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Procaine hydrochloride

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Identification
Molecular formula
C13H21ClN2O2
CAS number
51-05-8
IUPAC name
2-(diethylamino)ethyl 4-aminobenzoate;hydrochloride
State
State

At room temperature, procaine hydrochloride typically exists as a solid in the form of a powder.

Melting point (Celsius)
155.00
Melting point (Kelvin)
428.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
272.78g/mol
Molar mass
272.7790g/mol
Density
1.1700g/cm3
Appearence

Procaine hydrochloride appears as a white crystalline powder. It is odorless and has a slightly bitter taste. The compound is soluble in water, forming a clear solution.

Comment on solubility

Solubility of 2-(diethylamino)ethyl 4-aminobenzoate hydrochloride

The compound 2-(diethylamino)ethyl 4-aminobenzoate; hydrochloride, with the chemical formula C13H21ClN2O2, exhibits notable solubility characteristics that are essential for its applications.

In general, the solubility of this hydrochloride salt can be summarized as follows:

  • Solubility in Water: This compound is typically soluble in water due to the presence of the chloride ion, which can interact favorably with water molecules.
  • Solubility in Organic Solvents: It is moderately soluble in many organic solvents, making it versatile for various reactions and formulations.
  • Temperature Dependence: Like many salts, the solubility may increase with temperature, allowing for better dissolution at elevated temperatures.

It is interesting to note that hydrochlorides often enhance the solubility of base compounds in aqueous solutions, which is particularly beneficial for pharmaceuticals and related industries. As stated, "The formation of a hydrochloride salt can significantly improve the solubility profile of the parent compound," underscoring the importance of such modifications in chemical development.

In conclusion, the solubility properties of 2-(diethylamino)ethyl 4-aminobenzoate hydrochloride establish it as a useful candidate for various applications where effective dissolution is a key factor.

Interesting facts

Interesting Facts About 2-(Diethylamino)ethyl 4-aminobenzoate; Hydrochloride

2-(Diethylamino)ethyl 4-aminobenzoate; hydrochloride is a fascinating compound with a variety of applications, particularly in the field of chemistry and biology. Here are some interesting insights:

  • Pharmaceutical Relevance: This compound is known for its role as a local anesthetic. Its ability to block sodium channels in nerve cells makes it valuable in medical practices where pain relief is essential.
  • Synthetic Pathways: The synthesis of this compound often involves intricate organic reactions. Scientists utilize techniques such as amine protection and ester formation to achieve the desired structure.
  • Biological Functions: Beyond its anesthetic properties, research is ongoing into its potential:
    • Modulation of neurotransmitter release
    • Effects on pain pathways
    • Potential in treating various neurological conditions
  • Analytical Chemistry: Methods such as chromatography are used to analyze and purify this compound. Its unique structure makes it amenable to various spectroscopy techniques that help in understanding its interactions at the molecular level.

In summary, 2-(diethylamino)ethyl 4-aminobenzoate; hydrochloride is not just a chemical compound but a vital component in the medicinal toolbox. Its versatility and functionality make it a point of study for many chemists and scientists dedicated to unveiling the mysteries of chemical interactions and therapeutic applications.

Synonyms
PROCAINE HYDROCHLORIDE
51-05-8
Procaine Hcl
Naucaine
Neocaine
Omnicain
Planocaine
Anestil
Novocain
2-(diethylamino)ethyl 4-aminobenzoate hydrochloride
Atoxicocaine
Neotonocaine
Allocaine
Aminocaine
Anadolor
Anesthesol
Bernocaine
Chlorocaine
Ethocaine
Eugerase
Herocaine
Irocaine
Juvocaine
Kerocaine
Lactocaine
Novocainum
Paracain
Sevicaine
Topokain
Westocaine
Cetain
Isocaine-heisler
Medaject
Rocaine
Syntocain
Rocain
Enpro
Procaine (hydrochloride)
Scurocaine
Benzoic acid, 4-amino-, 2-(diethylamino)ethyl ester, monohydrochloride
Novocaine hydrochloride
Jenacaine
Gero
UNII-95URV01IDQ
EINECS 200-077-2
95URV01IDQ
SP01A
NSC-757280
4-Aminobenzoic acid 2-(diethylamino)ethyl ester hydrochloride
SP-01A
DTXSID1044435
AI3-02404
2-(Diethylamino)ethyl p-aminobenzoate monohydrochloride
p-Aminobenzoyldiethylaminoethanol hydrochloride
MFCD00013000
Procaine (Novocaine) HCl
2-diethylaminoethyl 4-aminobenzoate hydrochloride
2-Diethylaminoethyl p-aminobenzoate hydrochloride
Diethylaminoethanol 4-aminobenzoate hydrochloride
procaine.hcl
CHEBI:8431
p-Aminobenzoic acid 2-diethylaminoethyl ester hydrochloride
DTXCID9024435
EC 200-077-2
Procaine hydrochloride [USP:JAN]
NSC 757280
geriocaine
Benzoic acid, p-amino-, 2-(diethylamino)ethyl ester, monohydrochloride
Gerovital H3
CARDIOPLEGIN COMPONENT PROCAINE HYDROCHLORIDE
Procaine hydrochloride (USP:JAN)
MLS001304095
Benzoic acid, 4-amino-, 2-(diethylamino)ethyl ester, hydrochloride (1:1)
PROCAINE HYDROCHLORIDE (MART.)
PROCAINE HYDROCHLORIDE [MART.]
PROCAINE HYDROCHLORIDE (USP-RS)
PROCAINE HYDROCHLORIDE [USP-RS]
PROCAINE HYDROCHLORIDE (EP IMPURITY)
PROCAINE HYDROCHLORIDE [EP IMPURITY]
PROCAINE HYDROCHLORIDE (EP MONOGRAPH)
PROCAINE HYDROCHLORIDE [EP MONOGRAPH]
PROCAINE HYDROCHLORIDE (USP MONOGRAPH)
PROCAINE HYDROCHLORIDE [USP MONOGRAPH]
CAS-51-05-8
SR-01000076096
NCGC00015864-02
SMR000718771
Procaine hydrochloride [JAN]
Novocaine HCl
Procain HCl
Novocain (TN)
Prestwick_530
Procaine, hydrochloride
Hydrochloride, Procaine
SCHEMBL27720
MLS001336055
MLS001336056
SPECTRUM1500504
HY-B0546AR
CHEMBL1200841
Procaine hydrochloride, >=97%
HY-B0546A
HMS1568I03
HMS1920L06
Pharmakon1600-01500504
PROCAINE HYDROCHLORIDE [MI]
Procaine (hydrochloride) (Standard)
Procaine hydrochloride (JP17/USP)
Tox21_110248
Tox21_302114
Tox21_500966
CCG-39234
NSC757280
s4023
PROCAINE HYDROCHLORIDE [VANDF]
AKOS006029122
Tox21_110248_1
BS-4445
FP32177
KS-5259
LP00966
NC00527
PROCAINE HYDROCHLORIDE [WHO-DD]
NCGC00015864-07
NCGC00094267-01
NCGC00094267-02
NCGC00094267-03
NCGC00094267-04
NCGC00094267-05
NCGC00255993-01
NCGC00261651-01
AC-14461
PROCAINE HYDROCHLORIDE [GREEN BOOK]
PROCAINE HYDROCHLORIDE [ORANGE BOOK]
A1163
EU-0100966
NS00078836
SW196719-3
EN300-02321
PROCAINI HYDROCHLORIDUM [WHO-IP LATIN]
BIM-0050939.0001
C07894
D00740
D78370
P 9879
Procaine.HCl, 1mg/ml in Dmso (as free base)
Q3680934
SR-01000076096-1
SR-01000076096-6
Procaine hydrochloride 100 microg/mL in Acetonitrile
Z104476766
2-(Diethylamino)ethyl 4-aminobenzoate monohydrochloride
Procaine hydrochloride, VETRANAL(TM), analytical standard
Procaine Hydrochloride 1.0 mg/ml in Acetonitrile (as free base)
Procaine hydrochloride, European Pharmacopoeia (EP) Reference Standard
Procaine hydrochloride, United States Pharmacopeia (USP) Reference Standard
Procaine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material
200-077-2