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2-Hexyloxybenzamide

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Identification
Molecular formula
C13H19NO2
CAS number
21743-74-0
IUPAC name
2-hexoxybenzamide
State
State

At room temperature, 2-hexyloxybenzamide is typically a solid. It has a crystalline form and can be handled as a powder.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.00
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.00
General information
Molecular weight
235.30g/mol
Molar mass
235.3220g/mol
Density
1.0700g/cm3
Appearence

2-Hexyloxybenzamide appears as a white or off-white crystalline solid. Its crystalline structure allows it to be solid at room temperature, and it does not have a distinct odor.

Comment on solubility

Solubility of 2-hexoxybenzamide

2-hexoxybenzamide, with the chemical formula C13H19NO2, exhibits interesting solubility characteristics due to its unique structure.

General Properties

As an aromatic compound, the solubility of 2-hexoxybenzamide can be influenced by the following factors:

  • Polarity: The presence of the amide functional group contributes to its polarity, allowing for greater interactions with polar solvents.
  • Hydrophobic Alkyl Chain: The hexoxy group introduces a hydrophobic character, which can enhance solubility in nonpolar organic solvents.

Solvent Compatibility

Based on its structure, 2-hexoxybenzamide tends to be:

  • Soluble in polar organic solvents: For instance, it may dissolve well in solvents such as ethanol and methanol.
  • Less soluble in water: Owing to the hydrophobic hexoxy portion, its ability to interact with water is limited.

In summary, while 2-hexoxybenzamide shows some degree of solubility in polar solvents, its overall solubility profile is more favorable in organic solvents due to the balance of hydrophilic and hydrophobic interactions present in its molecular structure.

Interesting facts

Interesting Facts about 2-Hexoxybenzamide

2-Hexoxybenzamide is an intriguing compound that belongs to a class known as amides. This particular amide showcases the fascinating intersection of organic chemistry and functional materials. Here are some compelling details about this compound:

  • Amide Bond Formation: 2-Hexoxybenzamide contains an amide functional group, characterized by the presence of a carbonyl group (C=O) directly attached to a nitrogen atom. This structure plays a crucial role in the compound's reactivity and properties.
  • Applications in Drug Development: Compounds that contain aromatic amides, like 2-hexoxybenzamide, are often studied for their potential therapeutic applications. They can mimic biological processes, making them candidates for drug development in fields such as anti-inflammatory and analgesic therapies.
  • Importance of Alkoxy Chains: The hexoxy group in this compound is notable as it can influence solubility and lipophilicity. This property is essential in pharmacology, as it affects how the compound interacts with biological membranes.
  • Research Relevance: Research involving 2-hexoxybenzamide can lead to insights into the stability of amide bonds under various conditions. Such investigations are critical for understanding the behavior of similar compounds in both natural and synthetic environments.
  • Green Chemistry Considerations: The synthesis of 2-hexoxybenzamide can be approached from a green chemistry perspective, aiming for eco-friendly methods to reduce waste and enhance sustainability in chemical production.

In summary, 2-hexoxybenzamide not only serves as a significant subject of study in organic chemistry but also offers potential applications across various scientific domains. Its unique structure and functional properties make it an important compound for researchers and chemists alike.

Synonyms
exalamide
53370-90-4
2-(Hexyloxy)benzamide
Hyperan
2-hexoxybenzamide
2-n-Hexyloxybenzamide
Exalamida
o-(Hexyloxy)benzamide
Benzamide, 2-(hexyloxy)-
o-Hexyloxybenzamide
2-Hexyloxybenzamide
Exalamidum
NSC-758449
7JEC65JCG2
DTXSID9045899
CHEBI:31585
NCGC00095049-01
DTXCID7025899
Exalamide [INN:JAN]
Exalamidum [INN-Latin]
Exalamida [INN-Spanish]
CAS-53370-90-4
H.P. 216
EINECS 258-504-3
UNII-7JEC65JCG2
BRN 2645003
BENZAMIDE, o-HEXYLOXY-
ortho-hexyloxybenzamide
Spectrum_001729
Exalamide (JAN/INN)
EXALAMIDE [INN]
EXALAMIDE [JAN]
EXALAMIDE [MI]
Spectrum2_000869
Spectrum5_001095
EXALAMIDE [WHO-DD]
KBioSS_002209
DivK1c_000140
SCHEMBL151112
SPECTRUM1503403
SPBio_000917
CHEMBL1405973
HMS500G22
KBio1_000140
KBio2_002209
KBio2_004777
KBio2_007345
NINDS_000140
HMS1922C12
Pharmakon1600-01503403
HY-B1224
Tox21 111403
Tox21_111403
CCG-39743
NSC758449
AKOS016014129
Tox21_111403_1
CS-4872
FE23210
NSC 758449
IDI1_000140
NCGC00095049-02
NCGC00095049-04
MS-23235
SBI-0051822.P002
DB-052320
NS00032734
D01585
F85259
AB00052353_02
SR-01000872750
SR-01000872750-1
BRD-K12609457-001-02-3
BRD-K12609457-001-03-1
Q27114461