Skip to main content

Salicylanilide

ADVERTISEMENT
Identification
Molecular formula
C13H11NO3
CAS number
87-17-2
IUPAC name
2-hydroxy-N-(4-hydroxyphenyl)benzamide
State
State

At room temperature, Salicylanilide is a solid. It is not very soluble in water but dissolves in organic solvents such as ethanol and dimethyl sulfoxide (DMSO).

Melting point (Celsius)
213.00
Melting point (Kelvin)
486.15
Boiling point (Celsius)
422.50
Boiling point (Kelvin)
695.70
General information
Molecular weight
213.13g/mol
Molar mass
213.2140g/mol
Density
1.2150g/cm3
Appearence

Salicylanilide typically appears as a white to off-white crystalline powder with no distinct odor. It is relatively stable under ordinary conditions and is not known to decompose readily.

Comment on solubility

Solubility of 2-hydroxy-N-(4-hydroxyphenyl)benzamide

2-hydroxy-N-(4-hydroxyphenyl)benzamide (C13H11NO3) exhibits interesting solubility characteristics that are influenced by its molecular structure and functional groups. Understanding the solubility of this compound is essential for various applications, including pharmaceuticals and chemical synthesis.

Key points regarding its solubility include:

  • Polar Nature: The presence of hydroxyl (-OH) groups in the structure enhances polarity, which can increase solubility in polar solvents like water.
  • Hydrogen Bonding: The ability of 2-hydroxy-N-(4-hydroxyphenyl)benzamide to form hydrogen bonds with solvents further boosts its solubility.
  • Solvent Dependence: It is likely to have variable solubility in organic solvents; for example, it may dissolve well in ethanol or methanol but not in non-polar solvents like hexane.
  • Potential Applications: High solubility in appropriate solvents could facilitate its use in drug formulation or chemical reactions.

In summary, while the solubility of 2-hydroxy-N-(4-hydroxyphenyl)benzamide is generally favorable in polar solvents, it is crucial to consider specific conditions and solvent choices for practical applications. Understanding the solubility behavior of this compound opens doors to its effective utilization in various scientific fields.

Interesting facts

Interesting Facts About 2-Hydroxy-N-(4-hydroxyphenyl)benzamide

2-Hydroxy-N-(4-hydroxyphenyl)benzamide, also known as a derivative of benzamide, has gained considerable interest in the field of medicinal chemistry. This compound presents a fascinating structure that encourages a range of biological activities, making it a subject of interest for researchers.

  • Structure and Function: The unique arrangement of hydroxyl groups attached to the aromatic rings enhances the compound's ability to interact with various biological targets, potentially increasing its effectiveness as a pharmaceutical agent.
  • Antioxidant Properties: Many studies have highlighted the antioxidant potential of similar compounds, suggesting that 2-hydroxy-N-(4-hydroxyphenyl)benzamide could assist in combating oxidative stress in cells.
  • Role in Drug Development: This compound serves as a key structural template for the design of new drugs. Its versatility allows modifications that can lead to improved therapeutic profiles, emphasizing its role in innovation within drug development.
  • Potential Applications: Research indicates potential uses in treating conditions like cancer and inflammation. The specific substitution pattern of functional groups opens pathways for targeted therapy.

As a scientist or a student, you might appreciate how each structural component provides insights into its reactivity and interactions with biological targets. The exploration of compounds like 2-hydroxy-N-(4-hydroxyphenyl)benzamide epitomizes the intricate relationship between chemistry and biology, paving the way for advances in therapeutic solutions.

In the words of a noted chemist, "The beauty of chemistry is in its ability to transform seemingly simple structures into complex solutions." This compound exemplifies that beauty and potential.

Synonyms
osalmid
526-18-1
2-Hydroxy-N-(4-hydroxyphenyl)benzamide
Oxaphenamide
Osalmide
4'-Hydroxysalicylanilide
Oxaphenamid
Salmidochol
Bilene
Dribazil
Oksafenamid
Saryuurin
2-Hydroxy-N-(4-hydroxyphenyl)-Benzamide
Auxobil
Enidran
Driol
Driol-labaz
Bilocol
Osalmida
p'-Hydroxysalicylanilide
Oxaphenamidum
Hydroxyphenyl salicylamide
PHPS
p-Hydroxyphenylsalicylamide
N'-Salicyloyl-p-aminophenol
Benzamide, 2-hydroxy-N-(4-hydroxyphenyl)-
N-(p-Hydroxyphenyl)salicylamide
N-(4-Hydroxyphenyl)salicylamide
Osalmidum
Osalmid [INN:JAN]
Osalmide [INN-French]
Osalmidum [INN-Latin]
Osalmida [INN-Spanish]
SALICYLANILIDE, 4'-HYDROXY-
NSC 93960
NSC-93960
L 1718
L-1718
EINECS 208-385-9
BRN 2941480
DTXSID0042244
OSALMID [INN]
OSALMID [JAN]
OSALMID [MI]
OSALMID [MART.]
OSALMID [WHO-DD]
Oksafenamide
89741L759Z
DTXCID8022244
3-13-00-01137 (Beilstein Handbook Reference)
Oxaphenamide;4'-Hydroxysalicylanilide
NCGC00160580-01
Osalmide (INN-French)
Osalmidum (INN-Latin)
Osalmida (INN-Spanish)
OSALMID (MART.)
2-Hydroxy-N-(4-Hydroxy Phenyl)Benzamide
Fumispore
Jestmin
Kanochol
Yoshicol
Li Dan Feng
UNII-89741L759Z
N-salicoylaminophenol
MFCD00020026
Osalmid (JAN/INN)
WLN: QR BVMR DQ
MLS006011715
SCHEMBL220088
CHEMBL389507
CHEBI:31938
N-(p-Hydroxyphenyl)salicylanilide
HY-B2116
NSC93960
Tox21_111914
BDBM50618907
s3641
AKOS008980445
AC-1737
CCG-266789
CS-6242
FH36692
KS-5271
NCGC00160580-02
CAS-526-18-1
SMR004703438
WR 17456
2-Hydroxy-N-(4-hydroxyphenyl)benzamide #
NS00001303
D01579
F14930
SBI-0654011.0001
EN300-7359305
Benzamide, 2-hydroxy-N-(4-hydroxyphenyl)-(9CI)
SR-01000945010
SR-01000945010-1
BRD-K39693230-001-01-2
Q27270017
Z69118312
208-385-9