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Phosphatidylcholine

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Identification
Molecular formula
C42H80NO8P
CAS number
8002-43-5
IUPAC name
2-[hydroxy-[3-hydroxy-2-(octadecanoylamino)octadec-4-enoxy]phosphoryl]oxyethyl-trimethyl-ammonium
State
State

At room temperature, phosphatidylcholine is typically found in a solid state. In various natural and industrial applications, it may be processed or combined into liquid formulations as part of lecithin or lipid preparations.

Melting point (Celsius)
257.00
Melting point (Kelvin)
530.15
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.15
General information
Molecular weight
760.08g/mol
Molar mass
760.0760g/mol
Density
1.0300g/cm3
Appearence

Phosphatidylcholine typically appears as a white, waxy solid or powder at room temperature. It is a type of phospholipid that is commonly found in lecithin. It often has a characteristic waxy texture and may have a slightly fatty odor.

Comment on solubility

Solubility Overview

The compound 2-[hydroxy-[3-hydroxy-2-(octadecanoylamino)octadec-4-enoxy]phosphoryl]oxyethyl-trimethyl-ammonium (C42H80NO8P) displays unique solubility characteristics due to its complex structure. It belongs to a class of phosphoryl-containing surfactants which generally introduce amphiphilic properties in molecules, dictating how they interact with solvents.

Key Solubility Insights

  • Hydrophobic Tail: The octadecanoyl group and the extensive hydrocarbon chains contribute to the compound's hydrophobic nature, typically making it less soluble in water.
  • Polar Groups: The presence of multiple hydroxyl (-OH) and ammonium (-N(CH3)3) groups indicates that the molecule may exhibit some solubility in polar solvents, enhancing its interaction with water. This could lead to effective dispersion in aqueous media.
  • Structured Solubility: Depending on concentration, temperature, and pH, this compound may be more soluble in mixed solvents or in the presence of other stabilizing agents. “Like dissolves like” principle applies here, suggesting its enhanced solubility in mixed amphiphilic environments.

Overall, the solubility behavior of this compound is influenced by its intricate balance between hydrophilic and hydrophobic components, making it an interesting subject of study for its potential applications in various fields, including pharmaceuticals and material science.

Interesting facts

Interesting Facts About 2-[hydroxy-[3-hydroxy-2-(octadecanoylamino)octadec-4-enoxy]phosphoryl]oxyethyl-trimethyl-ammonium

This compound, often referred to as a phospholipid or phospholipid-like molecule, demonstrates the intriguing intersection of biochemistry and materials science. Here are several captivating aspects of this compound that highlight its significance in various scientific fields:

  • Biological Importance: Phospholipids play a crucial role in forming cellular membranes, acting as bilayers that protect and organize cellular components. The presence of long-chain fatty acids, such as octadecanoyl, suggests potential applications in lipid bilayer studies.
  • Functional Versatility: This molecule possesses both hydrophilic and hydrophobic segments, allowing it to interact with different environments. Such amphiphilic characteristics make it a valuable substance in drug delivery systems, where it can encapsulate hydrophobic drugs while remaining soluble in aqueous solutions.
  • Potential Applications: Beyond drug delivery, the unique chemical structure implies potential uses in foams, emulsions, and coatings. In cosmetics, for example, compounds similar to this one might be utilized for their moisturizing properties and ability to form stable emulsions.
  • Research Utility: This compound can serve as a model for studying membrane dynamics and interactions in a laboratory setting. Researchers can use it to examine how lipids interact within biological membranes, impacting processes like signal transduction and membrane fusion.
  • Quotes from Researchers: As noted by many in the field, “Phospholipids are not just structural components; they are dynamic players in cell signaling and membrane integrity.” This emphasizes the compound's significance beyond its mere composition.

In conclusion, 2-[hydroxy-[3-hydroxy-2-(octadecanoylamino)octadec-4-enoxy]phosphoryl]oxyethyl-trimethyl-ammonium is more than just a chemical entity; it embodies a gateway to advancements in pharmaceuticals, biotechnology, and materials science. Understanding its properties and potential applications can lead to breakthroughs in numerous scientific disciplines.