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Tolperisone

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Identification
Molecular formula
C12H17NO2
CAS number
1254-73-5
IUPAC name
(2-hydroxy-2-phenyl-butyl) carbamate
State
State

At room temperature, Tolperisone is generally in a solid crystalline form.

Melting point (Celsius)
64.00
Melting point (Kelvin)
337.15
Boiling point (Celsius)
383.20
Boiling point (Kelvin)
656.35
General information
Molecular weight
225.28g/mol
Molar mass
225.2840g/mol
Density
1.2350g/cm3
Appearence

The compound typically presents as a white to off-white crystalline powder.

Comment on solubility

Solubility of (2-hydroxy-2-phenyl-butyl) carbamate

The solubility of (2-hydroxy-2-phenyl-butyl) carbamate, with the chemical formula C12H17NO2, exhibits several interesting characteristics:

  • Solvent Dependence: The solubility of this compound can vary significantly depending on the solvent used. Generally, it is more soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO).
  • Hydrophilicity vs. Hydrophobicity: The presence of the hydroxyl group (-OH) imparts some degree of hydrophilicity, potentially enhancing solubility in polar solvents, while the phenyl group contributes hydrophobic characteristics.
  • Temperature Influence: Solubility could also be influenced by temperature; typically, increasing temperature may increase solubility for many compounds.
  • pH Sensitivity: In certain conditions, the solubility may be affected by the pH of the solution, especially in relation to the ionization of the carbamate functional group.

In practice, understanding the solubility profile can facilitate its application in various chemical processes and formulations. As a rule of thumb, when working with (2-hydroxy-2-phenyl-butyl) carbamate, consider experimenting with different solvents and conditions to optimize its solubility.

Interesting facts

Interesting Facts About (2-hydroxy-2-phenyl-butyl) carbamate

(2-hydroxy-2-phenyl-butyl) carbamate is a fascinating compound within the realm of organic chemistry, particularly noted for its various applications and properties. Here are some intriguing insights into this molecule:

  • Functionality: This compound features both an alcohol and a carbamate group, making it a useful building block in organic synthesis. The presence of these functional groups allows for diverse reactivity, which scientists can exploit in the development of more complex molecules.
  • Pharmaceutical Relevance: Compounds similar to (2-hydroxy-2-phenyl-butyl) carbamate have been studied for their potential applications in the pharmaceutical industry, including their roles as intermediates in drug synthesis.
  • Synthesis Routes: The synthesis of this carbamate can involve various strategies, such as the reaction of phenylbutanol with isocyanates, showcasing the compound's versatility and serving as an excellent laboratory exercise for students learning about organic synthesis techniques.
  • Environmental Considerations: As with many carbamates, studying the environmental impact and degradation pathways of (2-hydroxy-2-phenyl-butyl) carbamate is essential due to potential concerns regarding toxicity and persistence in ecosystems.
  • Chiral Significance: This compound may exist in chiral forms, which emphasizes the importance of stereochemistry in organic compounds. Understanding chirality is crucial for students as it significantly influences the behavior of molecules in biological systems.

In conclusion, (2-hydroxy-2-phenyl-butyl) carbamate not only serves as a noteworthy entity in synthetic organic chemistry but also opens avenues for exploration in pharmaceutical applications, environmental science, and stereochemistry. As students and researchers dive into its study, they will uncover the intricate relationships between molecular structure and function.

Synonyms
Oxyfenamate
Hydroxyphenamate
50-19-1
Listica
Oxyphenamate
Hidroxifenamato
Phenylbutamate
Tensifen
Oxifenamatum
2-Hydroxy-2-phenylbutyl carbamate
Oxifenamate
AL-0361
Hydroxyphenamate [USAN]
Oxifenamato
Oxyfenamatum
1,2-BUTANEDIOL, 2-PHENYL-, 1-CARBAMATE
2-Phenyl-1,2-butanediol 1-carbamate
NSC-108034
P-301
Oxyfenamatum [INN-Latin]
Oxifenamato [INN-Spanish]
Oxyfenamate [INN]
P 301
EINECS 200-017-5
(2-hydroxy-2-phenylbutyl) carbamate
NSC 108034
Oxyfenamate (INN)
AL 0361
BRN 2213242
Oxyphenamate;P 301
UNII-MD0414799X
Hydroxyphenamate (USAN)
NSC108034
MD0414799X
HYDROXYPHENAMATE [MI]
OXYFENAMATE [WHO-DD]
Carbamic acid, .beta.-ethyl-.beta.-hydroxyphenethyl ester
.beta.-Ethyl-.beta.-hydroxyphenethyl carbamate
DTXSID40861571
Oxyfenamatum (INN-Latin)
Oxifenamato (INN-Spanish)
beta-Ethyl-beta-hydroxyphenethyl carbamate
beta-Ethyl-beta-hydroxyphenethyl carbamic acid ester
Carbamic acid, beta-ethyl-beta-hydroxyphenethyl ester
WLN: ZVO1XQ2&R
SCHEMBL546919
1, 2-phenyl-, 1-carbamate
CHEMBL2107215
DTXCID80810487
CHEBI:134877
(2-hydroxy-2-phenyl-butyl) carbamate
AKOS040742355
CS-6618
DA-66418
HY-101754
NS00041196
D04476
Q27283901
.beta.-Ethyl-.beta.-hydroxyphenethyl carbamic acid ester