to its ability to interact with polar solvents.
  • Solvent Compatibility: It is typically soluble in organic solvents such as ethanol, methanol, and acetone. In contrast, its solubility in water is limited.
  • Temperature Dependence: Like many organic compounds, solubility can vary with temperature, often increasing in warmer solvents.

In summary, the solubility of 2-hydroxychromen-7-one can be described as:

  1. More soluble in organic solvents
  2. Limited solubility in polar solvents like water
  3. Increased solubility can be observed with increased temperature

Understanding the solubility of 2-hydroxychromen-7-one is crucial for its application in various fields, including pharmaceuticals and natural product chemistry.

Interesting facts

Interesting Facts About 2-hydroxychromen-7-one

2-hydroxychromen-7-one, also known as coumarin, is a fascinating compound with a rich history and numerous applications across various fields. Here's what you should know about this remarkable molecule:

  • Cultural Significance: Coumarin is often associated with a sweet scent reminiscent of freshly cut grass, making it popular in the perfume industry.
  • Natural Occurrence: This compound can be found naturally in several plants, most notably in tonka beans and sweet clover, showcasing its role in the botanical world.
  • Biological Activity: 2-hydroxychromen-7-one exhibits a variety of biological activities, including anti-inflammatory, antioxidant, and even antimicrobial properties. This makes it a subject of interest in medicinal chemistry.
  • Reaction Versatility: The structure of this compound allows it to participate in numerous chemical reactions, including synthesis pathways leading to more complex molecules. Its versatility is highly regarded in synthetic organic chemistry.
  • Potential Applications: Beyond fragrances, 2-hydroxychromen-7-one has potential uses in pharmaceuticals, as it has been researched for its anticoagulant properties, which could lead to new blood-thinning medications.

Interestingly, researchers emphasize the importance of continuing studies on this compound, as its unique structure may hold the key to developing new therapeutic agents. As stated by one prominent chemist, "The exploration of coumarin derivatives could uncover groundbreaking applications that bridge nature and modern medicine."

Overall, 2-hydroxychromen-7-one stands as a testament to the intersection of chemistry, nature, and health, making it a compound of great interest in both academic and applied contexts.