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2-Fluoropalmitic acid

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Identification
Molecular formula
C16H31FO2
CAS number
2442-14-6
IUPAC name
2-fluorohexadecanoic acid
State
State

2-Fluoropalmitic acid is solid at room temperature.

Melting point (Celsius)
64.00
Melting point (Kelvin)
337.15
Boiling point (Celsius)
360.00
Boiling point (Kelvin)
633.15
General information
Molecular weight
260.43g/mol
Molar mass
260.3590g/mol
Density
0.9645g/cm3
Appearence

2-Fluoropalmitic acid is typically a white to off-white solid, and it may appear as a powder or in crystalline form.

Comment on solubility

Solubility of 2-fluorohexadecanoic acid (C16H31FO2)

The solubility of 2-fluorohexadecanoic acid can be characterized by various intriguing aspects. This fatty acid, having both a hydrophobic hydrocarbon chain and a polar functional group, displays unique solubility properties:

  • Moderate Solubility in Organic Solvents: 2-fluorohexadecanoic acid is typically soluble in organic solvents such as ethanol, acetone, and chloroform. This is largely due to its long chain structure, which favors interactions with non-polar solvents.
  • Poor Solubility in Water: In contrast, this compound exhibits very low solubility in water. This is attributed to the long hydrocarbon tail, which is hydrophobic and does not interact favorably with water molecules.
  • Influence of Temperature: Solubility may increase with temperature, as is common with many organic compounds, leading to increased molecular motion and interactions with solvents.
  • Potential Applications: Understanding the solubility of 2-fluorohexadecanoic acid could be crucial for applications in the fields of biochemistry and medicinal chemistry, especially when considering its behavior in biological systems.

Overall, the solubility of 2-fluorohexadecanoic acid reflects a delicate balance between its polar and non-polar characteristics. Therefore, it is essential to consider both the environmental context and solvent choice when working with this compound.

Interesting facts

Interesting Facts about 2-Fluorohexadecanoic Acid

2-Fluorohexadecanoic acid, also known as a fluorinated fatty acid, is a fascinating compound that highlights the interplay between organic chemistry and biochemistry. Here are some intriguing aspects of this compound:

  • Fluorinated Compounds: The presence of fluorine in the structure enhances the stability and lipophilicity of fatty acids. This characteristic is of great interest in medicinal chemistry, where such modifications can improve biological activity.
  • Applications in Research: 2-Fluorohexadecanoic acid is often used as a tool in biochemical studies. It can serve as a substrate in enzyme assays or as a tracer in metabolic studies, providing insights into lipid metabolism.
  • Biological Impact: The introduction of fluorine atoms can alter the interactions of the fatty acid with cell membranes, leading to unique biological effects. Research has shown that fluorinated fatty acids can influence cell signaling pathways, impacting processes such as inflammation.
  • Chiral Nature: 2-Fluorohexadecanoic acid can exist as different enantiomers due to the presence of a chiral center. This aspect opens up discussions about stereochemistry and its influence on biological activity and therapeutic efficacy.
  • Sustainability Concerns: While the fluorination of organic compounds can enhance their chemical properties, it is essential to consider the environmental impact of fluorinated substances. The persistence of such compounds in the environment raises questions about their long-term ecological effects.

As the study of fluorinated compounds continues to expand, 2-fluorohexadecanoic acid remains a key subject in understanding the implications of molecular design in biology and medicine. With ongoing research, this compound might unlock new avenues in drug development and metabolic engineering.

Synonyms
2-fluoropalmitic acid
2-Fluorohexadecanoic acid
16518-94-8
Hexadecanoic acid, 2-fluoro-
89270-22-4
2-Fluoro palmitic acid
NSC 158288
2-fluoro-hexadecanoic acid
2-Fluoropalmitic acid Activity: Acyl-CoA synthase inhibitor
DL-alpha-Fluoropalmitic acid
fluoropalmitic acid
starbld0019658
CBiol_002000
BSPBio_001415
KBioGR_000135
KBioSS_000135
SCHEMBL337296
BML3-C06
CHEMBL1373832
CHEBI:94978
KBio2_000135
KBio2_002703
KBio2_005271
KBio3_000269
KBio3_000270
JGRIJJOLCNCSNX-UHFFFAOYSA-N
Bio1_000286
Bio1_000775
Bio1_001264
Bio2_000135
Bio2_000615
DTXSID001347659
HMS1361G17
HMS1791G17
HMS1989G17
HMS3402G17
HMS3649L15
LMFA01090041
NSC158288
AKOS022181448
NSC-158288
IDI1_033885
NCGC00161355-01
NCGC00161355-02
NCGC00161355-03
MS-23907
PD020524
HY-117651
CS-0066744
NS00096591
SR-01000946674
SR-01000946674-1
BRD-A94451536-001-01-0
Q27166740