Interesting facts
Interesting Facts about 2-Ethylsulfanyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine
The compound 2-ethylsulfanyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine belongs to the phenothiazine class, which is known for its extensive use in pharmacology. Here are some fascinating aspects of this compound:
- Pharmacological Significance: Phenothiazines and their derivatives, including this compound, have been widely used as antipsychotic drugs. They function primarily as dopamine antagonists, which help in treating schizophrenia and other mental disorders.
- Structural Diversity: The unique modifications in its structure, such as the ethyl sulfanyl and the piperazine moieties, contribute to its biological activity and selectivity. The presence of these substituents can affect the lipophilicity and ionization of the compound, influencing its pharmacokinetics.
- Research Interest: Compounds like this one are often subjects of ongoing research to enhance therapeutic effects and reduce side effects. Its potential applications in other areas, such as treating anxiety or mood disorders, are of great interest.
- Targeted Drug Design: 2-ethylsulfanyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine showcases the principles of targeted drug design, where specific substituents are introduced to improve the mechanism of action on desired pathways.
As with many chemical compounds, the study of 2-ethylsulfanyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine opens up exciting opportunities in medicinal chemistry and therapeutic development.
Synonyms
thiethylperazine
1420-55-9
ETHYLTHIOPERAZINE
Torecan
Tietilperazina
Thiethylperazinum
Thiethylpipezazine
Theithylperazine
Tietilperazina [DCIT]
Norzine
Thiethylperazinum [INN-Latin]
Thiethylperazine [USAN:INN:BAN]
HSDB 3400
8ETK1WAF6R
EINECS 215-819-0
2-(ethylthio)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine
CHEBI:9544
3-Ethylmercapto-10-(1'-methylpiperazinyl-4'-propyl)phenothiazine
10H-Phenothiazine, 2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)-
2-(ethylsulfanyl)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine
THIETHYLPERAZINE [MI]
THIETHYLPERAZINE [INN]
THIETHYLPERAZINE [HSDB]
THIETHYLPERAZINE [USAN]
THIETHYLPERAZINE [VANDF]
DTXSID1023651
THIETHYLPERAZINE [MART.]
THIETHYLPERAZINE [WHO-DD]
2-(Ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine
2-ethylsulfanyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine
Phenothiazine, 2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)-
1179-69-7
2-Ethylthio-10-(3-(4-methylpiperazin-1-yl)propyl)phenothiazine
2-(Ethylthio)-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine
2-(ethylthio)-10-(3-(4-methylpiperazin-1-yl)propyl)-10H-phenothiazine
10H-Phenothiazine, 2-(ethylthio)-10-[3-(4-methyl-1-piperazinyl)propyl]-
Thiethylperazinum (INN-Latin)
THIETHYLPERAZINE (MART.)
Thioethylperazine
MLS002154140
Phenothiazine, 2-(ethylthio)-10-[3-(4-methyl-1-piperazinyl)propyl]-
NSC130044
Norzine (*Dimaleate*)
SMR001233447
UNII-8ETK1WAF6R
GS-95 (*Dimaleate*)
Thiethylperazine (USAN/INN)
2-(ethylsulfanyl)-10-(3-(4-methylpiperazin-1-yl)propyl)-10H-phenothiazine
Norzine (Salt/Mix)
Torecan (Salt/Mix)
Tresten (Salt/Mix)
CHEMBL1378
SCHEMBL49124
DTXCID403651
GTPL7306
BDBM78436
cid_3085006
R06AD03
BCP09601
HY-B1794
Thiethylperazine maleate (Salt/Mix)
EX-A10897
DB00372
NCGC00262537-04
DA-78419
MS-26778
AB00514742
CS-0013829
NS00004048
C07132
D02354
H27367
EN300-19766526
L000871
Q372725
BRD-K69600043-328-05-5
2-(Ethylthio)-10-[3-(4-methyl-1-piperazinyl)propyl]phenthiazine
2-(ethylthio)-10-[3-(4-methylpiperazino)propyl]phenothiazine;malic acid
2-(Ethylsulfanyl)-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine #
2-(ethylthio)-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine;2-hydroxybutanedioic acid
2-ethylsulfanyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;2-oxidanylbutanedioic acid
215-819-0
Solubility of 2-ethylsulfanyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine
The solubility of the compound 2-ethylsulfanyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine, with the chemical formula C21H24F3N3S, can be influenced by several factors:
In general, compounds such as this one, which incorporate aromatic systems and sulfur compounds, exhibit limited water solubility. However, they are likely to be more soluble in organic solvents such as ethanol or dichloromethane.
As with many such compounds, it's essential to conduct specific solubility tests to determine their behavior in various environments. Understanding the solubility will not only help in optimizing their use in applications but also in predicting their behavior in biological systems.