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Methylene Blue

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Identification
Molecular formula
C16H18N3SCl
CAS number
61-73-4
IUPAC name
2-(diethylamino)-1-phenothiazin-10-yl-propan-1-one
State
State

At room temperature, methylene blue is typically found in its solid form as a dark green powder. When dissolved, particularly in water, it transitions to a blue solution.

Melting point (Celsius)
100.00
Melting point (Kelvin)
373.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
319.85g/mol
Molar mass
319.8520g/mol
Density
1.3000g/cm3
Appearence

Methylene blue is a solid compound that appears as a dark green powder at room temperature. In solution, particularly in aqueous solutions, it exhibits a blue coloration, hence its name. This vibrant blue color is one of the most distinctive characteristics and is used in applications ranging from biological staining to medical diagnostics and treatments.

Comment on solubility

Solubility of 2-(diethylamino)-1-phenothiazin-10-yl-propan-1-one

The solubility of 2-(diethylamino)-1-phenothiazin-10-yl-propan-1-one, with the chemical formula C16H18N3SCl, can present some intriguing characteristics worth exploring. As a compound containing both aromatic (phenothiazine) and aliphatic (diethylamino) components, its solubility behavior may vary greatly in different solvents.

Key Points about Solubility:

  • Polar vs. Nonpolar: Due to the presence of the polar diethylamino group, the compound is expected to exhibit higher solubility in polar solvents such as water and methanol. However, the hydrophobic phenothiazine component may reduce this solubility.
  • Common Solvents: Likely soluble in organic solvents like ethanol, dimethyl sulfoxide (DMSO), and acetone, while being less soluble in nonpolar solvents.
  • Temperature Influence: Increasing temperature can often enhance solubility for most organic compounds, allowing for better dissolution in aqueous solutions.

In practical applications, understanding the solubility of this compound is crucial for its formulation in pharmaceuticals and other chemical processes. It is important to conduct empirical tests as solubility can also be influenced by factors such as pH, ionic strength, and interactions with other solutes. Hence, empirical data is often required to fully assess its behavior in various environments.

Interesting facts

Interesting Facts about 2-(Diethylamino)-1-phenothiazin-10-yl-propan-1-one

2-(Diethylamino)-1-phenothiazin-10-yl-propan-1-one, often referred to in its abbreviated form, is a chemical compound that has garnered interest due to its unique structural features and potential applications. Here are some intriguing aspects of this compound:

  • Complex Structure: The compound features a phenothiazine moiety, which is a tricyclic structure that contains both sulfur and nitrogen atoms. This arrangement is noteworthy for its role in psychopharmacology.
  • Pharmacological Properties: Due to the presence of the phenothiazine scaffold, compounds like this one have been studied for their therapeutic effects, particularly as antipsychotics and antihistamines. They can influence neurotransmitter pathways, making them vital in treating various mental health disorders.
  • Diethylamino Group: The diethylamino group is known for enhancing lipid solubility, which can influence the compound's bioavailability and pharmacokinetics. This plays a critical role in how effectively the drug acts within the body.
  • Unique Mechanism: Compounds based on phenothiazines often interact with dopamine receptors, presenting a potential mechanism for their action as neuroleptics.
  • Research Importance: The study of such compounds is essential not only for understanding their therapeutic applications but also for exploring their toxicological profiles. It’s fascinating to see how slight modifications in chemical structure can significantly alter biological activity.

Overall, 2-(diethylamino)-1-phenothiazin-10-yl-propan-1-one exemplifies the intricate relationship between chemistry and pharmacology, and its ongoing study can lead to significant advancements in mental health treatment strategies.

Synonyms
Methyldifazine
AS-1397
10-(2-(Diethylamino)propionyl)phenothiazine
NIOSH/SO4600000
SO46000000
Phenothiazine, 10-(2-(diethylamino)propionyl)-
10-(alpha-Diethylaminopropionyl)-phenothiazine hydrochloride
Lopac0_000351
CHEMBL376514
SCHEMBL1320997
BDBM13551
2-(diethylamino)-1-(10H-phenothiazin-10-yl)propan-1-one
CCG-204446
10-(a-diethyl-aminopropionyl)-phenothiazine
10-[2-(diethylamino)-1-oxopropyl]-10H-phenothiazine