Interesting facts
Interesting Facts about 2-Ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic Acid
2-Ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid is a fascinating compound that showcases the beauty of organic chemistry through its complex structure and potential applications. Here are some intriguing aspects:
- Innovative Structure: The compound consists of a benzimidazole ring system fused with a tetrazole moiety, which is known for its diverse chemical reactivity and biological activity. This unique combination presents opportunities for the development of novel pharmacological agents.
- Pharmaceutical Potential: Compounds containing both tetrazole and benzimidazole rings have been extensively studied for their therapeutic properties. They may serve as potential anti-inflammatory, analgesic, and anticancer agents, making them of significant interest in medicinal chemistry.
- Biological Activities: The presence of the tetrazole group has been linked to various biological activities, including antimicrobial and anti-tumor effects. This opens avenues for research in drug development aimed at targeting specific diseases.
- Versatility: The ethoxy group present in the compound can influence solubility and overall bioactivity, which is crucial for optimizing drug formulations. Adjusting substituents allows chemists to fine-tune the efficacy and safety profiles of similar compounds.
- Synthetic Utility: The synthesis of this compound may involve multi-step processes, showcasing the importance of technique and strategy in organic synthesis. Such complexity offers students an excellent opportunity to explore modern synthetic methodologies.
Overall, 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid illustrates the intricate connection between chemical structure and biological function, making it a notable subject of study for both chemists and pharmacologists alike. As stated by renowned chemist Linus Pauling, "Chemistry is the stories we tell about matter." This compound certainly adds a compelling chapter to the tale!
Synonyms
candesartan
139481-59-7
CV-11974
1-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid
2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid
CANDEMORE
UNII-S8Q36MD2XX
S8Q36MD2XX
NSC-759858
2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxylic acid
CHEBI:3347
DTXSID0022725
HSDB 7520
TCV-116 (prodrug)
MFCD00864463
CHEMBL1016
DTXCID202725
EC 604-138-8
NSC 759858
1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-
NCGC00167474-01
1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid
CV 11974
C24H20N6O3
[3H]candesartan
2-Ethoxy-1-((2-(1H-tetrazole-5-yl)biphenyl-4-yl)methyl)-1H-benzamidazole-7-carboxylic acid.
2-ethoxy-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid
1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid
2-(ethyloxy)-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid
2-ethoxy-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-1H-benzimidazole-7-carboxylic acid
2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benzimidazole-7-carboxylic acid
Candesartan [INN]
CAS-139481-59-7
SR-05000001447
Candesartan (USAN/INN)
candesartanum
Candesartan [USAN:INN:BAN]
Candesartan cilexetil related compound G;Candesartan cilexetil impurity G
2-ethoxy-1-((2'-(1H-tetrazol-5-yl)biphenyl-4ethyl))-1H-benzimidazole-7-carboxylic acid
2-ethoxy-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4ethyl]}-1H-benzimidazole-7-carboxylic acid
2-ethoxy-1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1H-benzimidazole-7-carboxylic acid
2-ethoxy-7-carboxy-1-(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methylbenzimidazole
CELEXETIL
candesartan (Atacand)
KS-5003
Candesartan (Standard)
CANDESARTAN [MI]
CANDESARTAN [HSDB]
CANDESARTAN [USAN]
CANDESARTAN [VANDF]
SCHEMBL3938
2-ethoxy-3-[[4-[2-(1h-tetrazol-5-yl)phenyl]phenyl]methyl]-3h-benzoimidazole-4-carboxylic acid
CANDESARTAN [WHO-DD]
GTPL587
Candesartan 100 microg/mL in Acetonitrile:Methanol
MLS003915631
MLS004774041
BIDD:GT0350
GTPL6907
Candesartan - Bio-X trade mark
HY-B0205R
C09CA06
BCPP000302
HMS2089M22
HMS3651C13
HMS3715F13
Pharmakon1600-01502288
BCP01137
HY-B0205
STR09609
Tox21_112478
BDBM50240609
NSC755311
NSC759858
s1578
AKOS015888154
AKOS025117340
Tox21_112478_1
AB07470
BCP9000479
CCG-213059
CCG-269122
DB13919
FC09818
NSC-755311
NCGC00167474-02
NCGC00167474-04
NCGC00167474-06
2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid (Candesartan)
2-Ethoxy-3-[[4-[2-(1H-tetrazol-5-yl)phenyl]phenyl] methyl]-3H-benzoimidazole-4-carboxylic acid
BC164271
SMR002203608
SMR003500711
SY065768
NS00009281
SW199612-2
C07468
D00522
AB01275447-01
AB01275447_02
AB01275447_03
EN300-6491073
A808309
L000156
Q415970
SR-05000001447-1
SR-05000001447-2
SR-05000001447-5
BRD-K84091759-001-07-1
BRD-K84091759-001-08-9
CANDESARTAN CILEXETIL IMPURITY G [EP IMPURITY]
Z1741968269
2-Ethoxy-1-[[2'-(1 H-tetrazol-5-yl)biphenyl-4-yl]methyl]-benzimidazole-7-carboxylic acid
2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-benzimidazole-7-carboxylic acid
2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic Acid
2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-4-benzimidazolecarboxylic acid
2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzimidazole-4-carboxylic acid
1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylicacid
1-[(2 inverted exclamation mark -(5-Tetrazolyl)-4-biphenylyl)methyl]-2-ethoxybenzimidazole-7-carboxylic Acid
2-ethoxy-1-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1H-1,3-benzodiazole-7-carboxylic acid
2-ethoxy-1-[[2'-(2h-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1h-benzimidazole-7-carboxylic acid
2-ethoxy-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1H-1,3-benzodiazole-7-carboxylic acid
2-ethoxy-1-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1H-1,3-benzodiazole-7-carboxylic acid
2-Ethoxy-3-((4-(2-(2H-tetrazol-5-yl)phenyl)phenyl)methyl)-3H-benzoimidazole-4-carboxylic Acid
2-ethoxy-3-[[4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid
2-ethoxy-3-[2''-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid
2-Ethoxy-3-[2''-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid(CV-11974)
2-Ethoxy-3-[2''-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid
2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid
Solubility of 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid
The compound 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid, with the chemical formula C24H21N3O4, exhibits intriguing solubility characteristics. Understanding its solubility is crucial for applications in pharmaceuticals and material science. Here are some key points about its solubility:
In summary, the solubility profile of this compound is dictated by its intricate structure and the nature of the solvents used. As a general observation, compounds with such complex frameworks often require a tailored approach to determine their solubility in various environments.