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2-Ethoxybenzamide

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Identification
Molecular formula
C9H11NO2
CAS number
588-70-1
IUPAC name
2-ethoxybenzamide
State
State

At room temperature, 2-ethoxybenzamide is in a solid state. It remains solid until it reaches its melting point at 95 °C, at which it transitions to a liquid state.

Melting point (Celsius)
95.00
Melting point (Kelvin)
368.15
Boiling point (Celsius)
318.50
Boiling point (Kelvin)
591.70
General information
Molecular weight
165.19g/mol
Molar mass
165.1900g/mol
Density
1.1560g/cm3
Appearence

2-Ethoxybenzamide appears as a white to off-white crystalline solid. It may form powder or fine needle-like crystals. The compound is typically stable under normal conditions and should be handled with care to avoid any potential decomposition or reaction with incompatible materials.

Comment on solubility

Solubility of 2-ethoxybenzamide

2-ethoxybenzamide, with the chemical formula C9H11NO2, exhibits moderate solubility characteristics, making it an interesting compound in solutions. Here are some key points regarding its solubility:

  • Polar vs. Nonpolar: The presence of an amide functional group contributes to its polar character, while the ethoxy group lends some nonpolar characteristics.
  • Solvent Compatibility: 2-ethoxybenzamide is known to be more soluble in polar solvents such as water and ethanol compared to nonpolar solvents like hexane.
  • Temperature Dependence: As with many organic compounds, solubility in water may increase with temperature, allowing for greater dissolution at higher temperatures.

In summary, while 2-ethoxybenzamide is not highly soluble in water, its solubility is sufficient in various polar solvents, thus making it useful in multiple applications where solubility plays a critical role. Understanding its solubility helps in determining the conditions needed for its effective use in chemical processes.

Interesting facts

Exploring 2-Ethoxybenzamide

2-Ethoxybenzamide is a fascinating compound with intriguing characteristics and applications in various fields of chemistry. Here are some interesting facts:

  • Structure and Bonding: This compound features a benzene ring substituted with an ethoxy group and an amide functional group. The presence of both functional groups provides unique properties that lend themselves to diverse chemical reactivities.
  • Pharmaceutical Applications: 2-Ethoxybenzamide and its derivatives have been studied for their potential roles in the pharmaceutical industry. Their ability to act as intermediates in drug synthesis is particularly noteworthy, as they can influence biological activity.
  • Biochemical Relevance: Research indicates that compounds with amide functionalities, like 2-ethoxybenzamide, often participate in hydrogen bonding, which is crucial for biological recognition processes. This has implications for drug design, particularly in enhancing the specificity of drug-receptor interactions.
  • Polarity and Interaction: The ethoxy group imparts unique solubility characteristics, allowing 2-ethoxybenzamide to interact differently in various solvents. Its polar nature makes it an interesting subject of study for solvation dynamics and reactivity in organic reactions.
  • Research Applications: Beyond pharmaceuticals, 2-ethoxybenzamide is also investigated in materials science for potential applications in polymer synthesis and as a reagent in organic synthesis. Its versatility makes it a compound of interest in both fundamental and applied research.

In conclusion, 2-ethoxybenzamide serves as a prime example of how a compound's structure and functional groups can dictate its potential in both theoretical studies and practical applications. As the scientific community continues to explore its properties, new insights and innovations are likely to emerge!

Synonyms
2-ETHOXYBENZAMIDE
ethenzamide
938-73-8
o-Ethoxybenzamide
Benzamide, 2-ethoxy-
Etenzamide
Ethbenzamide
Ethenzamid
Ethosalicyl
Lucamide
Pirosolvina
Etamide
Etosalicil
Etosalicyl
Katagrippe
Protopyrin
Trancalgyl
Anovigam
Etocil
Eusal
Benzamide, o-ethoxy-
Etenzamida
Etenzamide [DCIT]
Ethenzamidum
Ethoxybenzamide
Etenzamida [INN-Spanish]
Ethenzamidum [INN-Latin]
NSC 28787
CCRIS 9124
UNII-L929ZCK4BF
EINECS 213-346-4
L929ZCK4BF
Ethenzamide (TN)
MFCD00007977
NSC-28787
Ethenzamide [INN:BAN:JAN]
BRN 2208582
DTXSID4020581
H.P. 209
ETHENZAMIDE [MI]
ETHENZAMIDE [INN]
ETHENZAMIDE [JAN]
Ethenzamide (JP17/INN)
J3.352I
ETHENZAMIDE [MART.]
ETHENZAMIDE [WHO-DD]
DTXCID40581
4-10-00-00175 (Beilstein Handbook Reference)
NCGC00091616-01
Ethenzamide 100 microg/mL in Acetonitrile
Etenzamida (INN-Spanish)
Ethenzamidum (INN-Latin)
ETHENZAMIDE (MART.)
2-ethoxy-benzamide
2-Eethoxybenzamide
CAS-938-73-8
Ethanzamide
Orthoethoxybenzamide
2-Ethoxybenzoylamide
2-Ethoxybenzamide, 97%
WLN: ZVR BO2
SCHEMBL25624
2-Ethoxybenzamide (Standard)
MLS002302987
CHEMBL1483877
CHEBI:31564
HY-B1428R
N02BA07
HMS3039J16
Ethenzamide 1.0 mg/ml in Methanol
HY-B1428
NSC28787
Tox21_111156
Tox21_200025
s4524
STK105005
AKOS003280312
Tox21_111156_1
CCG-213844
CS-4916
DB13544
FE34644
KS-5320
NCGC00091616-02
NCGC00091616-03
NCGC00257579-01
AC-11991
SMR001307304
SY015492
DB-057442
DB-370072
E0222
NS00002670
D01466
D70657
SBI-0653503.0001
AB01010349_03
EN300-6492973
Q553324
SR-01000877236
SR-01000877236-2
BRD-K88308881-001-06-8
Z54953371
213-346-4