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Procaine

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Identification
Molecular formula
C13H20N2O2
CAS number
59-46-1
IUPAC name
2-(diethylamino)ethyl 3-amino-4-propoxy-benzoate
State
State

At room temperature, procaine is typically found as a solid crystalline compound when not dissolved or formulated with other compounds. It is frequently used in aqueous solutions in medical applications as a local anesthetic.

Melting point (Celsius)
61.00
Melting point (Kelvin)
334.15
Boiling point (Celsius)
365.95
Boiling point (Kelvin)
639.10
General information
Molecular weight
236.31g/mol
Molar mass
236.3090g/mol
Density
1.1000g/cm3
Appearence

Procaine is a white, crystalline, odorless powder. It is commonly used in medical applications, often as a hydrochloride salt form which also appears as a white crystalline powder. It is sparingly soluble in water.

Comment on solubility

Solubility of 2-(diethylamino)ethyl 3-amino-4-propoxy-benzoate (C13H20N2O2)

The solubility of 2-(diethylamino)ethyl 3-amino-4-propoxy-benzoate in various solvents is an important characteristic that influences its applications. Understanding its solubility profile can aid in determining the suitable conditions for its use. Here are some key points regarding its solubility:

  • Solvent Polarity: This compound is likely to be moderately soluble in polar solvents such as water due to the presence of amine functional groups that can engage in hydrogen bonding.
  • Nonpolar Solvents: It may find better solubility in nonpolar solvents like hexane or octane, which would accommodate its hydrophobic propoxy group.
  • Concentration Effects: The solubility can be influenced by concentration, temperature, and the presence of other solutes in the solution.

As a quaternary ammonium compound, its ionization state can also alter solubility; thus, studying it under different pH conditions is important. In summary, the solubility of 2-(diethylamino)ethyl 3-amino-4-propoxy-benzoate is determined by a balance of its polar and nonpolar characteristics, making it versatile for various applications in chemistry and pharmaceuticals.

Interesting facts

Interesting Facts about 2-(Diethylamino)ethyl 3-amino-4-propoxy-benzoate

2-(Diethylamino)ethyl 3-amino-4-propoxy-benzoate is a compound that exhibits a unique combination of properties in the realm of organic chemistry. Here are some fascinating points about this compound:

  • Applications in Pharmaceuticals: This compound is often studied for its potential uses in the pharmaceutical industry, particularly as a drug candidate due to its structural modifications that can enhance biological activity.
  • Structure-Activity Relationship: The presence of both the diethylamino and propoxy functional groups provides insight into how altering structure can influence reactivity and bioavailability. This relationship is crucial in the design of more effective therapeutic agents.
  • Research Interests: Scientists are intrigued by the dual amine and ether functionalities which may yield interesting reactions, making this compound a potential subject in synthetic organic chemistry.
  • Studying Reactivity: The benzoate moiety in this compound may contribute to the compound’s stability and can be subjected to various organic reactions, such as esterifications and coupling reactions, which are vital in synthetic pathways.
  • Electronics and Material Science: Beyond pharmaceuticals, compounds with similar structures have been explored in the field of material science for their electronic properties, possibly leading to innovations in molecular electronics.

As a chemistry student or scientist, appreciating the multifaceted nature of such compounds can lead to breakthroughs in drug development and other innovative applications. Remember, the journey of discovery often begins with the exploration of seemingly complex molecular structures!

Synonyms
proparacaine
Proxymetacaine
499-67-2
2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate
Proximetacainum
Ophthaine
Proximetacaina
Prossimetacaina
Prossimetacaina [DCIT]
Proxymetacainum
Paracaine
Alcaine
Proxymetacainum [INN-Latin]
Proximetacaina [INN-Spanish]
Kainair
Ophthetic
3-Amino-4-propoxybenzoic acid 2-(diethylamino)ethyl ester
UNII-B4OB0JHI1X
B4OB0JHI1X
beta-(Diethylamino)ethyl 4-n-propoxybenzoate
EINECS 207-884-9
BENZOIC ACID, 3-AMINO-4-PROPOXY-, 2-(DIETHYLAMINO)ETHYL ESTER
BRN 2745891
CHEBI:8485
Proxymetacaine (INN)
DTXSID30198146
PROXYMETACAINE [INN]
Proxymetacainum (INN-Latin)
Proximetacaina (INN-Spanish)
Proxymetacaine [INN:BAN]
NCGC00016991-03
proxymethacaine
Prestwick0_000959
Prestwick1_000959
Prestwick2_000959
Prestwick3_000959
PROPARACAINE [MI]
CHEMBL1196
PROPARACAINE [VANDF]
SCHEMBL23334
BSPBio_000958
MLS006011856
SPBio_003107
BPBio1_001054
GTPL7283
PROXYMETACAINE [WHO-DD]
DTXCID60120637
S01HA04
HMS3604H05
ALBB-025705
BCP22476
BBL003355
BDBM50225500
STK520616
AKOS005457804
DB00807
CAS-1452000
MRF-0000607
NCGC00016991-01
NCGC00016991-02
NCGC00016991-06
NCGC00016991-13
AC-13440
SMR000857219
SBI-0206900.P001
AB00444123
NS00001066
.beta.-(Diethylamino)ethyl 4-n-propoxybenzoate
C07383
D08448
AB00444123_07
AB00444123_08
2-(Diethylamino)ethyl 3-amino-4-propoxy-benzoate
EN300-22731623
Q600867
BRD-K79116891-003-03-7
BRD-K79116891-003-14-4
BRD-K79116891-003-15-1
3-amino-4-propoxy-,2-(diethylamino)ethyl ester Benzoic acid
3-AMINO-4-PROPOXY-BENZOIC ACID 2-DIETHYLAMINO-ETHYL ESTER, HYDROCHLORIDE
207-884-9