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Butamben Hydrochloride

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Identification
Molecular formula
C15H24ClN2O2
CAS number
14252-84-3
IUPAC name
2-(dimethylamino)ethyl 4-(butylamino)benzoate;hydrochloride
State
State

At room temperature, Butamben Hydrochloride exists as a solid. It should be handled in a controlled environment to keep its pharmaceutical efficacy intact.

Melting point (Celsius)
115.00
Melting point (Kelvin)
388.00
Boiling point (Celsius)
219.00
Boiling point (Kelvin)
492.00
General information
Molecular weight
268.79g/mol
Molar mass
268.7940g/mol
Density
1.0607g/cm3
Appearence

This compound appears as a white, crystalline powder. It is typically odorless and is used in a finely divided form for pharmaceutical applications.

Comment on solubility

Solubility of 2-(dimethylamino)ethyl 4-(butylamino)benzoate;hydrochloride

The solubility of 2-(dimethylamino)ethyl 4-(butylamino)benzoate; hydrochloride can be characterized by several important factors:

  • Solvent choice: This compound is likely to be soluble in polar solvents due to the presence of the hydrochloride moiety, which enhances its ability to interact with water molecules.
  • pH dependence: The solubility may vary with changes in pH, as the protonation state of the amine groups in the compound can significantly impact its solubility profile.
  • Temperature effects: Solubility typically increases with temperature for many salts, so heating the solution may facilitate greater solvation of the HCl salt form.
  • Structural effects: The bulky butylamino group introduces steric hindrance, which may influence solubility compared to simpler amines.

In conclusion, one can expect that the solubility of this compound is influenced by both its functional groups and external conditions. As a general rule, it is advisable to conduct solubility tests in various solvents and conditions to determine the most effective formulation for specific applications.

Interesting facts

Interesting Facts about 2-(dimethylamino)ethyl 4-(butylamino)benzoate; hydrochloride

This compound, known for its role as a pharmaceutical intermediate, holds a significant place in medicinal chemistry. The intricate structure of 2-(dimethylamino)ethyl 4-(butylamino)benzoate; hydrochloride allows it to interact effectively with biological systems, making it a target of interest in drug development.

Key Highlights:

  • Medicinal Applications: This compound is studied for its potential use in treating various health conditions, including pain management and neurological disorders.
  • Structure-Activity Relationship (SAR): The unique combination of dimethylamino and butylamino groups contributes to its biological activity, highlighting the importance of chemical modifications in enhancing therapeutic efficacy.
  • Hydrochloride Form: The hydrochloride salt form improves solubility and stability, which is crucial for drug formulation and delivery.
  • Research and Development: Ongoing studies focus on its pharmacokinetics and mechanisms of action, which could uncover new therapeutic pathways.

As a fascinating example of modern chemistry's intersection with medicine, 2-(dimethylamino)ethyl 4-(butylamino)benzoate; hydrochloride exemplifies how even subtle changes in molecular structure can lead to profound differences in drug performance. Chemists and pharmacologists continue to probe its capabilities, pushing the boundaries of what we know about compound interactions in biological systems.

In the words of a leading researcher: "The exploration of novel compounds like this one inspires breakthroughs in the relentless pursuit of better treatments."

Synonyms
Tetracaine hydrochloride
136-47-0
Tetracaine HCl
Butethanol
Curtacain
Menonasal
Pantocaine
Anethaine
Dicainum
Amethocaine hydrochloride
Anethain
Butylocaine
Decicain
Decicaine
Dessicain
Intercaine
Pantocain
Anacel
Tonexol
Gingicain M
Tetocaine
Tetraca
Tetracainium chloridum
Tetracaine chlorhydrate
Tetracaine (hydrochloride)
Tetracaine monohydrochloride
Amethocaine monohydrochloride
2-(dimethylamino)ethyl 4-(butylamino)benzoate hydrochloride
UNII-5NF5D4OPCI
5NF5D4OPCI
Tetracaine, HCl
EINECS 205-248-5
NSC-757337
2-(Dimethylamino)ethyl p-(butylamino)benzoate monohydrochloride
DTXSID6042448
4-(Butylamino)benzoic Acid 2-(Dimethylamino)ethyl Ester Hydrochloride
Benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl ester, monohydrochloride
p-Butylaminobenzoyl-2-dimethylaminoethanol hydrochloride
MLS000069780
2-(Dimethylamino)ethyl p-(butylamino)benzoate hydrochloride
2-Dimethylaminoethanol 4-N-butylaminobenzoate hydrochloride
DTXCID4022448
p-(Butylamino)benzoic acid, 2-(dimethylamino)ethyl ester, hydrochloride
Tetracaine hydrochloride [USP:JAN]
Benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl ester,monohydrochloride
MFCD00038912
Tetracaine hydrochloride (Pontocaine)
NSC 757337
Leocaine
SMR000058522
BENZOIC ACID, p-(BUTYLAMINO)-, 2-(DIMETHYLAMINO)ETHYL ESTER, MONOHYDROCHLORIDE
KOVANAZE COMPONENT TETRACAINE HYDROCHLORIDE
53762-93-9
Viractin
Tetracaine hydrochloride (USP:JAN)
TETRACAINE HYDROCHLORIDE (MART.)
TETRACAINE HYDROCHLORIDE [MART.]
TETRACAINE HYDROCHLORIDE (USP-RS)
TETRACAINE HYDROCHLORIDE [USP-RS]
TETRACAINE HYDROCHLORIDE (EP MONOGRAPH)
TETRACAINE HYDROCHLORIDE (USP MONOGRAPH)
TETRACAINE HYDROCHLORIDE [EP MONOGRAPH]
TETRACAINE HYDROCHLORIDE [USP MONOGRAPH]
SR-01000075240
NCGC00016049-02
CAS-136-47-0
Exactacain
Comfortox Tetracaine
Pontocaine Hydrochloride
Protocaine hydrochloride
Tetracaini hydrochloridum
Opera_ID_1220
NeuroMed Topical Analgesic
DICAINUM [WHO-IP]
Eclipse Topical AnalgesicLL
NeuroMed Topical AnalgesicLA
SCHEMBL24370
MLS002222164
Protocaine hydrochloride (TN)
SPECTRUM1500564
4-butylaminobenzoic acid dimethylaminoethyl ester hcl
CHEBI:9469
CHEMBL1255654
Tetracaine for system suitability
2-(dimethylamino)ethyl 4-(butylamino)benzoate;hydrochloride
Tetracaine hydrochloride, >=99%
HMS1569D04
HMS1921C17
Pharmakon1600-01500564
BCP26339
HY-B0473
Tox21_110290
Tox21_501211
AC-774
CCG-39266
NSC757337
s2573
TETRACAINE HYDROCHLORIDE [MI]
Tetracaine hydrochloride (JP18/USP)
TETRACAINE HYDROCHLORIDE [JAN]
AKOS015888160
Tox21_110290_1
FT28067
KS-5059
LP01211
TETRACAINE HYDROCHLORIDE [VANDF]
NCGC00016049-07
NCGC00094458-01
NCGC00094458-02
NCGC00094458-03
NCGC00094458-04
NCGC00094458-05
NCGC00261896-01
TETRACAINE HYDROCHLORIDE [WHO-DD]
TETRACAINE HYDROCHLORIDE [WHO-IP]
AMETHOCAINE HYDROCHLORIDE [WHO-IP]
DB-042341
EU-0101211
NS00079216
SW196411-3
T1688
TETRACAINE HYDROCHLORIDE [GREEN BOOK]
TETRACAINE HYDROCHLORIDE [ORANGE BOOK]
D00741
T 7508
EN300-6748838
TETRACAINI HYDROCHLORIDUM [WHO-IP LATIN]
A807078
Tetracaine hydrochloride, Sigma Reference Standard
SR-01000075240-1
SR-01000075240-6
Q27262597
TETRACAINE HYDROCHLORIDE COMPONENT OF KOVANAZE
Z2756516968
Tetracaine hydrochloride, meets USP testing specifications
2-(Dimethylamino)ethyl 4-(butylamino)benzoic acid hydrochloride
2-(Dimethylamino)ethyl 4-(butylamino)benzoate monohydrochloride
Tetracaine Hydrochloride 1.0 mg/ml in Acetonitrile (as free base)
Tetracaine hydrochloride, European Pharmacopoeia (EP) Reference Standard
Tetracaine for system suitability, European Pharmacopoeia (EP) Reference Standard
Tetracaine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material
Tetracaine hydrochloride, United States Pharmacopeia (USP) Reference Standard
205-248-5
4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester hydrochloride;2-Dimethylaminoethanol 4-n-butylaminobenzoate hydrochloride;Am ethocaine hydrochloride;Tetracaine hydrochloride