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2-[(Dimethylamino)methyl]indan-1-one

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Identification
Molecular formula
C13H17NO
CAS number
28221-65-0
IUPAC name
2-[(dimethylamino)methyl]indan-1-one
State
State

At room temperature, 2-[(Dimethylamino)methyl]indan-1-one is typically found in a solid state. It forms a stable crystalline structure under normal conditions.

Melting point (Celsius)
72.50
Melting point (Kelvin)
345.65
Boiling point (Celsius)
327.20
Boiling point (Kelvin)
600.35
General information
Molecular weight
189.27g/mol
Molar mass
189.2650g/mol
Density
1.0100g/cm3
Appearence

2-[(Dimethylamino)methyl]indan-1-one typically appears as a crystalline solid. The crystals are often white or off-white in color. The appearance may vary based on purity and specific conditions of synthesis and storage. This compound does not exhibit any distinctive luminescence or fluorescence under standard light conditions.

Comment on solubility

Solubility of 2-[(dimethylamino)methyl]indan-1-one (C13H17NO)

The solubility of 2-[(dimethylamino)methyl]indan-1-one, a compound with a rather complex structure, can be influenced by several factors. Generally speaking, solubility is highly dependent on the polarity of the compound as well as the nature of the solvent used. Here are some key points to consider:

  • Polarity: The presence of a dimethylamino group can impart some degree of polarity to the molecule, potentially enhancing its solubility in polar solvents such as water.
  • Hydrophobic Character: The indan moiety within the compound introduces a hydrophobic region, which may lead to lower solubility in aqueous environments.
  • Solvent Interaction: It is likely that this compound would show improved solubility in polar organic solvents like methanol or ethanol, where the amino nitrogen can engage in hydrogen bonding.

In summary, while the solubility of 2-[(dimethylamino)methyl]indan-1-one may vary based on the solvent system, it's generally expected to be soluble in polar organic solvents due to its structural features. This interplay of hydrophilic and hydrophobic characteristics mirrors a common theme in organic chemistry, where the phrase "like dissolves like" often holds true.

Interesting facts

Interesting Facts about 2-[(dimethylamino)methyl]indan-1-one

2-[(Dimethylamino)methyl]indan-1-one is a fascinating chemical compound that has captured the interest of researchers due to its unique structural features and potential applications. Here are some key points to consider:

  • Structure Insights: The presence of an indanone moiety provides a unique bicyclic structure that imparts distinct properties compared to other compounds. This aromatic ring system not only influences the compound's reactivity but also enhances its stability.
  • Dimethylamino Group: The dimethylamino substituent plays a crucial role in determining the compound's basicity and nucleophilicity, allowing it to participate in various chemical reactions.
  • Potential Applications: Research indicates that this compound may find applications in medicinal chemistry, particularly in the development of pharmaceuticals. It holds promise for acting as a building block for more complex molecules.
  • Medicinal Chemistry: Compounds similar to 2-[(dimethylamino)methyl]indan-1-one are often explored for their biological activity. Studies on related indanones have suggested potential anti-inflammatory and analgesic properties.

As chemistry students and scientists delve into the world of organic compounds, the study of 2-[(dimethylamino)methyl]indan-1-one serves as an excellent example of how structural modifications can lead to a wide range of chemical behaviors and applications. Understanding such compounds is essential for advancing drug discovery and improving therapeutic outcomes.

With ongoing research, new insights and applications for this compound may emerge, further enriching the field of chemistry.

Synonyms
2-[(dimethylamino)methyl]-2,3-dihydroinden-1-one
67153-85-9
2-[(dimethylamino)methyl]-2,3-dihydro-1h-inden-1-one
SCHEMBL2175676
CHEMBL3545731
CHEBI:91638
DTXSID80274464
HSCI1_000280
2-[(dimethylamino)methyl]-1-indanone
PD136828
AK-105/40690102
BRD-A33833419-003-01-1
Q27163465
(?)-2-N,N-Dimethylaminomethyl-1-indanone hydrochloride