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Cocaine

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Identification
Molecular formula
C17H21NO4
CAS number
50-36-2
IUPAC name
2-(diethylamino)ethyl 1-phenylcyclopentanecarboxylate
State
State

At room temperature, cocaine is typically a solid in the form of a crystalline powder.

Melting point (Celsius)
98.00
Melting point (Kelvin)
371.15
Boiling point (Celsius)
187.00
Boiling point (Kelvin)
460.15
General information
Molecular weight
303.35g/mol
Molar mass
303.3530g/mol
Density
1.3030g/cm3
Appearence

Cocaine is a white crystalline tropane alkaloid that has a bitter, numbing taste. It is usually seen as a fine white powder, although forms like crack cocaine appear as small lumps or rocks.

Comment on solubility

Solubility of 2-(diethylamino)ethyl 1-phenylcyclopentanecarboxylate

The solubility of 2-(diethylamino)ethyl 1-phenylcyclopentanecarboxylate can be understood by considering several critical factors:

  • Polarity: This compound exhibits a moderate polarity due to the presence of the diethylamino group and the ester functional group.
  • Solvent interactions: Its solubility is likely to be favorable in polar organic solvents such as ethanol and methanol, yet less so in nonpolar solvents like hexane.
  • Temperature Dependence: As with many organic compounds, increased temperature may enhance solubility, leading to a greater dissolution of the compound in a solvent.

Moreover, empirical studies indicate that the presence of the bulky phenyl group can influence solubility. The bulky aromatic structure may hinder the compound’s ability to interact closely with solvent molecules, possibly resulting in lower solubility in highly polar solvents. Nonetheless, it is essential to note that solubility can vary significantly under different conditions.

In summary, the solubility of 2-(diethylamino)ethyl 1-phenylcyclopentanecarboxylate is dictated by:

  1. Polarity and functional groups
  2. Choice of solvent
  3. Temperature and pressure conditions
  4. Molecular architecture with steric factors

Understanding these attributes is crucial for predicting and optimizing the solubility of this compound in various applications.

Interesting facts

Interesting Facts about 2-(diethylamino)ethyl 1-phenylcyclopentanecarboxylate

2-(diethylamino)ethyl 1-phenylcyclopentanecarboxylate is an intriguing compound that showcases the fascinating intersection of organic chemistry and medicinal applications. Here are some compelling aspects of this molecule:

  • Compound Class: This compound belongs to the family of carboxylates, which are well-known for their extensive use in pharmaceuticals, particularly as intermediates in drug synthesis.
  • Structure and Configuration: The molecule features a cyclopentane ring, which contributes to its conformational flexibility, allowing for various interactions with biological targets.
  • Potential Applications: With the presence of a diethylamino group, this compound is of interest in the development of anesthetic agents and could potentially be used in pain management therapies.
  • Synthesis Interest: Chemists find the synthesis of such compounds stimulating, as it often involves multi-step reactions that challenge synthetic methodologies and strategic planning.
  • Interactions with Receptors: The unique structural features of this compound may enable it to interact with certain receptors in the nervous system, which is a topic of ongoing research.

Quoting the renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." The study of compounds like 2-(diethylamino)ethyl 1-phenylcyclopentanecarboxylate exemplifies this, enriching our understanding of organic compounds and their potential in medicinal chemistry.

Overall, this compound presents a blend of complexity and utility, making it a fascinating subject for both chemists and those interested in the future of pharmaceuticals.

Synonyms
Caramiphen
77-22-5
Parpanil
Caramiphene
Pentaphen (pharmaceutical)
2-(diethylamino)ethyl 1-phenylcyclopentane-1-carboxylate
1-Phenylcyclopentanecarboxylic acid 2-(diethylamino)ethyl ester
97J7NP0XJY
CYCLOPENTANECARBOXYLIC ACID, 1-PHENYL-, 2-(DIETHYLAMINO)ETHYL ESTER
CHEMBL61946
Cyclopentanecarboxylicacid, 1-phenyl-, 2-(diethylamino)ethyl ester
2-(Diethylamino)ethyl 1-phenylcyclopentanecarboxylate
2-Diethylaminoethyl 1-phenylcyclopentane-1-carboxylate
Caramifenio
Caramiphenum
Caramiphen [INN:BAN]
MLS000532799
Caramiphene [INN-French]
Caramiphenum [INN-Latin]
Caramifenio [INN-Spanish]
SMR000140237
EINECS 201-013-6
UNII-97J7NP0XJY
BRN 2144901
diethylaminoethyl 1-phenylcyclopentane-1-carboxylate
Caramifeno
2-Diethylaminoethyl 1-phenylcyclopentancarboxylat
2-(diethylamino)ethyl 1-phenylcyclopentanecarboxylate hydrochloride
Caramiphen (free base)
CARAMIPHEN [MI]
Pentoxyverine impurity B
CARAMIPHEN [INN]
CARAMIPHEN [VANDF]
CARAMIPHEN [WHO-DD]
cid_67173
SCHEMBL181285
DTXSID0022729
BDBM73402
CHEBI:135204
PDSP1_000069
PDSP2_000069
STK179630
AKOS001662910
DB11504
NCGC00167426-02
NS00002057
SBI-0653890.0001
AB00088177-01
AB00088177-10
EN300-23519761
Q5037673
BRD-K59895502-001-01-9
2-(Diethylamino)ethyl 1-phenylcyclopentanecarboxylate #
2-Dimethylaminoethyl 1-phenylcyclopentane-1-carboxylate
Z252849348
1-(2-DIETHYLAMINOETHOXYCARBONYL)-1-PHENYLCYCLOPENTANE
1-Phenyl-cyclopentanecarboxylic acid 2-diethylamino-ethyl ester
1-phenylcyclopentanecarboxylic acid 2-(diethylamino)ethyl ester;hydrochloride
1-phenyl-1-cyclopentanecarboxylic acid 2-(diethylamino)ethyl ester;hydrochloride