Interesting facts
Interesting Facts about 2-Hydroxybenzamide
2-Hydroxybenzamide, also known as salicylamide, is a fascinating compound that has captured the attention of chemists due to its intriguing properties and applications. Here are some notable facts:
- Origin of the Name: The name "salicylamide" is derived from "salicylic acid," reflecting its structure, which shares a common functional element with this well-known compound.
- Medicinal Uses: This amide is often investigated for its potential in medicinal chemistry. It exhibits properties that can enhance the anti-inflammatory effects of other compounds.
- Biological Activity: Research has indicated that 2-hydroxybenzamide may possess antimicrobial properties, contributing to studies in pharmaceuticals aimed at developing new antibiotics.
- Role in Organic Synthesis: Salicylamide serves as an important intermediate in various organic synthesis processes, allowing chemists to create more complex molecules in a stepwise manner.
- Hydrogen Bonding: This compound features functional groups that can participate in **hydrogen bonding**, making it an essential tool for studying hydrogen bond interactions in biological systems.
As students delve into the realm of organic chemistry, they will find that 2-hydroxybenzamide encourages a deep understanding of:
- Functional group behavior
- Reactivity patterns in aromatic compounds
- Biological significance within pharmaceutical contexts
In summary, 2-hydroxybenzamide is much more than just a simple amide; it represents the intersection of organic chemistry and medicinal applications, making it a compound of *great interest* for both researchers and students alike.
Synonyms
salicylamide
2-Hydroxybenzamide
65-45-2
o-Hydroxybenzamide
2-Carbamoylphenol
Salicylic acid amide
Benzamide, 2-hydroxy-
Urtosal
2-Carboxamidophenol
Algiamida
Amidosal
Dolomide
Dropsprin
Eggosalil
Flarpirina
Liquiprin
Morsarinas
Panithal
Raspberin
Salamide
Saliamid
Saliamin
Salizell
Serramida
Algamon
Allevin
Anamid
Andasol
Novecyl
Oramid
Salicim
Salipur
Salrin
Salymid
Acket
Afko-Sal
Amid-Sal
Salicilamida
Benzamide, o-hydroxy-
Salicilamide
Salicylamidum
Amid kyseliny salicylove
MFCD00007978
NSC 3115
OHB
Salicylamid
CCRIS 6045
HSDB 227
Cidal
Samid
H.P. 34
SR 4326
Benzoic acid, 2-hydroxy-, amide
UNII-EM8BM710ZC
NSC-3115
EINECS 200-609-3
EM8BM710ZC
2-Hydroxy-benzamide
BRN 0742439
DTXSID3021726
CHEBI:32114
AI3-03454
CHEMBL27577
MLS000069486
DTXCID501726
EC 200-609-3
4-10-00-00169 (Beilstein Handbook Reference)
NCGC00091414-02
SMR000046394
Salicylamide 100 microg/mL in Acetonitrile
SALICYLAMIDE (MART.)
SALICYLAMIDE [MART.]
Salizell (VAN)
Benesal (VAN)
SALICYLAMIDE (USP-RS)
SALICYLAMIDE [USP-RS]
Salicilamide [DCIT]
Salicilamide [Italian]
SALICYLAMIDE (USP MONOGRAPH)
SALICYLAMIDE [USP MONOGRAPH]
Salicylamidum [INN-Latin]
CAS-65-45-2
Salicilamida [INN-Spanish]
Amid kyseliny salicylove [Czech]
hydroxy benzamide
Saliclamide,(S)
dihydroxybenzalamine
Salicylamide [USP:INN:BAN:JAN]
Salicylamide (TN)
Salicylamide, 99%
Spectrum_000946
Salicylamide (Standard)
Opera_ID_1684
Spectrum2_001312
Spectrum3_000564
Spectrum4_000499
Spectrum5_001032
SALICYLAMIDE [MI]
WLN: ZVR BQ
SALICYLAMIDE [INN]
SALICYLAMIDE [JAN]
SALICYLAMIDE [HSDB]
NCIOpen2_001127
SALICYLAMIDE [VANDF]
Oprea1_069894
SCHEMBL21646
BSPBio_001948
KBioGR_001017
KBioSS_001426
DivK1c_000858
SALICYLAMIDE [WHO-DD]
SPECTRUM1500532
Salicylamide (JAN/USP/INN)
SPBio_001403
benzenecarboxamide, 2-hydroxy-
HMS502K20
HY-B0811R
KBio1_000858
KBio2_001426
KBio2_003994
KBio2_006562
KBio3_001448
N02BA05
NSC3115
NINDS_000858
HMS1920P14
HMS2092G15
HMS2232E07
Pharmakon1600-01500532
component of Tolagesic (Salt/Mix)
HY-B0811
Tox21_111129
Tox21_201944
Tox21_302801
BBL016007
BDBM50056900
CCG-39250
NSC757318
s6404
STK301812
AKOS000120983
Tox21_111129_1
CS-7630
DB08797
FS27782
NSC-757318
IDI1_000858
NCGC00091414-01
NCGC00091414-03
NCGC00091414-04
NCGC00091414-05
NCGC00091414-07
NCGC00256376-01
NCGC00259493-01
287492-04-0
DS-16216
Salicylamide, puriss., >=99.0% (T)
SY009157
SBI-0051509.P003
DB-269424
EU-0000058
NS00006293
S0006
EN300-18542
SALICYLAMIDE, 2-HYDROXYBENZOICACIDAMIDE
D01811
F85552
AB00052089_12
AH-034/32461056
SR-01000721923
BENZOIC ACID,2-HYDROXY,AMIDE SALICYLAMIDE
Q2496906
SR-01000721923-2
BRD-K81130846-001-02-6
BRD-K81130846-001-12-5
BRD-K81130846-001-17-4
Z68590124
2-Hydroxy-benzamide;2-Carbamoylphenol;2-Carboxamidophenol
2,4-CYCLOHEXADIEN-1-ONE, 6-(AMINOHYDROXYMETHYLENE)-
Salicylamide, United States Pharmacopeia (USP) Reference Standard
InChI=1/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10
Salicylamide, Pharmaceutical Secondary Standard; Certified Reference Material
200-609-3
Solubility of 2-Hydroxybenzamide (C7H7NO2)
2-Hydroxybenzamide, also known as salicylamide, exhibits interesting solubility characteristics that are influenced by its functional groups. Here are some important points regarding its solubility:
Overall, 2-hydroxybenzamide's solubility properties highlight the crucial role of intermolecular interactions, such as hydrogen bonding, in determining how and where this compound can be effectively dissolved.