Skip to main content

Phenanthridinone derivative

ADVERTISEMENT
Identification
Molecular formula
C17H15N3O2
CAS number
17321-67-0
IUPAC name
2-(dimethylamino)-N-(6-oxo-5H-phenanthridin-2-yl)acetamide
State
State
Solid at room temperature and pressure, typically exists in a crystalline form often used in research and industrial processes.
Melting point (Celsius)
180.00
Melting point (Kelvin)
453.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
277.32g/mol
Molar mass
277.3100g/mol
Density
1.2400g/cm3
Appearence

The compound is typically found as a crystalline solid with a pale yellow coloration. The appearance may vary slightly based on impurities and form, whether it's a powder or larger crystals.

Comment on solubility

Solubility of 2-(Dimethylamino)-N-(6-oxo-5H-phenanthridin-2-yl)acetamide

The solubility of 2-(dimethylamino)-N-(6-oxo-5H-phenanthridin-2-yl)acetamide, with the chemical formula C17H15N3O2, can be influenced by several factors, making it an interesting compound to study. While specific solubility data for this particular compound may not be extensively documented, we can discuss general principles of solubility that apply:

  • Polarity: The presence of dimethylamino and carbonyl (6-oxo) groups suggests potential for hydrogen bonding, which often increases solubility in polar solvents.
  • Solvent Compatibility: It is likely to be soluble in organic solvents such as ethanol or dimethyl sulfoxide (DMSO), but may exhibit limited solubility in non-polar solvents due to its structure.
  • Temperature Effects: As with many compounds, increased temperature may enhance the solubility, allowing for more effective dissolution in suitable solvents.

In practice, one might observe that the compound's solubility can vary with pH changes and complex formation, particularly in biological systems where fluctuations in the microenvironment can impact solubility significantly.

Ultimately, understanding the solubility behavior of this compound is crucial for its application in various chemical and pharmaceutical contexts.

Interesting facts

Interesting Facts about 2-(dimethylamino)-N-(6-oxo-5H-phenanthridin-2-yl)acetamide

The compound 2-(dimethylamino)-N-(6-oxo-5H-phenanthridin-2-yl)acetamide, often referred to in scientific circles as a novel phenanthridine derivative, is intriguing not only for its structure but also for its potential applications. Here are some fascinating insights:

  • Pharmacological Potential: Compounds like this one with the phenanthridine skeleton are known for their diverse biological activities, including antitumor, antiviral, and antimicrobial properties. This particular derivative may offer a pathway for new therapeutic agents.
  • Structure-Activity Relationship (SAR): Understanding how variations in the structure influence biological activity can lead to the development of more effective drugs. The dimethylamino group can enhance solubility and receptor binding, thereby modifying the pharmacokinetics of the compound.
  • Research Opportunities: Ongoing research into this compound includes investigations into its mechanism of action and the potential for modification to improve efficacy and reduce side effects. This opens numerous avenues for research, inviting scientists to explore its full potential.
  • Synthetic Work: The synthesis of such complex organic molecules often requires advanced techniques in organic chemistry, including reductive amination and cyclization. Understanding the synthetic pathways can also inspire new methodologies in chemical synthesis.

In conclusion, 2-(dimethylamino)-N-(6-oxo-5H-phenanthridin-2-yl)acetamide is more than just a chemical compound; it represents a significant area of interest for those studying medicinal chemistry and drug discovery. As researchers continue to uncover the characteristics and potential uses of this compound, it adds to the rich tapestry of knowledge that defines the field of chemistry.

Synonyms
PJ34
344458-19-1
pj-34
N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE
2-(dimethylamino)-N-(6-oxo-5H-phenanthridin-2-yl)acetamide
2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridin-2-yl)acetamide
Acetamide, N-(5,6-dihydro-6-oxo-2-phenanthridinyl)-2-(dimethylamino)-
CHEMBL372303
P34
N-(5,6-dihydro-6-oxo-2-phenanthridinyl)-2-(dimethylamino)acetamide
PJ 34
UYJZZVDLGDDTCL-UHFFFAOYSA-N
PJ34 free base
PJ34(free base)?
1xk9
NA92ZAR7N2
SCHEMBL422317
BDBM27497
GTPL11348
CHEBI:167900
DTXSID201339305
GLXC-10756
HMS3651B06
BCP07990
EX-A3801
UNA45819
HY-13688A
AKOS030229047
CS-1463
DB08348
SB19292
NCGC00370866-10
AS-76486
DA-42692
NS00068150
SW219891-2
G60960
BRD-K11853856-001-01-7
BRD-K11853856-001-02-5
BRD-K11853856-003-01-3
Q27097563
2-(dimethylaminoacetylamino)-5,6-dihydrophenanthridine-6-one
2-(dimethylamino)-N-(5,6-dihydro-6-oxophenanthridin-2yl)acetamide
2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin-2-yl)-acetamide
N-(6-oxo-5,6-dihydro- phenanthridin-2-yl)-N,N-dimethylacetamide
N(2),N(2)-dimethyl-N-(6-oxo-5,6-dihydrophenanthridin-2-yl)glycinamide
N-(5,6-Dihydro-6-oxo-2-phenanthridinyl)-2-(dimethylamino)-acetamide
N-(5,6-dihydro-6-oxophenanthridine-2-yl)-2-(dimethylamino)acetamide
n-(6-oxo-5,6-dihydrophenanthridin-2-yl)-2-(n,n-dimethylamino)acetamide
N~2~,N~2~-dimethyl-N-(6-oxo-5,6-dihydrophenanthridin-2-yl)glycinamide
356042-41-6