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Clonidine

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Identification
Molecular formula
C6H7Cl
CAS number
61-25-6
IUPAC name
(2-chlorophenyl)-[2-[2-(diethylaminomethyl)imidazol-1-yl]-5-nitro-phenyl]methanone
State
State

At room temperature, clonidine is in a solid state.

Melting point (Celsius)
184.50
Melting point (Kelvin)
457.65
Boiling point (Celsius)
517.80
Boiling point (Kelvin)
790.95
General information
Molecular weight
230.68g/mol
Molar mass
230.6770g/mol
Density
1.5510g/cm3
Appearence

Clonidine appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of (2-chlorophenyl)-[2-[2-(diethylaminomethyl)imidazol-1-yl]-5-nitro-phenyl]methanone

The solubility of the compound (2-chlorophenyl)-[2-[2-(diethylaminomethyl)imidazol-1-yl]-5-nitro-phenyl]methanone with the formula C6H7Cl can be influenced by several factors.

Factors Affecting Solubility

  • Polarity: The presence of chlorine and nitro groups in the molecule adds to its polarity, potentially increasing its solubility in polar solvents.
  • Hydrophobic and Hydrophilic Balance: The distribution of hydrophobic and hydrophilic regions in the compound impacts how readily it dissolves in various solvents.
  • Temperature: Increasing the temperature generally enhances solubility for many organic compounds, though this can vary based on specific interactions in the solution.
  • pH of the solvent: Adjusting the pH can either protonate or deprotonate certain groups in the compound, affecting its solubility.

In general, compounds of this nature tend to exhibit moderate solubility in organic solvents such as ethanol or acetone but might have limited solubility in water due to the presence of larger nonpolar regions competing with the polar functionalities.

It is also important to note that solubility values can vary significantly between sources. Therefore, experimental determination is crucial for accurate assessments.

Interesting facts

Interesting Facts about (2-chlorophenyl)-[2-[2-(diethylaminomethyl)imidazol-1-yl]-5-nitro-phenyl]methanone

(2-chlorophenyl)-[2-[2-(diethylaminomethyl)imidazol-1-yl]-5-nitro-phenyl]methanone, commonly referred to as a complex organic compound, showcases intriguing properties and applications that capture the curiosity of both chemists and enthusiasts alike. Here are some notable aspects:

  • Structural Diversity: This compound features a unique combination of structural elements, including a chlorophenyl group, an imidazole moiety, and nitrophenyl component. This structural complexity contributes to its potential biological activity.
  • Potential Applications: Compounds of this nature may exhibit pharmacological properties. Imidazole derivatives are often investigated for their role in medicinal chemistry, including anti-inflammatory and antimicrobial activity.
  • Mechanism of Action: The presence of the diethylaminomethyl group is significant as it could influence the compound's interaction with biological targets, potentially enhancing its bioactivity.
  • Research Relevance: Due to its unique structure, this compound may serve as a lead compound in drug development, prompting researchers to explore its synthetic pathways and modifications for enhanced therapeutic effects.

Overall, the exploration of (2-chlorophenyl)-[2-[2-(diethylaminomethyl)imidazol-1-yl]-5-nitro-phenyl]methanone opens doors to numerous research opportunities and contributes to the ongoing advancement in the field of chemistry. As noted in studies, "The integration of diverse functional groups in organic compounds is crucial for developing novel therapeutic agents."

Synonyms
Nizofenone
54533-85-6
Nizofenone [INN]
Nizofenona
Nizofenonum
Nizofenonum [INN-Latin]
Nizofenona [INN-Spanish]
(2-Chlorophenyl)(2-(2-((diethylamino)methyl)-1H-imidazol-1-yl)-5-nitrophenyl)methanone
UNII-7A2NOC3R88
Nizofenone (INN)
7A2NOC3R88
NIZOFENONE [MI]
NIZOFENONE [JAN]
Y 9179
NIZOFENONE [MART.]
NIZOFENONE [WHO-DD]
2'-Chlor-2-(2-(diethylaminomethyl)-1-imidazolyl)-5-nitrobenzophenon
DTXSID401014745
2'-Chloro-2-(2-((diethylamino)methyl)imidazol-1-yl)-5-nitrobenzophenone
(2-chlorophenyl)-[2-[2-(diethylaminomethyl)imidazol-1-yl]-5-nitrophenyl]methanone
Nizofenonum (INN-Latin)
Nizofenona (INN-Spanish)
NIZOFENONE (MART.)
NCGC00183104-01
((1-(2-(2-chlorobenzoyl)-4-nitrophenyl)-1H-imidazol-2-yl)methyl)diethylamine
({1-[2-(2-chlorobenzoyl)-4-nitrophenyl]-1H-imidazol-2-yl}methyl)diethylamine
Y-1979
Oprea1_229738
SCHEMBL855561
CHEMBL2106822
DTXCID2028563
N06BX10
CHEBI:135668
1-(2-(2-chlorobenzoyl)-4-nitrophenyl)-2-(diethylaminomethyl)imidazole
AKOS015909167
AKOS040749029
AC-1324
DB13546
HY-119513
CS-0068612
D08280
BRD-K84011460-051-01-7
Q15409362
(2-Chlorophenyl)(2-{2-[(diethylamino)methyl]-1H-imidazol-1-yl}-5- nitrophenyl)methanone