Skip to main content

Fexofenadine

ADVERTISEMENT
Identification
Molecular formula
C32H39NO4
CAS number
83799-24-0
IUPAC name
2-ethoxy-4-[2-[[3-methyl-1-[2-(1-piperidyl)phenyl]butyl]amino]-2-oxo-ethyl]benzoic acid
State
State

At room temperature, Fexofenadine exists as a solid in the form of a white to off-white crystalline powder.

Melting point (Celsius)
195.00
Melting point (Kelvin)
468.15
Boiling point (Celsius)
540.00
Boiling point (Kelvin)
813.15
General information
Molecular weight
501.67g/mol
Molar mass
501.6660g/mol
Density
1.3562g/cm3
Appearence

Fexofenadine is typically encountered as a white to off-white crystalline powder. It is odorless and is known to have a slightly bitter taste. The pure compound is usually found in its solid form and sometimes may appear hygroscopic.

Comment on solubility

Solubility of 2-ethoxy-4-[2-[[3-methyl-1-[2-(1-piperidyl)phenyl]butyl]amino]-2-oxo-ethyl]benzoic acid

The solubility of 2-ethoxy-4-[2-[[3-methyl-1-[2-(1-piperidyl)phenyl]butyl]amino]-2-oxo-ethyl]benzoic acid (C32H39NO4) is influenced by several factors due to its complex structure. This compound features both hydrophobic segments (the bulky aromatic rings and the piperidine moiety) and potentially hydrophilic segments (the carboxylic acid group). As a result:

  • Hydrophobic Interactions: The aromatic and aliphatic portions of the molecule may lead to poor solubility in polar solvents, such as water.
  • Hydrophilic Groups: The presence of the carboxylic acid moiety suggests that the compound may exhibit some solubility in solvents that can engage in hydrogen bonding.
  • Solvent Choice: This compound is more likely to be soluble in organic solvents like DMSO or methanol rather than in water.
  • pH Dependence: The solubility may also vary significantly with changes in pH, particularly due to the ionization of the carboxylic acid group, which can facilitate solubility in aqueous environments.

Thus, one can conclude that while 2-ethoxy-4-[2-[[3-methyl-1-[2-(1-piperidyl)phenyl]butyl]amino]-2-oxo-ethyl]benzoic acid may display variable solubility characteristics depending on the solvent used and environmental pH, careful selection of solvents is essential for maximizing its solubility.

Interesting facts

Interesting Facts about 2-Ethoxy-4-[2-[[3-methyl-1-[2-(1-piperidyl)phenyl]butyl]amino]-2-oxo-ethyl]benzoic acid

The compound 2-Ethoxy-4-[2-[[3-methyl-1-[2-(1-piperidyl)phenyl]butyl]amino]-2-oxo-ethyl]benzoic acid is a fascinating molecule with several noteworthy aspects:

  • Pharmaceutical Potential: This compound has garnered attention in medicinal chemistry, particularly for its potential role as a therapeutic agent. The intricate structure provides insight into its ability to interact with biological targets.
  • Structure Complexity: The molecule contains a unique arrangement of aromatic systems and functional groups, including an ethoxy group, benzoic acid moiety, and a piperidine ring. This complexity often correlates with diverse biological activity.
  • Bioactivity: Compounds with similar structures have been studied for their effects in areas such as anti-inflammatory and anticancer research, showcasing the importance of functional modifications to enhance efficacy.
  • Manifold Applications: Beyond pharmaceutical applications, such compounds often find utility in various fields, including material science and organic synthesis, due to their reactive functional groups.
  • Medicinal Chemistry Studies: Research focused on modifying this compound can lead to derivatives with improved activity or reduced side effects, emphasizing its importance in the drug discovery process.

In summary, 2-Ethoxy-4-[2-[[3-methyl-1-[2-(1-piperidyl)phenyl]butyl]amino]-2-oxo-ethyl]benzoic acid is not just a chemical compound; it is a stepping stone in the quest for novel therapeutic agents that can lead to breakthroughs in the treatment of various diseases. As research advances, the potential applications of this compound may expand, making it a subject of ongoing interest in the field of chemistry.

Synonyms
135969-54-9
2-ethoxy-4-[2-[[3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino]-2-oxoethyl]benzoic acid
108157-53-5
2-ethoxy-4-[2-[[3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]Benzoic acid
AG-EE-388 ZW
2-ethoxy-4-(2-((3-methyl-1-(2-(piperidin-1-yl)phenyl)butyl)amino)-2-oxoethyl)benzoic acid
2-Ethoxy-4-[2-({3-Methyl-1-[2-(1-Piperidinyl)Phenyl]Butyl}Amino)-2-Oxoethyl]Benzoic Acid
2-Ethoxy-4-[2-({3-methyl-1-[2-(piperidin-1-yl)phenyl]butyl}amino)-2-oxoethyl]benzoic acid
Oprea1_101414
SCHEMBL163867
CHEMBL356866
DTXSID00861330
FAEKWTJYAYMJKF-UHFFFAOYSA-N
HMS3372O15
HMS3393N08
HMS3654N06
HMS3744E11
2-ethoxy-4-[2-[[(1R)-3-Methyl-1-[2-(piperidin-1- yl)phenyl]butyl]aMino]-2-oxoethyl]benzoic acid
AKOS025243713
NCGC00389315-01
SY046828
DB-042264
DB-251459
DB-338370
NS00000620
2-ethoxy-4-[N-{1-(2-piperidino-phenyl)-3-methyl-1-butyl}-aminocarbonylmethyl]-benzoic acid
2-ethoxy-4-[N-{1-(2-piperidinophenyl)-3-methyl-1-butyl}-aminocarbonylmethyl]-benzoic acid
(S)-2-Ethoxy-4-[2-[[3-methyl-1-[2-(1-piperidyl)phenyl]butyl]amino]-2-oxoethyl]benzoic Acid
Benzoic acid, 2-ethoxy-4-[2-[[3-Methyl-1-[2-(1-piperidinyl)phenyl]butyl]aMino]-2-oxoethyl]-