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Pyruvic acid

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Identification
Molecular formula
C3H4O3
CAS number
127-17-3
IUPAC name
2-hydroxy-3-oxo-propanoic acid
State
State

Pyruvic acid is a liquid at room temperature with a tendency to form crystals upon cooling.

Melting point (Celsius)
13.80
Melting point (Kelvin)
286.95
Boiling point (Celsius)
165.00
Boiling point (Kelvin)
438.15
General information
Molecular weight
88.06g/mol
Molar mass
88.0620g/mol
Density
1.2506g/cm3
Appearence

Pyruvic acid is a colorless liquid with a faintly sweet, vinegar-like odor. It is also hygroscopic and absorbs moisture from the air.

Comment on solubility

Solubility of 2-hydroxy-3-oxo-propanoic acid (C3H4O3)

2-hydroxy-3-oxo-propanoic acid, commonly known as **pyruvic acid**, exhibits distinct solubility characteristics due to its structure and functional groups. This compound is notable for its:

  • High solubility in water: Pyruvic acid is significantly soluble in water, owing to the presence of both hydroxyl (-OH) and carbonyl (C=O) functional groups. These groups form hydrogen bonds with water molecules, enhancing its solubility.
  • Solubility in organic solvents: In addition to water, pyruvic acid is soluble in various organic solvents, such as ethanol and acetone, further broadening its use in different chemical applications.
  • pH-dependent solubility: The solubility of 2-hydroxy-3-oxo-propanoic acid can be influenced by the pH of the solution. At lower pH levels, the acid is more prevalent in its protonated form, which is soluble, while increased pH might lead to different behavior.

Overall, the **substantial solubility** of pyruvic acid makes it a valuable compound in various biochemical and pharmaceutical contexts. As noted in the literature, "its ability to dissolve in both aqueous and organic phases allows for versatile applications in synthesis and research." This feature highlights its significance as a key intermediate in metabolic pathways as well.

Interesting facts

Interesting Facts about 2-Hydroxy-3-oxo-propanoic Acid

2-Hydroxy-3-oxo-propanoic acid, also known as pyruvic acid, is a fascinating compound in the field of biochemistry and organic chemistry. Here are some insights into this important molecule:

  • Key Intermediate: Pyruvic acid serves as a crucial intermediate in several metabolic processes, including glycolysis, which is vital for cellular respiration and energy production.
  • Metabolic Applications: It is not only an essential compound in energy metabolism but also plays a role in the synthesis of various amino acids and neurotransmitters.
  • Research and Medicine: Owing to its central role in metabolism, pyruvic acid has been studied for its potential therapeutic applications, including its effects on exercise performance and weight loss.
  • Flexibility in Reactions: In addition to being a precursor for many biochemical substances, it can undergo various chemical reactions, such as esterification and decarboxylation, making it a versatile building block in organic synthesis.
  • Flavor and Aroma: Pyruvic acid is also implicated in the flavor profile of some foods and beverages, contributing to the richness of flavors in fermented products and certain fruits.

As a scientist or a student, studying compounds like 2-hydroxy-3-oxo-propanoic acid can provide deeper insights into metabolic pathways, paving the way for advances in biochemical research and potential medical therapies. Its multifaceted roles illustrate the interconnectedness of organic chemistry and biology in understanding life processes.

Synonyms
2-hydroxy-3-oxopropanoic acid
tartronate semialdehyde
hydroxymalonaldehydic acid
2480-77-5
tartronic semialdehyde
2-hydroxy-3-oxopropanoate
Propanoic acid, 2-hydroxy-3-oxo-
tartronate-S-ald
CHEBI:16992
2-hydroxy-3-oxopropanoate anion
2-hydroxy-3-oxopropanoate(1-)
CHEBI:57978
DTXSID90947713
Tartronyl semialdehyde
Formyl(hydroxyl)acetic acid
Triadimenol metabolite P05
SCHEMBL284876
DTXCID501375970
AKOS006381250
NS00067816
C01146
Q15732146