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Oxaloglutaric acid

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Identification
Molecular formula
C5H6O5
CAS number
362-66-3
IUPAC name
2-hydroxy-4-oxo-pentanedioic acid
State
State
Solid at room temperature, appearing as a white crystalline powder.
Melting point (Celsius)
168.00
Melting point (Kelvin)
441.15
Boiling point (Celsius)
340.00
Boiling point (Kelvin)
613.15
General information
Molecular weight
146.11g/mol
Molar mass
148.1000g/mol
Density
1.8134g/cm3
Appearence

Oxaloglutaric acid typically appears as a white crystalline powder. It may come in the form of granules or fine crystals, depending on the method of preparation and purification. In its pure state, it is odorless and has a slightly acidic taste due to its carboxylic acid groups. The compound's crystalline form makes it relatively easy to handle and quantify in laboratory settings.

Comment on solubility

Solubility of 2-Hydroxy-4-oxo-pentanedioic Acid (C5H6O5)

2-Hydroxy-4-oxo-pentanedioic acid, commonly known as α-ketoglutaric acid, exhibits interesting solubility characteristics due to its functional groups. The solubility of this compound is notably influenced by the presence of both acidic and hydroxyl group functionalities, which facilitate hydrogen bonding with water molecules.

Key Points on Solubility:

  • Highly Soluble in Water: This compound is water-soluble, allowing it to readily dissolve when mixed with water, thanks to its polar nature.
  • pH Dependency: Its solubility may vary with pH, as the acidic groups can donate protons or become neutralized, altering their interaction with water.
  • Temperature Effects: Generally, solubility tends to increase with temperature; therefore, higher temperatures may enhance the dissolution rate of 2-hydroxy-4-oxo-pentanedioic acid.

As a result, when considering the applications of 2-hydroxy-4-oxo-pentanedioic acid in chemical processes or biological systems, its solubility properties become a vital factor to ensure effective utilization.

Interesting facts

Interesting Facts about 2-Hydroxy-4-Oxo-Pentanedioic Acid

2-Hydroxy-4-oxo-pentanedioic acid, commonly known as malic acid, is a fascinating organic compound that plays a significant role in various biochemical processes. Here are some intriguing aspects of this compound:

  • Biosynthesis: Malic acid is a key intermediate in the Citric Acid Cycle, also known as the Krebs cycle, which is essential for cellular respiration and energy production in living organisms.
  • Natural Occurrence: This compound is naturally found in many fruits, especially apples. Its presence contributes to the tart flavor of these fruits, and it has been widely used in the food industry as a natural flavor enhancer.
  • Health Benefits: Studies have indicated that malic acid may aid in energy production and reduce muscle fatigue. It has also been explored for its potential to improve skin health and as a chelating agent for detoxification.
  • Industrial Applications: Beyond its biological significance, malic acid is utilized in the cosmetic and pharmaceutical industries. It’s often found in skin care products due to its exfoliating properties and is also used in the formulation of various medications.
  • Environmental Impact: As a biodegradable compound, malic acid poses minimal environmental risk compared to synthetic acids, making it a preferred choice in eco-friendly formulations.

In summary, 2-hydroxy-4-oxo-pentanedioic acid is not only crucial for metabolic processes but also serves important roles across multiple industries, demonstrating the interconnectedness of chemistry, biology, and even culinary applications. Its versatile nature makes it a valuable subject of study for scientists and a compound worthy of recognition in the world of chemistry.

Synonyms
2-Hydroxy-4-oxopentanedioic acid
1187-99-1
4-Hydroxy-2-oxoglutaric acid
Pentanedioic acid,2-hydroxy-4-oxo-
2-keto-4-hydroxyglutarate
DL-4-Hydroxy-2-ketoglutarate Dilithium Salt
DL-4-HYDROXY-2-KETOGLUTARATE
Pentanedioic acid, 2-hydroxy-4-oxo-
SCHEMBL126063
4-hydroxy-2-ketoglutaric acid
CHEBI:30923
DTXSID60862580
WXSKVKPSMAHCSG-UHFFFAOYSA-N
(+/-)-2-hydroxy-4-oxopentanedioate
AKOS030239798
FH24198
(+/-)-2-hydroxy-4-oxopentanedioic acid
NS00126510
C01127
Q27104173