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Yohimbine

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Identification
Molecular formula
C21H26N2O3
CAS number
146-48-5
IUPAC name
(2-hydroxy-1-methyl-propyl) 4-isopropyl-7-methyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-carboxylate
State
State

Yohimbine is typically solid at room temperature.

Melting point (Celsius)
237.00
Melting point (Kelvin)
510.00
Boiling point (Celsius)
545.00
Boiling point (Kelvin)
818.00
General information
Molecular weight
354.47g/mol
Molar mass
354.4730g/mol
Density
1.2500g/cm3
Appearence

Yohimbine appears as white crystalline powder.

Comment on solubility

Solubility Insights for (2-hydroxy-1-methyl-propyl) 4-isopropyl-7-methyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-carboxylate

The solubility of (2-hydroxy-1-methyl-propyl) 4-isopropyl-7-methyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-carboxylate, with the chemical formula C21H26N2O3, can be influenced by various physicochemical properties. Understanding solubility is crucial for applications in pharmaceuticals, where it impacts bioavailability and efficacy. Here are some key points to consider:

  • Polarity: The presence of functional groups, such as hydroxyl and carboxyl, suggests that this compound may exhibit varying solubility in different solvents.
  • Solvent Interaction: It may dissolve well in polar solvents like water or methanol due to its hydroxyl group, but less so in non-polar solvents.
  • pH Effect: The solubility could be affected by the pH of the solution, especially due to the potential ionization of the carboxylic acid group.
  • Temperature Influence: Typically, an increase in temperature can enhance solubility, which may be applicable here as well.

Historically, compounds of similar structures have shown variable solubility profiles, often detailed in solubility studies for a comprehensive understanding. Researchers frequently investigate these parameters to find optimal conditions for application.

In conclusion, while specific solubility data for this compound may not be readily available in literature, it is essential to explore the solvent's nature, temperature, and pH, which can all significantly affect solubility outcomes.

Interesting facts

Exploring (2-hydroxy-1-methyl-propyl) 4-isopropyl-7-methyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-carboxylate

This fascinating compound belongs to the indole and quinoline families of organic compounds, renowned for their diverse biological activities. As a chemical scientist, I've found the structure and properties of this particular molecule to be quite captivating. Here are some intriguing insights:

  • Structural Complexity: This compound exhibits a complex structure that contains multiple rings, contributing to its unique properties. The indole and quinoline moieties are known for their roles in various pharmacological activities.
  • Potential Pharmacological Applications: Compounds with similar scaffolds have been investigated for their potential in developing medicines. Research indicates that they may possess anticancer, antimicrobial, and anti-inflammatory properties, making them of significant interest in medicinal chemistry.
  • Chirality and Its Implications: The presence of hydroxyl and methyl groups adds chirality to the molecule, which can greatly influence its biological activity. **Chirality** refers to the geometric property of a compound having non-superimposable mirror images, which is critical in drug design as different enantiomers can exhibit vastly different biological effects.
  • Research Opportunities: The intricacies of this molecule offer ample opportunities for research, particularly in fields like drug development and organic synthesis. Studying its synthesis and reactivity can yield insights into how structural modifications affect biological activity.
  • Environmentally Relevant: Beyond its medicinal applications, such compounds may also be explored for their environmental impact or utility, particularly in the development of sustainable chemical processes.

As we continue to unravel the mysteries surrounding such complex structures, the implications for future research and development in various domains remain incredibly promising. As scientists, the challenge lies in understanding how minute changes in molecular structures can lead to significant shifts in functionality and efficacy.

Synonyms
CHEMBL53236
BDBM84930
NSC_107989
CAS_60634-51-7
L000859
Q2619187