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Procaine

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Identification
Molecular formula
C13H20N2O2
CAS number
59-46-1
IUPAC name
2-(diethylamino)ethyl 4-amino-3-butoxy-benzoate
State
State

At room temperature, Procaine is a solid. It is commonly encountered in its salt form as procaine hydrochloride, which readily dissolves in water to be used in various applications.

Melting point (Celsius)
61.00
Melting point (Kelvin)
334.15
Boiling point (Celsius)
147.00
Boiling point (Kelvin)
420.15
General information
Molecular weight
236.31g/mol
Molar mass
236.3020g/mol
Density
1.1000g/cm3
Appearence

Procaine appears as a white crystalline powder. It is often odorless and can be slightly bitter to taste. In its pure form, it presents as fine, small crystals that may clump together over time in storage.

Comment on solubility

Solubility of 2-(diethylamino)ethyl 4-amino-3-butoxy-benzoate (C13H20N2O2)

The solubility of 2-(diethylamino)ethyl 4-amino-3-butoxy-benzoate is a key factor in its application and effectiveness in various chemical processes. Understanding its solubility can be summarized with the following points:

  • Polar versus Nonpolar: The compound contains both polar and nonpolar functional groups, increasing its chances of being soluble in a variety of solvents. The diethylamino group lends some degree of polarity, aiding solubility in polar solvents.
  • Common Solvents: It is generally soluble in organic solvents such as ethanol and methanol due to the presence of alkyl chains and ether components.
  • Temperature Influence: Like many organic compounds, its solubility can be affected by temperature. Increased temperature typically leads to higher solubility.
  • pH Sensitivity: The solubility may vary with the pH of the solution, especially as the amino groups can interact with acids and bases, altering their protonation state.

In conclusion, while specific solubility data for 2-(diethylamino)ethyl 4-amino-3-butoxy-benzoate can vary, factors such as solvent choice, temperature, and pH must be carefully considered for optimal solubility and utilization in practical applications.

Interesting facts

Interesting Facts about 2-(Diethylamino)ethyl 4-amino-3-butoxy-benzoate

The compound 2-(diethylamino)ethyl 4-amino-3-butoxy-benzoate is a fascinating molecule due to its unique structure and potential applications. Here are some noteworthy points:

  • Pharmaceutical Relevance: This compound is often studied for its role as an intermediate in the synthesis of various pharmaceutical agents. Its structure offers distinct properties that can be manipulated for therapeutic purposes.
  • Structure and Function: The presence of the diethylamino group significantly alters the molecule's solubility and reactivity, making it a versatile building block in medicinal chemistry.
  • Research Applications: Due to its unique functional groups, this compound is a subject of research in fields such as drug design and development. Researchers investigate how modifications to its structure can influence biological activity.
  • Potential Uses: It may be utilized in the formulation of drugs that require a specific release profile or targeted action, due to its ability to interact with certain biological pathways.
  • Synthetic Challenges: The synthesis of this compound can involve complex reactions and purification steps, often requiring skilled techniques in organic chemistry.

In summary, 2-(diethylamino)ethyl 4-amino-3-butoxy-benzoate serves as a compelling example of how small changes in chemical structure can lead to significant variations in functionality. Its exploration contributes to the ongoing advancements in the pharmaceutical field, where the quest for more effective drugs continues.

Synonyms
Oxybuprocaine
Benoxinate
Oxybucaine
99-43-4
2-(Diethylamino)ethyl 4-amino-3-butoxybenzoate
Oxyriprocaine
Oxibuprokain
Conjucain
Benoxil
Oxibuprocainum
Prescaina
Oxibuprocaina
Dorsacain
Novesinol
Oxybuprocainum
Butoxyaminobenzoyldiethylaminoethanol
Oxybuprocaine [INN:BAN]
Oxbarukain
Monofree oxybuprocaine
Oxybuprocainum [INN-Latin]
Oxibuprocaina [INN-Spanish]
4-Amino-3-butoxy-2-(diethylamino)ethyl ester benzoic acid
S 749
CHEBI:309594
4-Amino-3-n-butoxy-benzoesaeure-diaethylaminoaethylester
Oxybuprocaine (INN)
BENZOIC ACID, 4-AMINO-3-BUTOXY-, 2-(DIETHYLAMINO)ETHYL ESTER
AXQ0JYM303
Monofree oxybuprocaine (TN)
4-Amino-3-butoxy-benzoic acid 2-diethylamino-ethyl ester
Minims Oxybuprocaine
BRN 2288926
BENOXINATE [MI]
BENOXINATE [VANDF]
OXYBUPROCAINE [INN]
4-Amino-3-n-butoxy-benzoesaeure-diaethylaminoaethylester [German]
4-Amino-3-butoxybenzoic acid 2-diethylaminoethyl ester
OXYBUPROCAINE [WHO-DD]
butoxyprocaine
DTXSID7048530
Novescine
Oxybuprocainum (INN-Latin)
2-(Diethylamino)ethyl 4-amino-3-butoxy-benzoate
Oxibuprocaina (INN-Spanish)
Benoxinate;Conjucain; Dorsacain; Novesinol; Oxybucaine
SMR000857098
diethylaminoethyl-4-amino-3-butoxybenzoate
BENZOIC ACID, 4-AMINO-3-BUTOXY-, 2-(DIETHYLAMINO)ETHYL ESTER, HYDROCHLORIDE
2-Diethylaminoethyl 4-amino-3-butoxybenzoate
NCGC00016667-01
CAS-5987-82-6
UNII-AXQ0JYM303
4-Amino-3-butoxybenzoic acid 2-(diethylamino)ethyl ester
BNX
MFCD00242863
3-Butoxy-4-aminobenzoic acid 2-(diethylamino)ethyl ester
2-(4-amino-3-butoxybenzoyl)oxyethyl-diethylazanium chloride
Prestwick0_000057
Prestwick1_000057
Prestwick2_000057
Prestwick3_000057
Epitope ID:122669
CHEMBL1200
2-(diethylamino)ethyl 4-amino-3-n-butoxybenzoate
SCHEMBL25087
BSPBio_000213
MLS001332643
MLS001332644
SPBio_002134
3-Butoxy-4-aminobenzoic acid 2-diethylaminoethyl ester
BPBio1_000235
GTPL7123
DTXCID4027997
HY-B1288A
D04AB03
S01HA02
HMS2235J23
HMS3369H13
HMS3604F05
ALBB-025704
BBL003343
BDBM50225499
STK520615
AKOS005457803
Benzoic acid, 4-amino-3-butoxy-, 2-(diethylamino)ethyl ester (7CI,8CI,9CI)
DB00892
NCGC00016667-02
NCGC00016667-05
BS-18026
DA-76519
4675B
CS-0013333
NS00002761
2-(Diethylamino)ethyl4-amino-3-butoxybenzoate
D08319
D83117
EN300-17989125
Q1530958
BRD-K04185004-003-03-6
BRD-K04185004-003-11-9
BRD-K04185004-003-12-7
BRD-K04185004-003-13-5
2-(4-amino-3-butoxy-benzoyl)oxyethyl-diethyl-ammonium chloride