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Glycolaldehyde

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Identification
Molecular formula
C2H4O2
CAS number
141-46-8
IUPAC name
2-hydroxyacetaldehyde
State
State
At room temperature, glycolaldehyde exists as a solid, which means it can readily sublimate or dissolve into water, demonstrating a strong affinity for water absorption.
Melting point (Celsius)
50.00
Melting point (Kelvin)
323.00
Boiling point (Celsius)
144.00
Boiling point (Kelvin)
417.00
General information
Molecular weight
60.05g/mol
Molar mass
60.0520g/mol
Density
1.2650g/cm3
Appearence

Glycolaldehyde appears as a colorless solid with a pleasant odor. It is mainly found as dimeric units due to its tendency to polymerize, and in solution, it can easily form hydrates.

Comment on solubility

Solubility of 2-hydroxyacetaldehyde (C2H4O2)

2-hydroxyacetaldehyde, also known as glycolaldehyde, exhibits notable solubility characteristics that make it a significant compound in various chemical applications. Here’s a detailed overview of its solubility:

  • Solvent Interaction: 2-hydroxyacetaldehyde is highly soluble in polar solvents, particularly water, due to its ability to form hydrogen bonds.
  • Concentration Influence: Its solubility increases with concentration, showing a positive correlation between temperature and solubility. This means that as temperature rises, the solubility in water enhances, allowing for greater dilution and use in reactions.
  • Comparison with Other Compounds: Compared to other aldehydes, 2-hydroxyacetaldehyde stands out for its superior solubility, which can be attributed to the presence of the hydroxyl group that enhances its affinity for water.

Due to these properties, 2-hydroxyacetaldehyde is often utilized in biochemical processes and as a versatile intermediate in synthetic organic chemistry. Its solubility profile makes it an essential compound for studies in various fields, including medicine and environmental science.

In summary, understanding the solubility of 2-hydroxyacetaldehyde is crucial for its practical applications, wherein its behavior in different solvents can significantly influence chemical reactions and formulations.

Interesting facts

Interesting Facts about 2-Hydroxyacetaldehyde

2-Hydroxyacetaldehyde, commonly referred to as glycolaldehyde, is a fascinating compound with a myriad of interesting properties and applications in both organic chemistry and biochemistry. Below are some notable facts about this intriguing molecule:

  • Simple Structure, Complex Behavior: Despite its relatively simple structure, 2-hydroxyacetaldehyde plays a critical role in various chemical pathways, especially in synthetic organic chemistry.
  • Natural Occurrence: This compound is not just a laboratory artifact; it occurs naturally in living organisms and is considered a building block in the processes of glycolysis and the metabolism of carbohydrates.
  • Interstellar Chemistry: Surprisingly, 2-hydroxyacetaldehyde has been detected in space, specifically in the interstellar medium, indicating its potential significance in the origins of life beyond Earth.
  • Aldehyde with a Twist: As an aldehyde with a hydroxyl group, it exhibits unique reactivity, allowing it to participate in various reactions such as polymerization and condensation, facilitating the synthesis of larger organic molecules.
  • Flavor and Fragrance Properties: 2-Hydroxyacetaldehyde possesses a pleasant smell and is therefore utilized in the flavoring and fragrance industries, adding aromatic qualities to products.

In summary, 2-hydroxyacetaldehyde is a prime example of how a small and seemingly simple molecule can have significant implications in both the natural world and human applications. Its roles in synthetic chemistry, astrobiology, and industry demonstrate the compound's versatility and importance in a wide array of fields.

Synonyms
glycolaldehyde
2-Hydroxyacetaldehyde
141-46-8
hydroxyacetaldehyde
Glycolic aldehyde
Diose
Acetaldehyde, hydroxy-
GLYCOALDEHYDE
Glycollaldehyde
Methylol formaldehyde
Monomethylolformaldehyde
2-hydroxyethanal
Methylolformaldehyde
2-OH-acetaldehyde
Hydroxyethanal
2-Oxoethanol
NSC 67935
CCRIS 2613
Acetaldehyde, hydroxy- (9CI)
BRN 0506029
2-oxidanylethanal
UNII-W0A0XPU08U
EINECS 205-484-9
W0A0XPU08U
HOCH2CHO
GLYCOLLIC ALDEHYDE
NSC-67935
GLYCOLALDEHYDE [MI]
DTXSID4074693
CHEBI:17071
Acetaldehyde, hydroxy-(9CI)
glycol aldehyde
2Hydroxyethanal
Hydroxyacetoaldehyde
hydroxy-acetaldehyde
DW3
Acetaldehyde, hydroxy
Glycolaldehyde (8CI)
bmse000258
Acetaldehyde, hydroxy (9CI)
CHEMBL3884509
DTXCID4034570
NSC67935
AKOS010078724
NS00021010
EN300-91724
C00266
A902395
Q899877